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Stoqly stoqly.net Company report Β· October 27, 2026

Rhythm Pharmaceuticals, Inc.

RYTM NasdaqΒ· Pharmaceutical Preparations

Last close Β· Oct 26, 2026

$89.47

KIRA Β· Stoqly’s AI analyst, in plain words

  • Rhythm Pharmaceuticals, Inc. had $190M of revenue in fiscal 2025, up 45.8% on the year before.
  • Its operating margin was βˆ’101.2%, up 102.8Β pts: of every 100 in sales, about βˆ’101 is left after running the business.
  • Rhythm Pharmaceuticals, Inc. lost $197M in fiscal 2025.
  • Free cash flow was βˆ’$117M in fiscal 2025, βˆ’61.5% of revenue.
  • Rhythm Pharmaceuticals, Inc. has $281M more cash than debt.

Market cap

$6.1B

P/E

β€”

Revenue

$190M

Net income

βˆ’$197M

Free cash flow

βˆ’$117M

Operating margin

βˆ’101.2%

Rhythm Pharmaceuticals, Inc. in 30 seconds Β· fiscal 2025

Good

Are sales growing?

+45.8%

Yes. Sales grew 45.8% last year.

Weak

Does it make a profit?

βˆ’103.6%

No. It lost money last year.

Weak

Does profit turn into cash?

βˆ’61.5%

No. It spent more cash than it brought in.

So-so

How healthy are the accounts?

6 / 9

Mixed. It passes 6 of 9 health tests.

For information

How is the share priced?

β€”

No P/E: it made no profit over the last four quarters.

What Rhythm Pharmaceuticals, Inc. does

No business description yet.

Fiscal year ends
December 31, 2025
Latest annual report
10-K Β· Feb 26, 2026
Legal name
RHYTHM PHARMACEUTICALS, INC.
CIK
0001649904
stoqly.net Β· RYTM Β· Generated October 27, 2026 Not investment advice Β· Page 1 of 3
Stoqly stoqly.net Company report Β· October 27, 2026

Rhythm Pharmaceuticals, Inc. Β· RYTM

Results and finances

The last 5 fiscal years. Amounts in USD.

Fiscal yearFY21FY22FY23FY24FY25
Sales and profit
Revenue $3.2M $23.6M $77.4M $130M $190M
Revenue growth β€” 649.5% 227.6% 68.1% 45.8%
Gross margin 81.0% 91.0% 88.0% 89.7% 89.7%
Operating margin βˆ’5,391.9% βˆ’757.9% βˆ’238.1% βˆ’204.0% βˆ’101.2%
Net income βˆ’$69.6M βˆ’$181M βˆ’$185M βˆ’$261M βˆ’$197M
Net margin βˆ’2,207.1% βˆ’766.2% βˆ’238.5% βˆ’200.3% βˆ’103.6%
Diluted EPS βˆ’$1.40 βˆ’$3.47 βˆ’$3.20 βˆ’$4.34 βˆ’$3.11
Cash
Cash from operations βˆ’$146M βˆ’$173M βˆ’$136M βˆ’$114M βˆ’$116M
Capital expenditure $0.4M $0.3M $0.0M $0.0M $1.0M
Free cash flow βˆ’$146M βˆ’$174M βˆ’$136M βˆ’$114M βˆ’$117M
FCF margin βˆ’4,642.9% βˆ’734.9% βˆ’175.9% βˆ’87.5% βˆ’61.5%
Share count change 12.4% 5.1% 10.7% 5.8% 6.5%
Debt and strength
Cash and short-term investments $295M $333M $276M $321M $389M
Debt incl. finance leases β€” β€” $106M $110M $108M
Shareholders' equity $284M $264M $170M $21.7M $139M
Current ratio 7.1x 8.9x 5.6x 3.2x 4.4x
Interest coverage β€” βˆ’34.4x βˆ’13.3x βˆ’12.9x βˆ’9.3x
Returns and quality
Return on capital β€” β€” βˆ’260,075.1% β€” β€”
Return on equity βˆ’30.9% βˆ’66.1% βˆ’85.1% βˆ’272.2% βˆ’244.5%
Return on tangible equity βˆ’24.9% βˆ’70.6% βˆ’113.5% βˆ’1,700.9% βˆ’151.0%
Piotroski F-score 2 4 2 4 6
Altman Z'' 3.1 βˆ’1.5 βˆ’6.4 βˆ’9.7 βˆ’6.2

Insiders bought, 12 months

$0.0M

0 insiders

Insiders sold, 12 months

$40.1M

9 insiders

Of sales under plans

98%

$39.2M

How to read these numbers

Revenue:
Total sales reported in the income statement.
Operating margin:
Operating income as a share of revenue.
Net income:
Profit after all expenses, interest and tax.
Free cash flow:
Cash from operations minus capital spending.
Net debt / EBITDA:
Years of EBITDA needed to pay off net debt. Below zero means more cash than debt.
Return on capital:
After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.
stoqly.net Β· RYTM Β· Generated October 27, 2026 Not investment advice Β· Page 2 of 3
Stoqly stoqly.net Company report Β· October 27, 2026

Rhythm Pharmaceuticals, Inc. Β· RYTM

Charts and comparison

Ten years at a glance, and how it stacks up against similar companies.

Revenue

Net income

Margins, % of revenue

Gross Operating Net

Cash vs debt (incl. leases)

Cash Debt

Free cash flow

Dividends and buybacks

Dividends Buybacks

KIRA

At $89.47 a share, the company is worth $6.1B.

Source: SEC EDGAR XBRL filings (CIK 0001649904). Data updated October 24, 2026. For information only β€” not investment advice. Check the original filings before relying on any figure.