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Stoqly stoqly.net Company report Β· October 27, 2026

Spruce Biosciences, Inc.

SPRB NasdaqΒ· Pharmaceutical Preparations

Last close Β· Oct 26, 2026

$43.99

KIRA Β· Stoqly’s AI analyst, in plain words

  • Spruce Biosciences, Inc. had $0.0M of revenue in fiscal 2025, down 100.0% on the year before.
  • Spruce Biosciences, Inc. lost $39.0M in fiscal 2025.
  • Spruce Biosciences, Inc. has $48.9M more cash than debt.

Market cap

$107M

P/E

β€”

Revenue

$0.0M

Net income

βˆ’$39.0M

Free cash flow

β€”

Operating margin

β€”

Spruce Biosciences, Inc. in 30 seconds Β· fiscal 2025

Weak

Are sales growing?

βˆ’100.0%

No. Sales fell 100.0% last year.

Weak

Does it make a profit?

βˆ’$39.0M

No. It lost money last year.

So-so

How healthy are the accounts?

4 / 8

Mixed. It passes 4 of 8 health tests.

For information

How is the share priced?

β€”

No P/E: it made no profit over the last four quarters.

What Spruce Biosciences, Inc. does

No business description yet.

Fiscal year ends
December 31, 2025
Latest annual report
10-K Β· Mar 9, 2026
Legal name
SPRUCE BIOSCIENCES, INC.
CIK
0001683553
stoqly.net Β· SPRB Β· Generated October 27, 2026 Not investment advice Β· Page 1 of 3
Stoqly stoqly.net Company report Β· October 27, 2026

Spruce Biosciences, Inc. Β· SPRB

Results and finances

The last 5 fiscal years. Amounts in USD.

Fiscal yearFY21FY22FY23FY24FY25
Sales and profit
Revenue β€” $0.0M $10.1M $4.9M $0.0M
Revenue growth β€” β€” β€” βˆ’51.3% βˆ’100.0%
Operating margin β€” β€” βˆ’515.3% βˆ’1,143.4% β€”
Net income βˆ’$42.3M βˆ’$46.2M βˆ’$47.9M βˆ’$53.0M βˆ’$39.0M
Net margin β€” β€” βˆ’475.0% βˆ’1,079.9% β€”
Diluted EPS βˆ’$1.81 βˆ’$1.96 βˆ’$1.24 βˆ’$96.40 βˆ’$50.83
Cash
Cash from operations βˆ’$35.9M βˆ’$41.7M βˆ’$33.3M βˆ’$56.0M βˆ’$33.3M
Capital expenditure $0.1M $0.0M $0.0M $0.0M β€”
Free cash flow βˆ’$36.0M βˆ’$41.7M βˆ’$33.3M βˆ’$56.0M β€”
FCF margin β€” β€” βˆ’329.9% βˆ’1,139.6% β€”
Share count change 289.9% 0.7% 63.7% βˆ’98.6% 39.4%
Debt and strength
Cash and short-term investments $89.0M $79.1M $96.3M $38.8M $48.9M
Debt incl. finance leases $4.9M $5.6M $3.7M $1.8M $0.0M
Shareholders' equity $111M $68.5M $76.5M $28.8M $42.5M
Current ratio 10.4x 6.7x 4.2x 2.9x 5.2x
Interest coverage βˆ’121.9x βˆ’112.6x βˆ’107.6x βˆ’182.9x βˆ’405.7x
Returns and quality
Return on capital βˆ’121.8% β€” β€” β€” β€”
Return on equity βˆ’32.4% βˆ’51.4% βˆ’66.1% βˆ’100.7% βˆ’109.2%
Return on tangible equity βˆ’38.0% βˆ’67.4% βˆ’62.6% βˆ’184.0% βˆ’91.7%
Piotroski F-score 1 1 4 2 4
Altman Z'' 7.1 0.2 βˆ’1.7 βˆ’20.3 βˆ’13.0

Insiders bought, 12 months

$0.0M

0 insiders

Insiders sold, 12 months

$0.0M

0 insiders

Of sales under plans

β€”

$0.0M

How to read these numbers

Revenue:
Total sales reported in the income statement.
Operating margin:
Operating income as a share of revenue.
Net income:
Profit after all expenses, interest and tax.
Free cash flow:
Cash from operations minus capital spending.
Net debt / EBITDA:
Years of EBITDA needed to pay off net debt. Below zero means more cash than debt.
Return on capital:
After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.
stoqly.net Β· SPRB Β· Generated October 27, 2026 Not investment advice Β· Page 2 of 3
Stoqly stoqly.net Company report Β· October 27, 2026

Spruce Biosciences, Inc. Β· SPRB

Charts and comparison

Ten years at a glance, and how it stacks up against similar companies.

Revenue

Net income

Margins, % of revenue

Gross Operating Net

Cash vs debt (incl. leases)

Cash Debt

Free cash flow

Dividends and buybacks

Dividends Buybacks

KIRA

At $43.99 a share, the company is worth $107M.

Source: SEC EDGAR XBRL filings (CIK 0001683553). Data updated October 24, 2026. For information only β€” not investment advice. Check the original filings before relying on any figure.