1.Sales and profit
See section β- Summit Therapeutics Inc. lost $1.1B in fiscal 2025.
SMMT Nasdaq Pharmaceutical Preparations Financials FY2018βFY2025
Last close Β· Oct 26, 2026
$14.50
β$4.78 (β24.79%) past year
Hi! I read Summit Therapeutics Inc.βs latest annual report (fiscal 2025). Here is what stands out:
Good So-so Weak
Does it make a profit?
β$1.1B
No. It lost money last year.
How is the share priced?
β
No P/E: it made no profit over the last four quarters.
Rules of thumb on reported numbers. A starting point, not a recommendation.
Is it selling more, and how much does it keep?
Revenue
Revenue
Margins, % of revenue
In plain words: Revenue is all the money customers paid. The margins show how many cents of each dollar of sales are left over at each step: after making the product (gross), after running the business (operating) and after everything, tax included (net).
Loss periods are shown in red.
KIRA summarises the numbers
Summit Therapeutics Inc. lost $1.1B in fiscal 2025.
Net income
Net income
Diluted EPS
Diluted EPS
In plain words: Net income is the profit left after every cost and tax. Earnings per share (EPS) splits that profit across every share, so it shows what one share earned.
How much cash comes in, and where does it go?
Cash from operations minus capital spending.
KIRA summarises the numbers
Free cash flow was β$324M in fiscal 2025, β of revenue.
Free cash flow
Free cash flow
Cash from operations vs capital spending
Cash from operations vs capital spending
In plain words: Profit on paper is not the same as cash in the bank. Free cash flow is the cash left after paying to run and maintain the business: the money it can hand back to shareholders, save or invest.
Dividends and buybacks
Diluted shares outstanding (annual)
In plain words: Companies hand cash back in two ways: dividends (cash paid to shareholders) and buybacks (buying back their own shares, so each remaining share owns a bigger slice).
Open-market purchases and sales by officers, directors and 10% owners, from Form 4 filings. βPlanβ marks trades under a pre-arranged Rule 10b5-1 plan.
KIRA summarises the numbers
In the last 12 months, insiders bought $104M of shares on the open market and sold none.
Bought, 12 months
$104M
3 insiders
Sold, 12 months
$0.0M
0 insiders
Of sales under plans
β
$0.0M
| Date | Insider | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| Jun 12, 2026 | Mahkam ZanganehCo-Chief Executive Officer, Director, 10% owner | Bought | 3,810,000 | $13.12 | $50.0M | Form 4 |
| Jun 12, 2026 | Robert W DugganCo-Chief Executive Officer, Director, 10% owner | Bought | 3,810,000 | $13.12 | $50.0M | Form 4 |
| Jun 4, 2026 | Mahkam ZanganehCo-Chief Executive Officer, Director, 10% owner | Bought | 100,000 | $14.60 | $1.5M | Form 4 |
| Jun 4, 2026 | Manmeet Singh SoniCOO and CFO, Director | Bought | 50,000 | $14.45 | $0.7M | Form 4 |
| Jun 4, 2026 | Robert W DugganCo-Chief Executive Officer, Director, 10% owner | Bought | 100,000 | $14.60 | $1.5M | Form 4 |
| Oct 21, 2025 | Robert W DugganCo-Chief Executive Officer, Director, 10% owner | Bought | 26,680 | $18.74 | $0.5M | Form 4 |
| Oct 21, 2025 | Yu XiaDirector | Bought | 533,617 | $18.74 | $10.0M | Form 4 |
In plain words: Insiders are the people who run or own a big part of the company. Buying with their own money can signal confidence; selling often has personal reasons, like taxes or diversifying.
Can it carry its debts, and how well does it use its money?
Cash, debt and the ratios that show how comfortably Summit Therapeutics Inc. can carry it.
Cash vs debt (incl. leases)
| Fiscal year end | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|
| Cash and short-term investments | $71.8M | $349M | $186M | $412M | $713M |
| Interest coverage | β356.1x | β16.4x | β37.0x | β26.0x | β |
| Current ratio | 3.8x | 16.9x | 9.3x | 10.2x | 9.9x |
| Quick ratio | 3.8x | 16.9x | 9.3x | 10.2x | 9.9x |
| Total assets | $113M | $664M | $203M | $436M | $751M |
| Total liabilities | $30.1M | $538M | $125M | $46.8M | $92.3M |
| Shareholders' equity | $83.3M | $127M | $77.7M | $389M | $659M |
| Net debt (β = net cash) | β | β | β | β | β |
In plain words: What the company owns and what it owes. More cash than debt is a cushion for bad times; a lot of debt leaves less room when business slows down.
After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.
Return on capital, equity and assets (annual)
In plain words: How much profit the business makes on the money put into it. A higher percentage means each dollar invested works harder.
Nine pass/fail tests of profitability, funding and efficiency. 8β9 is strong, 0β2 weak.
| Test | FY18 | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|---|
| Net income is positive | β | β | β | β | β | β |
| Cash from operations is positive | β | β | β | β | β | β |
| Return on assets rose | β | β | β | β | β | β |
| Cash from operations exceeds net income | β | β | β | β | β | β |
| Debt fell relative to assets | β | β | β | β | β | β |
| Current ratio rose | β | β | β | β | β | β |
| Share count didn't rise | β | β | β | β | β | β |
| Gross margin rose | β | β | β | β | β | β |
| Revenue rose relative to assets | β | β | β | β | β | β |
| F-score | β / 3 | β / 4 | 3 / 7 | 1 / 7 | 3 / 7 | β / 6 |
| Accruals ratio | β | β14.8% | β9.6% | β124.1% | β24.8% | β127.5% |
| Altman Z'' | β | β6.67 | 3.76 | β30.02 | 1.90 | β |
In plain words: Nine yes/no tests of financial health, one point each. A green tick is a pass: 7 to 9 points is solid, 0 to 3 is weak.
Every number, year by year.
Amounts in USD. Hover a ratioβs name for its definition.
| Fiscal year | FY18 | FY20 | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|---|---|
| Income statement | |||||||
| Revenue | $57.1M | β | $1.8M | $0.7M | $0.0M | $0.0M | β |
| Research and development | $52.0M | β | $85.4M | $52.0M | $59.5M | $151M | $538M |
| Operating income | $5.4M | β | β$86.2M | β$72.1M | β$610M | β$226M | β |
| Interest expense | $0.6M | β | $0.2M | $4.4M | $16.5M | $8.7M | $0.0M |
| Pretax income | $9.1M | β | β$88.6M | β$78.8M | β$615M | β$221M | β$1.1B |
| Income tax | β$1.8M | β | $0.0M | β | $0.0M | $0.0M | $0.0M |
| Net income | $10.9M | β | β$88.6M | β$78.8M | β$615M | β$221M | β$1.1B |
| Diluted EPS | $0.63 | β | β$0.67 | β$0.41 | β$0.99 | β$0.31 | β$1.44 |
| Diluted shares | 0.02B | β | 0.13B | 0.19B | 0.62B | 0.72B | 0.75B |
| Cash flow | |||||||
| Cash from operations | β$35.1M | β | β$72.6M | β$41.6M | β$76.8M | β$142M | β$323M |
| Capital expenditure | $0.2M | β | $0.3M | $0.6M | $0.1M | $0.1M | $0.7M |
| Free cash flow | β$35.3M | β | β$72.9M | β$42.2M | β$76.9M | β$142M | β$324M |
| Depreciation and amortization | $0.4M | β | $0.3M | $0.3M | $0.2M | $0.1M | $0.1M |
| Stock-based compensation | $6.3M | β | $12.8M | $11.9M | $14.1M | $51.0M | $732M |
| Dividends paid | $0.0M | β | β | β | β | β | β |
| Dividends and buybacks | $0.0M | β | β | β | β | β | β |
| Balance sheet | |||||||
| Cash and short-term investments | $35.2M | $66.4M | $71.8M | $349M | $186M | $412M | $713M |
| Current assets | β | $87.7M | $97.3M | $657M | $190M | $424M | $720M |
| Current liabilities | β | $19.9M | $25.6M | $38.8M | $20.4M | $41.7M | $73.0M |
| Property and equipment, net | β | $0.7M | $0.7M | $0.9M | $0.2M | $0.3M | $1.1M |
| Goodwill | $2.0M | $2.0M | $2.0M | $1.8M | $1.9M | $1.9M | $2.0M |
| Intangible assets | β | $11.5M | $10.4M | $0.0M | $0.0M | $0.0M | β |
| Total assets | β | $102M | $113M | $664M | $203M | $436M | $751M |
| Total liabilities | β | $23.0M | $30.1M | $538M | $125M | $46.8M | $92.3M |
| Preferred stock | β | β | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M |
| Shareholders' equity | $57.6M | $79.5M | $83.3M | $127M | $77.7M | $389M | $659M |
| Margins | |||||||
| Operating margin | 9.4% | β | β4,764.3% | β10,225.4% | β | β | β |
| EBITDA margin | 10.2% | β | β4,746.0% | β10,175.9% | β | β | β |
| Net margin | 19.0% | β | β4,897.8% | β11,174.8% | β | β | β |
| FCF margin | β61.8% | β | β4,029.5% | β5,986.7% | β | β | β |
| Returns | |||||||
| Return on capital employed | β | β | β98.2% | β11.5% | β334.0% | β57.4% | β |
| Return on equity | 18.9% | β | β108.9% | β75.1% | β601.8% | β94.9% | β206.1% |
| Return on assets | β | β | β82.1% | β20.3% | β141.8% | β69.3% | β181.9% |
| Return on tangible equity | 19.5% | β | β125.0% | β63.1% | β811.3% | β57.2% | β164.4% |
| Growth | |||||||
| Revenue growth | β | β | β | β61.0% | β100.0% | β | β |
| Share count change | β | β | β | 46.8% | 220.5% | 16.0% | 4.1% |
| Financial health | |||||||
| Interest coverage | 8.7x | β | β356.1x | β16.4x | β37.0x | β26.0x | β |
| Current ratio | β | 4.4x | 3.8x | 16.9x | 9.3x | 10.2x | 9.9x |
| Quick ratio | β | 4.4x | 3.8x | 16.9x | 9.3x | 10.2x | 9.9x |
| Capital allocation | |||||||
| Capex / revenue | 0.3% | β | 16.9% | 88.5% | β | β | β |
| Stock comp / revenue | 11.0% | β | 707.8% | 1,694.8% | β | β | β |
| Quality scores | |||||||
| Piotroski F-score | β | β | β | 3.0 | 1.0 | 3.0 | β |
| Altman Z'' | β | β | β6.7 | 3.8 | β30.0 | 1.9 | β |
| Accruals ratio | β | β | β14.8% | β9.6% | β124.1% | β24.8% | β127.5% |
In plain words: Every number we have, year by year. Download it as a spreadsheet if you want to dig deeper.
Source: SEC EDGAR XBRL filings (CIK 0001599298). Data updated October 24, 2026. Quarterly fourth quarters are the full year minus the first nine months. For information only β not investment advice. Check the original filings before relying on any figure.