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AC Immune SA

ACIU Nasdaq Pharmaceutical Preparations Financials FY2016โ€“FY2025

Revenue Total sales reported in the income statement.
$4.3M
86.1% vs prior year
Operating margin Operating income as a share of revenue.
โˆ’1,940.0%
1,748.2ย pts
Net income Profit after all expenses, interest and tax.
โˆ’$84.8M
Free cash flow Cash from operations minus capital spending.
โˆ’$84.4M
213.9%
Return on capital After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.
โ€”
Market cap Last close times the latest diluted share count, so it is approximate.
โ€”
P/E Last close divided by diluted earnings per share over the last four quarters.
โ€”
On โˆ’$0.84 EPS (TTM)

What AC Immune SA does

No business description yet.

Legal name
AC Immune SA
Fiscal year ends
December 31, 2025
Latest annual report
20-F ยท Mar 13, 2026
Accession ยท CIK
0001104659-26-027342
0001651625

Revenue and margins

AC Immune SA had $4.3M of revenue in fiscal 2025, down 86.1% on the year before.

Revenue
Revenue
Margins, % of revenue
Gross Operating Net FCF
Margins, % of revenue
Gross Operating Net FCF

Net income and earnings per share

Loss periods are shown in red.

Net income
Net income
Diluted EPS
Diluted EPS

Returns on capital

After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.

Return on capital, equity and assets (annual)
Return on capital Return on equity Return on assets

Cash flow

Free cash flow was โˆ’$84.4M in fiscal 2025, โˆ’1,963.7% of revenue. Cash from operations minus capital spending.

Free cash flow
Free cash flow
Cash from operations vs capital spending
Cash from operations Capital spending
Cash from operations vs capital spending
Cash from operations Capital spending

Dividends, buybacks and share count

AC Immune SA returned โ€” to shareholders in fiscal 2025. The diluted share count rose 1.1%.

Dividends and buybacks
Dividends Buybacks
Diluted shares outstanding (annual)

Balance sheet

Cash, debt and the ratios that show how comfortably AC Immune SA can carry it.

Cash vs debt (incl. leases)
Cash Debt
Fiscal year endFY21FY22FY23FY24FY25
Cash and short-term investments $90.1M$34.2M$93.7M$40.0M$33.8M
Interest coverage โˆ’136.0xโˆ’199.6xโˆ’304.7xโˆ’393.9xโˆ’362.9x
Current ratio 10.1x11.2x9.2x1.7x1.0x
Quick ratio 10.1x11.2x9.2x1.7x1.0x
Total assets $287M$201M$218M$255M$195M
Total liabilities $32.3M$18.4M$26.5M$131M$138M
Shareholders' equity $254M$183M$192M$124M$56.6M
Net debt (โˆ’ = net cash) โ€”โ€”โ€”โ€”โ€”

Insider trades

Open-market purchases and sales by officers, directors and 10% owners, from Form 4 filings. โ€œPlanโ€ marks trades under a pre-arranged Rule 10b5-1 plan.

Bought, 12 months

$0.0M

0 insiders

Sold, 12 months

$0.0M

0 insiders

Of sales under plans

โ€”

$0.0M

No open-market insider trades in the last 12 months.

Piotroski F-score

Nine pass/fail tests of profitability, funding and efficiency. 8โ€“9 is strong, 0โ€“2 weak.

TestFY16FY17FY18FY19FY20FY21FY22FY23FY24FY25
Net income is positive โœ• โœ• โœ• โœ“ โœ• โœ• โœ• โœ• โœ• โœ•
Cash from operations is positive โœ• โœ• โœ• โœ“ โœ• โœ• โœ• โœ• โœ“ โœ•
Return on assets rose โ€” โœ• โœ• โœ“ โœ• โœ• โœ• โœ“ โœ“ โœ•
Cash from operations exceeds net income โœ“ โœ“ โœ“ โœ“ โœ“ โœ“ โœ• โœ• โœ“ โœ“
Debt fell relative to assets โ€” โ€” โ€” โ€” โ€” โ€” โ€” โ€” โ€” โ€”
Current ratio rose โ€” โœ• โœ“ โœ“ โœ• โœ• โœ“ โœ• โœ• โœ•
Share count didn't rise โ€” โœ• โœ• โœ• โœ• โœ• โœ• โœ• โœ• โœ•
Gross margin rose โ€” โ€” โ€” โ€” โ€” โ€” โ€” โ€” โ€” โ€”
Revenue rose relative to assets โ€” โœ• โœ• โœ“ โœ• โœ• โœ“ โœ“ โœ“ โœ•
F-score โ€” / 31 / 72 / 76 / 71 / 71 / 72 / 72 / 74 / 71 / 7
Accruals ratio โˆ’1.0%โˆ’3.0%โˆ’4.2%โˆ’3.9%โˆ’0.9%โˆ’2.9%1.2%3.3%โˆ’56.1%โˆ’0.6%
Altman Z'' 15.5411.1112.1316.8512.288.327.484.13โˆ’3.75โˆ’11.64

10 years of figures

Amounts in USD. Hover a ratioโ€™s name for its definition.

Download CSV
Fiscal yearFY16FY17FY18FY19FY20FY21FY22FY23FY24FY25
Income statement
Revenue $23.6M $20.6M $7.1M $111M $16.4M $0.0M $4.1M $16.5M $31.0M $4.3M
Net interest income $0.0M $0.2M โˆ’$0.3M โˆ’$1.6M โ€” โ€” โ€” โ€” โ€” โ€”
Research and development $26.2M $33.2M $45.3M $50.8M $63.4M $68.1M $63.2M $60.8M $71.1M $67.9M
Operating income โˆ’$10.6M โˆ’$22.9M โˆ’$50.6M $44.8M โˆ’$65.3M โˆ’$86.4M โˆ’$74.2M โˆ’$59.7M โˆ’$59.5M โˆ’$83.4M
Interest expense $0.0M $0.1M $0.3M $1.9M $0.2M $0.6M $0.4M $0.2M $0.2M $0.2M
Pretax income โˆ’$7.2M โˆ’$26.8M โˆ’$52.1M $45.7M โˆ’$66.0M โˆ’$79.9M โˆ’$74.1M โˆ’$60.4M โˆ’$57.8M โˆ’$84.8M
Income tax $0.0M $0.0M $0.0M $0.0M $0.0M $0.0M $0.0M $0.0M $0.0M $0.0M
Net income โˆ’$7.2M โˆ’$26.8M โˆ’$52.1M $45.7M โˆ’$66.0M โˆ’$79.9M โˆ’$74.1M โˆ’$60.4M โˆ’$57.8M โˆ’$84.8M
Diluted EPS โˆ’$0.14 โˆ’$0.47 โˆ’$0.84 $0.64 โˆ’$0.92 โˆ’$1.06 โˆ’$0.89 โˆ’$0.71 โˆ’$0.58 โˆ’$0.84
Diluted shares 0.05B 0.06B 0.06B 0.07B 0.07B 0.07B 0.08B 0.08B 0.10B 0.10B
Cash flow
Cash from operations โˆ’$5.7M โˆ’$22.4M โˆ’$45.1M $55.6M โˆ’$63.4M โˆ’$71.9M โˆ’$77.0M โˆ’$67.2M $74.8M โˆ’$83.3M
Capital expenditure $0.9M $1.8M $1.9M $1.9M $1.8M $2.9M $1.3M $0.9M $0.7M $1.1M
Free cash flow โˆ’$6.6M โˆ’$24.3M โˆ’$47.0M $53.7M โˆ’$65.2M โˆ’$74.8M โˆ’$78.3M โˆ’$68.1M $74.1M โˆ’$84.4M
Stock-based compensation $1.3M $1.6M $2.6M $2.9M $4.4M $4.5M $3.5M $4.9M $6.2M $5.3M
Share buybacks โ€” โ€” $0.0M $0.0M $0.1M $0.0M $0.0M โ€” โ€” โ€”
Dividends and buybacks โ€” โ€” $0.0M $0.0M $0.1M $0.0M $0.0M โ€” โ€” โ€”
Balance sheet
Cash and short-term investments $149M $127M $159M $200M $183M $90.1M $34.2M $93.7M $40.0M $33.8M
Current assets $152M $133M $196M $303M $263M $222M $139M $149M $190M $122M
Current liabilities $9.7M $10.0M $13.3M $18.1M $15.9M $22.0M $12.4M $16.2M $111M $119M
Property and equipment, net $1.1M $2.4M $3.4M $4.1M $5.0M $5.6M $4.6M $4.0M $2.9M $2.5M
Intangible assets โ€” โ€” โ€” โ€” $0.0M $55.3M $54.6M $60.2M $55.6M $63.6M
Total assets $153M $135M $200M $310M $271M $287M $201M $218M $255M $195M
Total liabilities $13.5M $15.6M $19.2M $27.7M $26.4M $32.3M $18.4M $26.5M $131M $138M
Shareholders' equity $140M $120M $180M $282M $245M $254M $183M $192M $124M $56.6M
Margins
Operating margin โˆ’45.0% โˆ’111.3% โˆ’716.9% 40.3% โˆ’397.0% โ€” โˆ’1,800.4% โˆ’362.3% โˆ’191.8% โˆ’1,940.0%
Net margin โˆ’30.6% โˆ’130.4% โˆ’737.1% 41.1% โˆ’401.3% โ€” โˆ’1,798.0% โˆ’366.4% โˆ’186.4% โˆ’1,971.6%
FCF margin โˆ’28.2% โˆ’118.0% โˆ’664.6% 48.3% โˆ’396.8% โ€” โˆ’1,901.1% โˆ’413.5% 239.0% โˆ’1,963.7%
Net interest share of revenue 0.2% 0.9% โˆ’3.9% โˆ’1.4% โ€” โ€” โ€” โ€” โ€” โ€”
Returns
Return on capital employed โˆ’7.4% โˆ’18.3% โˆ’27.2% 15.4% โˆ’25.6% โˆ’32.7% โˆ’39.3% โˆ’29.6% โˆ’41.4% โˆ’111.0%
Return on equity โˆ’5.2% โˆ’20.7% โˆ’34.7% 19.8% โˆ’25.0% โˆ’32.0% โˆ’33.9% โˆ’32.2% โˆ’36.6% โˆ’93.9%
Return on assets โˆ’4.7% โˆ’18.6% โˆ’31.1% 18.0% โˆ’22.7% โˆ’28.6% โˆ’30.4% โˆ’28.8% โˆ’24.4% โˆ’37.7%
Return on tangible equity โˆ’5.2% โˆ’22.4% โˆ’28.9% 16.2% โˆ’26.9% โˆ’40.1% โˆ’57.7% โˆ’45.9% โˆ’84.7% โ€”
Growth
Revenue growth โ€” โˆ’12.7% โˆ’65.7% 1,473.3% โˆ’85.2% โˆ’100.0% โ€” 299.8% 88.3% โˆ’86.1%
Net income growth โ€” โ€” โ€” โ€” โˆ’244.2% โ€” โ€” โ€” โ€” โ€”
EPS growth โ€” โ€” โ€” โ€” โˆ’242.3% โ€” โ€” โ€” โ€” โ€”
FCF growth โ€” โ€” โ€” โ€” โˆ’221.5% โ€” โ€” โ€” โ€” โˆ’213.9%
Share count change โ€” 13.9% 8.3% 15.0% 1.1% 4.2% 11.5% 1.4% 17.7% 1.1%
Financial health
Interest coverage โˆ’1,494.2x โˆ’153.3x โˆ’166.3x 23.5x โˆ’332.9x โˆ’136.0x โˆ’199.6x โˆ’304.7x โˆ’393.9x โˆ’362.9x
Current ratio 15.6x 13.3x 14.7x 16.7x 16.5x 10.1x 11.2x 9.2x 1.7x 1.0x
Quick ratio 15.6x 13.3x 14.7x 16.7x 16.5x 10.1x 11.2x 9.2x 1.7x 1.0x
Capital allocation
Capex / revenue 3.9% 8.9% 26.9% 1.7% 11.1% โ€” 31.5% 5.4% 2.1% 25.2%
Stock comp / revenue 5.7% 7.8% 36.4% 2.6% 26.5% โ€” 84.6% 29.5% 20.0% 123.0%
Payouts / FCF โ€” โ€” โ€” 0.0% โ€” โ€” โ€” โ€” โ€” โ€”
Quality scores
Piotroski F-score โ€” 1.0 2.0 6.0 1.0 1.0 2.0 2.0 4.0 1.0
Altman Z'' 15.5 11.1 12.1 16.9 12.3 8.3 7.5 4.1 โˆ’3.8 โˆ’11.6
Accruals ratio โˆ’1.0% โˆ’3.0% โˆ’4.2% โˆ’3.9% โˆ’0.9% โˆ’2.9% 1.2% 3.3% โˆ’56.1% โˆ’0.6%

Source: SEC EDGAR XBRL filings (CIK 0001651625). Data updated October 24, 2026. Quarterly fourth quarters are the full year minus the first nine months. Filed in CHF under IFRS and converted to US$: income and cash-flow lines at each period's average exchange rate, balance-sheet lines at the period-end rate. For information only โ€” not investment advice. Check the original filings before relying on any figure.

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