Biocryst Pharmaceuticals Inc
BCRX Nasdaq Biological Products, (No Diagnostic Substances) Financials FY2016โFY2025
Last close ยท Oct 23, 2026
$7.65
1.7%What Biocryst Pharmaceuticals Inc does
No business description yet.
- Legal name
- BIOCRYST PHARMACEUTICALS INC
- Fiscal year ends
- December 31, 2025
- Latest annual report
- 10-K ยท Feb 26, 2026
- Accession ยท CIK
- 0001628280-26-012240
0000882796
Revenue and margins
Biocryst Pharmaceuticals Inc had $875M of revenue in fiscal 2025, up 94.1% on the year before.
Net income and earnings per share
Loss periods are shown in red.
Returns on capital
After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.
Cash flow
Free cash flow was $345M in fiscal 2025, 39.4% of revenue. Cash from operations minus capital spending.
Dividends, buybacks and share count
Biocryst Pharmaceuticals Inc returned โ to shareholders in fiscal 2025. The diluted share count rose 5.8%.
Balance sheet
Cash, debt and the ratios that show how comfortably Biocryst Pharmaceuticals Inc can carry it.
| Fiscal year end | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|
| Cash and short-term investments | $508M | $424M | $389M | $321M | $275M |
| Debt incl. finance leases | $298M | $234M | $308M | $319M | $2.8M |
| Net debt / EBITDA | โ | โ | โ | โ | โ0.8x |
| Interest coverage | โ3.0x | โ1.5x | โ1.0x | โ0.0x | 4.3x |
| Current ratio | 5.5x | 4.9x | 3.3x | 2.6x | 2.1x |
| Quick ratio | 5.3x | 4.6x | 3.1x | 2.6x | 2.0x |
| Total assets | $588M | $550M | $517M | $490M | $514M |
| Total liabilities | $695M | $845M | $972M | $966M | $633M |
| Shareholders' equity | โ$107M | โ$295M | โ$456M | โ$476M | โ$119M |
| Net debt (โ = net cash) | โ$209M | โ$190M | โ$81.3M | โ$2.0M | โ$272M |
Insider trades
Open-market purchases and sales by officers, directors and 10% owners, from Form 4 filings. โPlanโ marks trades under a pre-arranged Rule 10b5-1 plan.
Bought, 12 months
$0.0M
0 insiders
Sold, 12 months
$0.0M
0 insiders
Of sales under plans
โ
$0.0M
No open-market insider trades in the last 12 months.
Piotroski F-score
Nine pass/fail tests of profitability, funding and efficiency. 8โ9 is strong, 0โ2 weak.
| Test | FY16 | FY17 | FY18 | FY19 | FY20 | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|---|---|---|---|---|
| Net income is positive | โ | โ | โ | โ | โ | โ | โ | โ | โ | โ |
| Cash from operations is positive | โ | โ | โ | โ | โ | โ | โ | โ | โ | โ |
| Return on assets rose | โ | โ | โ | โ | โ | โ | โ | โ | โ | โ |
| Cash from operations exceeds net income | โ | โ | โ | โ | โ | โ | โ | โ | โ | โ |
| Debt fell relative to assets | โ | โ | โ | โ | โ | โ | โ | โ | โ | โ |
| Current ratio rose | โ | โ | โ | โ | โ | โ | โ | โ | โ | โ |
| Share count didn't rise | โ | โ | โ | โ | โ | โ | โ | โ | โ | โ |
| Gross margin rose | โ | โ | โ | โ | โ | โ | โ | โ | โ | โ |
| Revenue rose relative to assets | โ | โ | โ | โ | โ | โ | โ | โ | โ | โ |
| F-score | โ / 3 | 5 / 9 | 1 / 8 | 4 / 8 | 3 / 9 | 5 / 9 | 4 / 9 | 4 / 9 | 3 / 9 | 7 / 9 |
| Accruals ratio | โ1.9% | โ18.4% | โ5.3% | โ12.0% | โ18.7% | โ9.1% | โ15.0% | โ24.6% | โ7.3% | โ16.6% |
| Altman Z'' | โ23.23 | โ10.93 | โ18.03 | โ16.46 | โ9.26 | โ3.73 | โ5.90 | โ8.05 | โ8.82 | โ2.63 |
10 years of figures
Amounts in USD. Hover a ratioโs name for its definition.
| Fiscal year | FY16 | FY17 | FY18 | FY19 | FY20 | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|---|---|---|---|---|
| Income statement | ||||||||||
| Revenue | $26.4M | $25.2M | $20.7M | $48.8M | $17.8M | $157M | $271M | $331M | $451M | $875M |
| Gross profit | $24.1M | $24.0M | โ | $45.1M | $16.3M | $150M | $264M | $327M | $438M | $856M |
| Research and development | $61.0M | $67.0M | $84.9M | $107M | $123M | $209M | $253M | $217M | $175M | $166M |
| Operating income | โ$48.6M | โ$57.4M | โ$94.2M | โ$99.5M | โ$175M | โ$178M | โ$148M | โ$104M | โ$2.5M | $341M |
| Interest expense | $6.5M | $8.6M | $9.2M | $11.9M | $14.5M | $59.3M | $99.1M | $108M | $98.5M | $78.9M |
| Pretax income | โ | โ | โ | โ$109M | โ$183M | โ$182M | โ$244M | โ$226M | โ$87.0M | $267M |
| Income tax | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $2.3M | $2.7M | $0.3M | $1.9M | $3.5M |
| Net income | โ$55.1M | โ$65.8M | โ$101M | โ$109M | โ$183M | โ$184M | โ$247M | โ$227M | โ$88.9M | $264M |
| Diluted EPS | โ$0.75 | โ$0.78 | โ$0.98 | โ$940.00 | โ$1.09 | โ$1.03 | โ$1.33 | โ$1.18 | โ$0.43 | $1.21 |
| Diluted shares | 0.07B | 0.08B | 0.10B | 0.12B | 0.17B | 0.18B | 0.19B | 0.19B | 0.21B | 0.22B |
| Cash flow | ||||||||||
| Cash from operations | โ$53.4M | โ$41.1M | โ$92.6M | โ$89.6M | โ$135M | โ$142M | โ$162M | โ$95.1M | โ$52.0M | $347M |
| Capital expenditure | $5.3M | $0.3M | $0.4M | $0.3M | $0.5M | $2.4M | $1.4M | $2.2M | $1.1M | $2.5M |
| Free cash flow | โ$58.7M | โ$41.5M | โ$92.9M | โ$89.9M | โ$136M | โ$145M | โ$163M | โ$97.3M | โ$53.1M | $345M |
| Depreciation and amortization | $0.5M | $0.7M | $0.8M | $0.7M | $0.7M | $0.8M | $1.4M | $1.7M | $1.2M | $1.4M |
| Stock-based compensation | $8.5M | $12.6M | $9.4M | $17.7M | $14.8M | $34.6M | $44.7M | $55.6M | $65.4M | $85.1M |
| Balance sheet | ||||||||||
| Cash and short-term investments | $54.7M | $114M | $104M | $136M | $300M | $508M | $424M | $389M | $321M | $275M |
| Total debt | $23.0M | $23.0M | $30.0M | $50.0M | $123M | $298M | $232M | $303M | $315M | $0.0M |
| Finance lease liabilities | โ | โ | โ | โ | โ | โ | $2.6M | $4.4M | $4.0M | $2.8M |
| Current assets | $67.0M | $125M | $114M | $164M | $324M | $566M | $517M | $496M | $422M | $404M |
| Current liabilities | $54.4M | $74.8M | $69.5M | $92.3M | $106M | $104M | $106M | $150M | $160M | $196M |
| Inventory | $0.5M | โ | $1.6M | $0.0M | $7.0M | $15.8M | $27.5M | $28.7M | $8.1M | $5.4M |
| Property and equipment, net | $9.9M | $9.5M | $9.1M | $7.3M | $7.1M | $8.7M | $8.6M | $7.9M | $7.8M | $8.8M |
| Total assets | $89.8M | $178M | $147M | $175M | $335M | $588M | $550M | $517M | $490M | $514M |
| Total liabilities | $88.3M | $94.5M | $97.6M | $137M | $354M | $695M | $845M | $972M | $966M | $633M |
| Preferred stock | $0.0M | โ | โ | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M |
| Shareholders' equity | $1.6M | $83.8M | $49.2M | $38.3M | โ$19.3M | โ$107M | โ$295M | โ$456M | โ$476M | โ$119M |
| Margins | ||||||||||
| Gross margin | 91.3% | 95.5% | โ | 92.4% | 91.3% | 95.4% | 97.6% | 98.6% | 97.3% | 97.8% |
| Operating margin | โ184.4% | โ227.9% | โ456.2% | โ203.7% | โ981.1% | โ113.1% | โ54.8% | โ31.3% | โ0.6% | 39.0% |
| EBITDA margin | โ182.6% | โ225.2% | โ452.5% | โ202.2% | โ976.9% | โ112.6% | โ54.3% | โ30.8% | โ0.3% | 39.1% |
| Net margin | โ209.3% | โ261.2% | โ490.3% | โ223.0% | โ1,026.4% | โ117.1% | โ91.2% | โ68.4% | โ19.7% | 30.2% |
| FCF margin | โ222.8% | โ164.7% | โ450.0% | โ184.1% | โ761.4% | โ92.0% | โ60.3% | โ29.4% | โ11.8% | 39.4% |
| Returns | ||||||||||
| Return on capital employed | โ137.0% | โ55.5% | โ121.8% | โ119.9% | โ76.3% | โ36.7% | โ33.4% | โ28.3% | โ0.8% | 107.2% |
| Return on equity | โ3,494.6% | โ154.2% | โ152.3% | โ248.9% | โ1,925.4% | โ | โ | โ | โ | โ |
| Return on assets | โ61.4% | โ49.1% | โ62.3% | โ67.6% | โ71.7% | โ39.9% | โ43.4% | โ42.5% | โ17.6% | 52.5% |
| Return on tangible equity | โ3,494.6% | โ78.5% | โ205.7% | โ284.7% | โ | โ | โ | โ | โ | โ |
| Growth | ||||||||||
| Revenue growth | โ | โ4.4% | โ18.0% | 136.5% | โ63.5% | 782.4% | 72.3% | 22.4% | 36.0% | 94.1% |
| Share count change | โ | 14.6% | 22.2% | 12.0% | 44.7% | 7.1% | 3.8% | 3.4% | 7.5% | 5.8% |
| Financial health | ||||||||||
| Net debt / EBITDA | โ | โ | โ | โ | โ | โ | โ | โ | โ | โ0.8x |
| Debt / equity | 14.6x | 0.3x | 0.6x | 1.3x | โ | โ | โ | โ | โ | โ |
| Interest coverage | โ7.5x | โ6.7x | โ10.3x | โ8.4x | โ12.1x | โ3.0x | โ1.5x | โ1.0x | โ0.0x | 4.3x |
| Current ratio | 1.2x | 1.7x | 1.6x | 1.8x | 3.1x | 5.5x | 4.9x | 3.3x | 2.6x | 2.1x |
| Quick ratio | 1.2x | 1.7x | 1.6x | 1.8x | 3.0x | 5.3x | 4.6x | 3.1x | 2.6x | 2.0x |
| Capital allocation | ||||||||||
| Capex / revenue | 20.0% | 1.3% | 1.8% | 0.7% | 2.9% | 1.5% | 0.5% | 0.7% | 0.2% | 0.3% |
| Stock comp / revenue | 32.2% | 50.1% | 45.5% | 36.3% | 83.1% | 22.0% | 16.5% | 16.8% | 14.5% | 9.7% |
| Quality scores | ||||||||||
| Piotroski F-score | โ | 5.0 | 1.0 | 4.0 | 3.0 | 5.0 | 4.0 | 4.0 | 3.0 | 7.0 |
| Altman Z'' | โ23.2 | โ10.9 | โ18.0 | โ16.5 | โ9.3 | โ3.7 | โ5.9 | โ8.1 | โ8.8 | โ2.6 |
| Accruals ratio | โ1.9% | โ18.4% | โ5.3% | โ12.0% | โ18.7% | โ9.1% | โ15.0% | โ24.6% | โ7.3% | โ16.6% |
Source: SEC EDGAR XBRL filings (CIK 0000882796). Data updated October 24, 2026. Quarterly fourth quarters are the full year minus the first nine months. For information only โ not investment advice. Check the original filings before relying on any figure.
