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Definium Therapeutics, Inc.

DFTX Nasdaq Medicinal Chemicals & Botanical Products Financials FY2020โ€“FY2025

Last close ยท Oct 23, 2026

$35.67

0.9%
Compare
Revenue Total sales reported in the income statement.
โ€”
vs prior year
Operating margin Operating income as a share of revenue.
โ€”
Net income Profit after all expenses, interest and tax.
โˆ’$184M
Free cash flow Cash from operations minus capital spending.
โ€”
Return on capital After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.
โ€”
Market cap Last close times the latest diluted share count, so it is approximate.
$3.9B
Oct 23 close
P/E Last close divided by diluted earnings per share over the last four quarters.
โ€”
On โˆ’$3.36 EPS (TTM)

What Definium Therapeutics, Inc. does

No business description yet.

Legal name
Definium Therapeutics, Inc.
Fiscal year ends
December 31, 2025
Latest annual report
10-K ยท Feb 26, 2026
Accession ยท CIK
0001193125-26-076742
0001813814

Revenue and margins

Definium Therapeutics, Inc. had โ€” of revenue in fiscal 2025.

Revenue
Revenue
Margins, % of revenue
Gross Operating Net FCF
Margins, % of revenue
Gross Operating Net FCF

Net income and earnings per share

Loss periods are shown in red.

Net income
Net income
Diluted EPS
Diluted EPS

Returns on capital

After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.

Return on capital, equity and assets (annual)
Return on capital Return on equity Return on assets

Cash flow

Free cash flow was โ€” in fiscal 2025, โ€” of revenue. Cash from operations minus capital spending.

Free cash flow
Cash from operations vs capital spending
Cash from operations Capital spending
Cash from operations vs capital spending
Cash from operations Capital spending

Dividends, buybacks and share count

Definium Therapeutics, Inc. returned โ€” to shareholders in fiscal 2025. The diluted share count rose 26.8%.

Dividends and buybacks
Dividends Buybacks
Diluted shares outstanding (annual)

Balance sheet

Cash, debt and the ratios that show how comfortably Definium Therapeutics, Inc. can carry it.

Cash vs debt (incl. leases)
Cash Debt
Fiscal year endFY21FY22FY23FY24FY25
Cash and short-term investments $134M$142M$99.7M$274M$412M
Debt incl. finance leases โ€”โ€”$14.1M$21.9M$40.6M
Debt / equity โ€”โ€”0.2x0.1x0.1x
Interest coverage โ€”โ€”โˆ’102.0xโˆ’45.5xโˆ’30.3x
Current ratio 13.2x8.2x3.2x7.2x6.3x
Quick ratio 13.2x8.2x3.2x7.2x6.3x
Total assets $164M$170M$125M$302M$440M
Total liabilities $12.3M$19.1M$46.4M$60.7M$108M
Shareholders' equity $152M$151M$78.1M$241M$332M
Net debt (โˆ’ = net cash) โ€”โ€”โˆ’$85.6Mโˆ’$252Mโˆ’$371M

Insider trades

Open-market purchases and sales by officers, directors and 10% owners, from Form 4 filings. โ€œPlanโ€ marks trades under a pre-arranged Rule 10b5-1 plan.

Bought, 12 months

$0.0M

0 insiders

Sold, 12 months

$0.0M

0 insiders

Of sales under plans

โ€”

$0.0M

No open-market insider trades in the last 12 months.

Piotroski F-score

Nine pass/fail tests of profitability, funding and efficiency. 8โ€“9 is strong, 0โ€“2 weak.

TestFY20FY21FY22FY23FY24FY25
Net income is positive โœ• โœ• โœ• โœ• โœ• โœ•
Cash from operations is positive โœ• โœ• โœ• โœ• โœ• โœ•
Return on assets rose โ€” โœ• โœ“ โœ• โœ“ โœ•
Cash from operations exceeds net income โœ“ โœ“ โœ“ โœ“ โœ“ โœ“
Debt fell relative to assets โ€” โ€” โ€” โ€” โœ“ โœ•
Current ratio rose โ€” โœ• โœ• โœ• โœ“ โœ•
Share count didn't rise โ€” โœ“ โœ• โœ• โœ• โœ•
Gross margin rose โ€” โ€” โ€” โ€” โ€” โ€”
Revenue rose relative to assets โ€” โœ• โœ“ โœ“ โ€” โ€”
F-score โ€” / 32 / 73 / 72 / 74 / 71 / 7
Accruals ratio โˆ’12.7%โˆ’38.5%โˆ’4.0%โˆ’21.3%โˆ’13.9%โˆ’14.1%
Altman Z'' 15.9111.406.90โˆ’7.122.831.64

6 years of figures

Amounts in USD. Hover a ratioโ€™s name for its definition.

Download CSV
Fiscal yearFY20FY21FY22FY23FY24FY25
Income statement
Revenue โˆ’$0.2M โˆ’$0.4M $1.5M $4.7M โ€” โ€”
Net interest income โˆ’$0.2M โˆ’$0.4M $1.5M $4.7M โ€” โ€”
Research and development $18.6M $34.8M $36.2M $52.1M $65.3M $118M
Operating income โˆ’$33.0M โˆ’$93.9M โˆ’$66.3M โˆ’$93.9M โˆ’$104M โˆ’$166M
Interest expense โ€” โ€” โ€” $0.9M $2.3M $5.5M
Pretax income โˆ’$33.9M โˆ’$94.2M โˆ’$56.8M โˆ’$95.7M โˆ’$109M โˆ’$184M
Income tax โ€” โˆ’$1.2M โ€” โ€” โ€” $0.0M
Net income โˆ’$33.9M โˆ’$93.0M โˆ’$56.8M โˆ’$95.7M โˆ’$109M โˆ’$184M
Net income to common โ€” โ€” โ€” โ€” โˆ’$109M โˆ’$184M
Diluted EPS โˆ’$0.13 โˆ’$3.40 โˆ’$1.84 โˆ’$2.44 โˆ’$1.54 โˆ’$2.06
Diluted shares 0.27B 0.03B 0.03B 0.04B 0.07B 0.09B
Cash flow
Cash from operations โˆ’$23.6M โˆ’$45.8M โˆ’$50.1M โˆ’$64.4M โˆ’$79.1M โˆ’$132M
Stock-based compensation $7.4M $42.7M $13.7M $15.2M $16.9M $20.1M
Acquisitions โ€” $0.3M โ€” โ€” โ€” โ€”
Balance sheet
Cash and short-term investments $80.1M $134M $142M $99.7M $274M $412M
Total debt โ€” โ€” โ€” $14.1M $21.9M $40.6M
Current assets $81.5M $137M $146M $104M $282M $419M
Current liabilities $3.0M $10.4M $17.9M $32.2M $38.8M $66.7M
Goodwill $0.0M $19.9M $19.9M $19.9M $19.9M $19.9M
Intangible assets โ€” $6.9M $3.7M $0.5M $0.0M โ€”
Total assets $81.5M $164M $170M $125M $302M $440M
Total liabilities $5.7M $12.3M $19.1M $46.4M $60.7M $108M
Shareholders' equity $75.9M $152M $151M $78.1M $241M $332M
Margins
Operating margin 20,140.2% 26,143.2% โˆ’4,436.9% โˆ’2,012.6% โ€” โ€”
Net margin 20,693.3% 25,915.3% โˆ’3,799.1% โˆ’2,052.6% โ€” โ€”
Net interest share of revenue 100.0% 100.0% 100.0% 100.0% โ€” โ€”
Returns
Return on capital employed โˆ’42.1% โˆ’61.1% โˆ’43.6% โˆ’101.7% โˆ’39.5% โˆ’44.5%
Return on equity โˆ’44.7% โˆ’81.8% โˆ’37.5% โˆ’83.6% โˆ’68.0% โˆ’64.1%
Return on assets โˆ’41.6% โˆ’75.8% โˆ’34.0% โˆ’65.0% โˆ’50.9% โˆ’49.5%
Return on tangible equity โˆ’44.7% โˆ’74.5% โˆ’44.6% โˆ’165.9% โˆ’49.1% โˆ’58.8%
Growth
Revenue growth โ€” โ€” โ€” 212.0% โ€” โ€”
Share count change โ€” โˆ’89.7% 12.7% 26.9% 79.9% 26.8%
Financial health
Debt / equity โ€” โ€” โ€” 0.2x 0.1x 0.1x
Interest coverage โ€” โ€” โ€” โˆ’102.0x โˆ’45.5x โˆ’30.3x
Current ratio 27.1x 13.2x 8.2x 3.2x 7.2x 6.3x
Quick ratio 27.1x 13.2x 8.2x 3.2x 7.2x 6.3x
Capital allocation
Stock comp / revenue โˆ’4,515.9% โˆ’11,898.6% 916.9% 325.5% โ€” โ€”
Quality scores
Piotroski F-score โ€” 2.0 3.0 2.0 4.0 1.0
Altman Z'' 15.9 11.4 6.9 โˆ’7.1 2.8 1.6
Accruals ratio โˆ’12.7% โˆ’38.5% โˆ’4.0% โˆ’21.3% โˆ’13.9% โˆ’14.1%

Source: SEC EDGAR XBRL filings (CIK 0001813814). Data updated October 24, 2026. Quarterly fourth quarters are the full year minus the first nine months. For information only โ€” not investment advice. Check the original filings before relying on any figure.

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