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Xenon Pharmaceuticals Inc.

XENE Nasdaq Pharmaceutical Preparations Financials FY2016–FY2025

Revenue Total sales reported in the income statement.
$7.5M
vs prior year
Operating margin Operating income as a share of revenue.
βˆ’4,974.3%
Net income Profit after all expenses, interest and tax.
βˆ’$346M
Free cash flow Cash from operations minus capital spending.
βˆ’$280M
Return on capital After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.
β€”
Market cap Last close times the latest diluted share count, so it is approximate.
β€”
P/E Last close divided by diluted earnings per share over the last four quarters.
β€”
On βˆ’$4.74 EPS (TTM)

What Xenon Pharmaceuticals Inc. does

No business description yet.

Legal name
Xenon Pharmaceuticals Inc.
Fiscal year ends
December 31, 2025
Latest annual report
10-K Β· Feb 26, 2026
Accession Β· CIK
0001193125-26-076650
0001582313

Revenue and margins

Xenon Pharmaceuticals Inc. had $7.5M of revenue in fiscal 2025.

Revenue
Revenue
Margins, % of revenue
Gross Operating Net FCF
Margins, % of revenue
Gross Operating Net FCF

Net income and earnings per share

Loss periods are shown in red.

Net income
Net income
Diluted EPS
Diluted EPS

Returns on capital

After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.

Return on capital, equity and assets (annual)
Return on capital Return on equity Return on assets

Cash flow

Free cash flow was βˆ’$280M in fiscal 2025, βˆ’3,732.2% of revenue. Cash from operations minus capital spending.

Free cash flow
Free cash flow
Cash from operations vs capital spending
Cash from operations Capital spending
Cash from operations vs capital spending
Cash from operations Capital spending

Dividends, buybacks and share count

Xenon Pharmaceuticals Inc. returned β€” to shareholders in fiscal 2025. The diluted share count rose 1.7%.

Dividends and buybacks
Dividends Buybacks
Diluted shares outstanding (annual)

Balance sheet

Cash, debt and the ratios that show how comfortably Xenon Pharmaceuticals Inc. can carry it.

Cash vs debt (incl. leases)
Cash Debt
Fiscal year endFY21FY22FY23FY24FY25
Cash and short-term investments $552M$592M$638M$627M$549M
Current ratio 39.0x26.4x23.6x17.8x13.4x
Quick ratio 39.0x26.4x23.6x17.8x13.4x
Total assets $572M$754M$965M$798M$633M
Total liabilities $22.0M$32.6M$36.9M$43.2M$51.4M
Shareholders' equity $550M$721M$928M$755M$582M
Net debt (βˆ’ = net cash) β€”β€”β€”β€”β€”

Insider trades

Open-market purchases and sales by officers, directors and 10% owners, from Form 4 filings. 'Plan' marks trades under a pre-arranged Rule 10b5-1 plan.

Bought, 12 months

$0.0M

0 insiders

Sold, 12 months

$0.0M

0 insiders

Of sales under plans

β€”

$0.0M

No open-market insider trades in the last 12 months.

Piotroski F-score

Nine pass/fail tests of profitability, funding and efficiency. 8–9 is strong, 0–2 weak.

TestFY16FY17FY18FY19FY20FY21FY22FY23FY24FY25
Net income is positive βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ•
Cash from operations is positive βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ•
Return on assets rose β€” βœ• βœ“ βœ“ βœ“ βœ“ βœ• βœ• βœ• βœ•
Cash from operations exceeds net income βœ“ βœ“ βœ• βœ“ βœ• βœ“ βœ“ βœ“ βœ“ βœ“
Debt fell relative to assets β€” β€” βœ“ βœ“ β€” β€” β€” β€” β€” β€”
Current ratio rose β€” βœ• βœ“ βœ• βœ“ βœ“ βœ• βœ• βœ• βœ•
Share count didn't rise β€” βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ•
Gross margin rose β€” β€” β€” β€” β€” β€” β€” β€” β€” β€”
Revenue rose relative to assets β€” βœ• β€” β€” βœ“ βœ• βœ• βœ• βœ• βœ“
F-score β€” / 31 / 73 / 73 / 73 / 73 / 71 / 71 / 71 / 72 / 7
Accruals ratio βˆ’5.1%βˆ’3.5%0.3%βˆ’27.3%11.5%βˆ’2.5%βˆ’3.7%βˆ’3.6%βˆ’6.0%βˆ’9.3%
Altman Z'' 15.38βˆ’7.504.33βˆ’1.229.9729.5624.9926.8817.246.89

10 years of figures

US$ millions unless stated. Hover a ratio's name for its definition.

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Fiscal yearFY16FY17FY18FY19FY20FY21FY22FY23FY24FY25
Income statement
Revenue $1.8M $0.3M β€” $6.8M $32.2M $18.4M $9.4M $0.0M $0.0M $7.5M
Research and development $19.8M $25.6M $23.6M $38.8M $50.5M $75.5M $106M $168M $210M $301M
Operating income βˆ’$24.8M βˆ’$32.6M βˆ’$38.0M βˆ’$42.8M βˆ’$31.3M βˆ’$79.0M βˆ’$129M βˆ’$214M βˆ’$279M βˆ’$373M
Interest expense β€” β€” $1.4M $1.4M $0.5M β€” β€” β€” β€” β€”
Pretax income β€” β€” βˆ’$34.5M βˆ’$41.6M βˆ’$29.1M βˆ’$78.9M βˆ’$125M βˆ’$183M βˆ’$238M βˆ’$345M
Income tax β€” β€” βˆ’$0.0M βˆ’$0.0M βˆ’$0.3M βˆ’$0.0M $0.1M βˆ’$0.3M βˆ’$4.1M $1.0M
Net income βˆ’$23.0M βˆ’$30.7M βˆ’$34.5M βˆ’$41.6M βˆ’$28.8M βˆ’$78.9M βˆ’$125M βˆ’$182M βˆ’$234M βˆ’$346M
Net income to common βˆ’$23.0M βˆ’$30.7M βˆ’$31.6M βˆ’$40.0M βˆ’$28.0M βˆ’$77.1M βˆ’$125M βˆ’$182M βˆ’$234M β€”
Diluted EPS βˆ’$1.48 βˆ’$1.72 βˆ’$1.63 βˆ’$1.54 βˆ’$0.81 βˆ’$1.77 βˆ’$2.06 βˆ’$2.73 βˆ’$3.01 βˆ’$4.36
Diluted shares 0.02B 0.02B 0.02B 0.03B 0.03B 0.04B 0.06B 0.07B 0.08B 0.08B
Cash flow
Cash from operations βˆ’$19.6M βˆ’$28.7M βˆ’$34.7M βˆ’$4.7M βˆ’$48.1M βˆ’$69.5M βˆ’$101M βˆ’$151M βˆ’$181M βˆ’$279M
Capital expenditure $0.3M $0.3M $0.5M $1.2M $2.6M $2.1M $2.9M $5.6M $3.1M $0.8M
Free cash flow βˆ’$19.8M βˆ’$29.0M βˆ’$35.2M βˆ’$6.0M βˆ’$50.8M βˆ’$71.6M βˆ’$104M βˆ’$157M βˆ’$184M βˆ’$280M
Depreciation and amortization $0.9M $0.6M $0.6M $0.4M $0.6M $0.9M $1.4M $2.1M $2.6M $2.5M
Stock-based compensation $2.2M $2.2M $2.6M $2.9M $5.7M $10.0M $20.4M $32.4M $50.7M $53.7M
Balance sheet
Cash and short-term investments $64.1M $43.7M $119M $141M $177M $552M $592M $638M $627M $549M
Total debt β€” $6.8M $15.0M $15.5M β€” β€” β€” β€” β€” β€”
Current assets $65.7M $44.8M $121M $145M $182M $559M $600M $645M $635M $561M
Current liabilities $3.6M $4.1M $4.1M $43.4M $14.8M $14.3M $22.7M $27.3M $35.6M $41.8M
Property and equipment, net $1.4M $1.1M $1.0M $1.7M $3.6M $4.5M $6.5M $9.7M $10.3M $8.7M
Total assets $67.5M $46.1M $122M $148M $189M $572M $754M $965M $798M $633M
Total liabilities $3.6M $10.2M $19.1M $55.7M $17.8M $22.0M $32.6M $36.9M $43.2M $51.4M
Preferred stock β€” β€” $7.7M $7.7M $7.7M $7.7M β€” β€” β€” β€”
Shareholders' equity $63.9M $35.9M $103M $92.0M $171M $550M $721M $928M $755M $582M
Margins
Operating margin βˆ’1,376.4% βˆ’10,474.3% β€” βˆ’627.0% βˆ’97.3% βˆ’428.4% βˆ’1,368.9% β€” β€” βˆ’4,974.3%
EBITDA margin βˆ’1,328.5% βˆ’10,265.6% β€” βˆ’620.7% βˆ’95.3% βˆ’423.5% βˆ’1,354.0% β€” β€” βˆ’4,940.4%
Net margin βˆ’1,275.5% βˆ’9,872.7% β€” βˆ’609.1% βˆ’89.7% βˆ’427.8% βˆ’1,328.9% β€” β€” βˆ’4,612.1%
FCF margin βˆ’1,100.7% βˆ’9,337.9% β€” βˆ’87.2% βˆ’157.8% βˆ’388.1% βˆ’1,101.6% β€” β€” βˆ’3,732.2%
Returns
Return on capital employed βˆ’38.8% βˆ’77.5% βˆ’32.2% βˆ’41.0% βˆ’17.9% βˆ’14.2% βˆ’17.7% βˆ’22.8% βˆ’36.6% βˆ’63.1%
Return on equity βˆ’36.0% βˆ’61.5% βˆ’49.6% βˆ’42.6% βˆ’21.9% βˆ’21.9% βˆ’19.7% βˆ’22.1% βˆ’27.8% βˆ’51.8%
Return on assets βˆ’34.1% βˆ’54.1% βˆ’40.9% βˆ’30.8% βˆ’17.1% βˆ’20.7% βˆ’18.9% βˆ’21.2% βˆ’26.6% βˆ’48.3%
Return on tangible equity βˆ’36.0% βˆ’85.4% βˆ’30.6% βˆ’43.5% βˆ’16.3% βˆ’14.0% βˆ’17.3% βˆ’19.7% βˆ’31.0% βˆ’59.5%
Growth
Revenue growth β€” βˆ’82.8% β€” β€” 371.0% βˆ’42.7% βˆ’48.8% βˆ’100.0% β€” β€”
Share count change β€” 16.2% 7.9% 33.5% 33.2% 26.3% 38.8% 10.5% 16.5% 1.7%
Financial health
Debt / equity β€” 0.2x 0.1x 0.2x β€” β€” β€” β€” β€” β€”
Interest coverage β€” β€” βˆ’27.3x βˆ’29.9x βˆ’64.7x β€” β€” β€” β€” β€”
Current ratio 18.3x 11.0x 29.5x 3.3x 12.3x 39.0x 26.4x 23.6x 17.8x 13.4x
Quick ratio 18.3x 11.0x 29.5x 3.3x 12.3x 39.0x 26.4x 23.6x 17.8x 13.4x
Capital allocation
Capex / revenue 15.5% 101.3% β€” 18.2% 8.2% 11.1% 30.7% β€” β€” 10.7%
Stock comp / revenue 119.9% 719.0% β€” 42.8% 17.6% 54.3% 216.0% β€” β€” 716.1%
Quality scores
Piotroski F-score β€” 1.0 3.0 3.0 3.0 3.0 1.0 1.0 1.0 2.0
Altman Z'' 15.4 βˆ’7.5 4.3 βˆ’1.2 10.0 29.6 25.0 26.9 17.2 6.9
Accruals ratio βˆ’5.1% βˆ’3.5% 0.3% βˆ’27.3% 11.5% βˆ’2.5% βˆ’3.7% βˆ’3.6% βˆ’6.0% βˆ’9.3%

Source: SEC EDGAR XBRL filings (CIK 0001582313). Data updated October 24, 2026. Quarterly fourth quarters are the full year minus the first nine months. For information only β€” not investment advice. Check the original filings before relying on any figure.

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