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Opaleye Management Inc.

10% owner, Grace Therapeutics, Inc.; 10% owner, Alpha Cognition Inc.; 10% owner, Sol-Gel Technologies Ltd.; 10% owner, Eton Pharmaceuticals, Inc.; 10% owner, SANUWAVE Health, Inc.; 10% owner, Harrow, Inc.; 10% owner, Codexis, Inc.

Bought, 12 months
$20.0M
Sold, 12 months
$22.1M
Companies
7
Latest trade
Oct 26, 2026

Companies

Grace Therapeutics, Inc.10% owner +$0.6M Alpha Cognition Inc.10% owner +$8.2M Sol-Gel Technologies Ltd.10% owner +$11.2M Eton Pharmaceuticals, Inc.10% owner −$5.8M SANUWAVE Health, Inc.10% owner +$0.0M −$2.2M Harrow, Inc.10% owner −$9.2M Codexis, Inc.10% owner −$4.9M

Trades

GRCE Bought 66,411 shares at $1.77 $0.1M Oct 26 Form 4
ACOG Bought 14,973 shares at $8.23 $0.1M Oct 23 Form 4
ACOG Bought 17,117 shares at $8.33 $0.1M Oct 22 Form 4
GRCE Bought 21,390 shares at $1.93 $0.0M Oct 22 Form 4
GRCE Bought 4,256 shares at $1.88 $0.0M Oct 19 Form 4
ACOG Bought 14,283 shares at $8.23 $0.1M Oct 16 Form 4
GRCE Bought 36,347 shares at $1.89 $0.1M Oct 16 Form 4
ACOG Bought 22,657 shares at $8.43 $0.2M Oct 15 Form 4
GRCE Bought 23,485 shares at $1.95 $0.0M Oct 15 Form 4
GRCE Bought 11,233 shares at $1.93 $0.0M Oct 14 Form 4
GRCE Bought 7,215 shares at $2.02 $0.0M Oct 12 Form 4
GRCE Bought 5,340 shares at $2.04 $0.0M Oct 9 Form 4
GRCE Bought 2,077 shares at $2.02 $0.0M Oct 8 Form 4
GRCE Bought 1,694 shares at $2.06 $0.0M Oct 5 Form 4
GRCE Bought 20,000 shares at $2.07 $0.0M Oct 2 Form 4
ACOG Bought 19,050 shares at $8.69 $0.2M Oct 1 Form 4
GRCE Bought 38,796 shares at $2.04 $0.1M Oct 1 Form 4
GRCE Bought 7,849 shares at $2.09 $0.0M Sep 29 Form 4
ACOG Bought 13,426 shares at $8.47 $0.1M Sep 25 Form 4
ACOG Bought 18,337 shares at $8.57 $0.2M Sep 24 Form 4
GRCE Bought 5,318 shares at $2.10 $0.0M Sep 23 Form 4
GRCE Bought 9,771 shares at $2.10 $0.0M Sep 21 Form 4
ACOG Bought 80,170 shares at $8.51 $0.7M Sep 16 Form 4
ACOG Bought 3,375 shares at $8.54 $0.0M Sep 15 Form 4
ACOG Bought 40,373 shares at $8.70 $0.4M Sep 14 Form 4
SLGL Bought 1,493 shares at $65.95 $0.1M Sep 11 Form 4
SLGL Bought 1,631 shares at $66.80 $0.1M Sep 10 Form 4
SLGL Bought 3,097 shares at $68.71 $0.2M Sep 9 Form 4
GRCE Bought 5,836 shares at $2.09 $0.0M Sep 9 Form 4
SLGL Bought 3,861 shares at $68.82 $0.3M Sep 8 Form 4
GRCE Bought 9,393 shares at $2.10 $0.0M Sep 8 Form 4
SLGL Bought 3,018 shares at $69.14 $0.2M Sep 4 Form 4
SLGL Bought 900 shares at $68.95 $0.1M Sep 2 Form 4
SLGL Bought 783 shares at $69.52 $0.1M Sep 1 Form 4
SLGL Bought 5,217 shares at $68.28 $0.4M Aug 31 Form 4
SLGL Bought 35,113 shares at $69.32 $2.4M Aug 28 Form 4
GRCE Bought 11,608 shares at $2.09 $0.0M Aug 14 Form 4
SLGL Bought 951 shares at $71.50 $0.1M Aug 12 Form 4
ACOG Bought 50,000 shares at $8.00 $0.4M Aug 3 Form 4
ACOG Bought 2,900 shares at $7.92 $0.0M Jul 31 Form 4
ACOG Bought 130 shares at $7.90 $0.0M Jul 24 Form 4
ACOG Bought 49,849 shares at $7.80 $0.4M Jul 23 Form 4
ACOG Bought 150,237 shares at $7.83 $1.2M Jul 22 Form 4
ETON Sold 28,315 shares at $37.54 $1.1M Jul 14 Form 4
SLGL Bought 920 shares at $73.43 $0.1M Jul 14 Form 4
SLGL Bought 775 shares at $73.89 $0.1M Jul 13 Form 4
SLGL Bought 229 shares at $73.95 $0.0M Jul 10 Form 4
SLGL Bought 300 shares at $73.69 $0.0M Jul 8 Form 4
ETON Sold 26,685 shares at $38.37 $1.0M Jul 7 Form 4
ETON Sold 10,000 shares at $38.00 $0.4M Jul 6 Form 4
ETON Sold 90,000 shares at $37.39 $3.4M Jul 2 Form 4
SLGL Bought 1,400 shares at $71.97 $0.1M Jul 2 Form 4
SLGL Bought 312 shares at $71.99 $0.0M Jul 1 Form 4
ACOG Bought 152,336 shares at $6.40 $1.0M Jun 26 Form 4
ACOG Bought 197 shares at $6.50 $0.0M Jun 25 Form 4
ACOG Bought 4,550 shares at $5.99 $0.0M Jun 15 Form 4
ACOG Bought 273 shares at $5.93 $0.0M Jun 12 Form 4
ACOG Bought 2,862 shares at $5.91 $0.0M Jun 11 Form 4
ACOG Bought 5,872 shares at $5.99 $0.0M Jun 10 Form 4
ACOG Bought 24,856 shares at $5.98 $0.1M Jun 9 Form 4
ACOG Bought 10,054 shares at $5.83 $0.1M Jun 5 Form 4
ACOG Bought 70,577 shares at $5.90 $0.4M May 29 Form 4
ACOG Bought 2,000 shares at $5.83 $0.0M May 28 Form 4
ACOG Bought 1,161 shares at $5.73 $0.0M May 27 Form 4
ACOG Bought 15,945 shares at $5.70 $0.1M May 21 Form 4
SLGL Bought 1,563 shares at $64.43 $0.1M May 20 Form 4
ACOG Bought 8,431 shares at $5.89 $0.0M May 20 Form 4
ACOG Bought 17,395 shares at $5.69 $0.1M May 18 Form 4
ACOG Bought 16,648 shares at $5.83 $0.1M May 15 Form 4
SLGL Bought 1,937 shares at $66.87 $0.1M May 13 Form 4
SLGL Bought 1,500 shares at $67.98 $0.1M May 12 Form 4
SNWV Sold 10,581 shares at $16.11 $0.2M May 1 Form 4
SNWV Sold 25,000 shares at $16.15 $0.4M Apr 30 Form 4
SNWV Sold 24,360 shares at $17.25 $0.4M Apr 29 Form 4
SNWV Sold 46,288 shares at $18.47 $0.9M Apr 28 Form 4
SNWV Sold 202 shares at $20.50 $0.0M Apr 21 Form 4
SNWV Sold 16,267 shares at $20.46 $0.3M Apr 17 Form 4
ACOG Bought 1,850 shares at $4.99 $0.0M Mar 30 Form 4
ACOG Bought 10,000 shares at $5.08 $0.1M Mar 27 Form 4
ACOG Bought 7,319 shares at $5.28 $0.0M Mar 26 Form 4
ACOG Bought 8,581 shares at $5.43 $0.0M Mar 25 Form 4
SLGL Bought 39,665 shares at $72.00 $2.9M Mar 24 Form 4
ACOG Bought 4,182 shares at $5.59 $0.0M Mar 24 Form 4
ACOG Bought 2,094 shares at $5.71 $0.0M Mar 19 Form 4
ACOG Bought 2,481 shares at $5.75 $0.0M Mar 18 Form 4
ACOG Bought 1,331 shares at $5.78 $0.0M Mar 16 Form 4
ACOG Bought 7,358 shares at $5.75 $0.0M Mar 13 Form 4
ACOG Bought 5,708 shares at $5.85 $0.0M Mar 12 Form 4
ACOG Bought 2,179 shares at $5.85 $0.0M Mar 9 Form 4
ACOG Bought 1,900 shares at $5.80 $0.0M Mar 6 Form 4
ACOG Bought 47,023 shares at $5.80 $0.3M Mar 5 Form 4
HROW Sold 138,263 shares at $39.67 $5.5M Mar 4 Form 4
ACOG Bought 19,795 shares at $5.81 $0.1M Mar 4 Form 4
HROW Sold 60,309 shares at $39.15 $2.4M Mar 3 Form 4
ACOG Bought 51,411 shares at $5.75 $0.3M Mar 3 Form 4
ACOG Bought 20,000 shares at $5.80 $0.1M Mar 2 Form 4
HROW Sold 5,000 shares at $54.18 $0.3M Feb 27 Form 4
ACOG Bought 3,638 shares at $5.99 $0.0M Feb 27 Form 4
ACOG Bought 590 shares at $5.99 $0.0M Feb 26 Form 4
ACOG Bought 58,591 shares at $5.80 $0.3M Feb 24 Form 4
ACOG Bought 100,000 shares at $5.89 $0.6M Feb 23 Form 4
ACOG Bought 12,819 shares at $5.84 $0.1M Feb 20 Form 4
SLGL Bought 291 shares at $63.00 $0.0M Feb 13 Form 4
SLGL Bought 100 shares at $58.00 $0.0M Feb 2 Form 4
SLGL Bought 100 shares at $57.05 $0.0M Jan 27 Form 4
SLGL Bought 1,151 shares at $55.98 $0.1M Jan 23 Form 4
SLGL Bought 2,173 shares at $56.57 $0.1M Jan 22 Form 4
HROW Sold 20,000 shares at $53.35 $1.1M Jan 6 Form 4
SLGL Bought 198 shares at $42.98 $0.0M Jan 5 Form 4
SLGL Bought 2,394 shares at $41.92 $0.1M Jan 2 Form 4
SLGL Bought 22,497 shares at $41.99 $0.9M Dec 31 Form 4
SLGL Bought 35,169 shares at $41.99 $1.5M Dec 30 Form 4
SLGL Bought 8,638 shares at $41.85 $0.4M Dec 29 Form 4
SLGL Bought 1,626 shares at $41.68 $0.1M Dec 26 Form 4
SLGL Bought 260 shares at $41.66 $0.0M Dec 23 Form 4
SLGL Bought 1,019 shares at $41.15 $0.0M Dec 22 Form 4
SLGL Bought 2,735 shares at $40.37 $0.1M Dec 17 Form 4
SLGL Bought 87 shares at $40.00 $0.0M Dec 12 Form 4
SLGL Bought 300 shares at $39.78 $0.0M Dec 8 Form 4
SLGL Bought 444 shares at $39.50 $0.0M Dec 5 Form 4
SLGL Bought 2,524 shares at $37.81 $0.1M Dec 3 Form 4
CDXS Sold 253,533 shares at $1.67 $0.4M Dec 1 Form 4
SLGL Bought 4,340 shares at $37.37 $0.2M Dec 1 Form 4
CDXS Sold 107,490 shares at $1.75 $0.2M Nov 28 Form 4
CDXS Sold 153,318 shares at $1.74 $0.3M Nov 26 Form 4
SLGL Bought 943 shares at $40.00 $0.0M Nov 26 Form 4
SLGL Bought 6 shares at $35.50 $0.0M Nov 24 Form 4
SLGL Bought 5,784 shares at $35.83 $0.2M Nov 20 Form 4
CDXS Sold 1,082,459 shares at $1.94 $2.1M Nov 12 Form 4
CDXS Sold 548,211 shares at $1.80 $1.0M Nov 11 Form 4
CDXS Sold 208,318 shares at $1.73 $0.4M Nov 10 Form 4
CDXS Sold 306,682 shares at $1.70 $0.5M Nov 7 Form 4
SNWV Bought 1,267 shares at $30.28 $0.0M Oct 6 Form 4

Open-market trades from SEC Form 4 only: no grants, option exercises or gifts. People are matched by the name on their filings, so two people with the same name share this page. For information only — not investment advice.

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