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Alector, Inc.

ALEC Nasdaq Biological Products, (No Diagnostic Substances) Financials FY2017–FY2025

Alector, Inc. had $21.0M of revenue in fiscal 2025, down 79.1% on the year before. Over five years, revenue changed βˆ’0.1% a year on average.

Download report 3-page PDF: the company, its results and charts with peers.

Last close Β· Oct 23, 2026

$1.83

0.0%

What Alector, Inc. does

ALEC Β· Biological Products, (No Diagnostic Substances)

No business description yet.

Legal name
Alector, Inc.
Fiscal year ends
December 31, 2025
Latest annual report
10-K Β· Feb 25, 2026
Accession Β· CIK
0001193125-26-071593
0001653087

KIRA’s summary AI analyst

Hi! I read Alector, Inc.’s latest annual report (fiscal 2025). Here is what stands out:

1 strength 5 to watch

1.Sales and profit

See section β†’
  • Alector, Inc. had $21.0M of revenue in fiscal 2025, down 79.1% on the year before. Over five years, revenue changed βˆ’0.1% a year on average.
  • Its operating margin was βˆ’741.3%, down 597.1Β pts: of every 100 in sales, about βˆ’741 is left after running the business.
  • Alector, Inc. lost $143M in fiscal 2025.

Alector, Inc. in 30 seconds

Good So-so Weak

Weak

Are sales growing?

βˆ’79.1%

No. Sales fell 79.1% last year.

Weak

Does it make a profit?

βˆ’679.2%

No. It lost money last year.

Weak

Does profit turn into cash?

βˆ’874.7%

No. It spent more cash than it brought in.

Weak

How healthy are the accounts?

1 / 8

Weak. It passes 1 of 8 health tests.

For information

How is the share priced?

β€”

No P/E: it made no profit over the last four quarters.

Rules of thumb on reported numbers. A starting point, not a recommendation.

Key numbers, fiscal 2025

Market cap Last close times the latest diluted share count, so it is approximate.
$204M
Oct 23 close
P/E Last close divided by diluted earnings per share over the last four quarters.
β€”
On βˆ’$1.10 EPS (TTM)

Revenue

Total sales reported in the income statement.

KIRA Β· Alector, Inc. had $21.0M of revenue in fiscal 2025, down 79.1% on the year before. Over five years, revenue changed βˆ’0.1% a year on average.

See the full section β†’

Operating margin

Operating income as a share of revenue.

KIRA Β· Its operating margin was βˆ’741.3%, down 597.1Β pts: of every 100 in sales, about βˆ’741 is left after running the business.

See the full section β†’

Net income

Profit after all expenses, interest and tax.

KIRA Β· Alector, Inc. lost $143M in fiscal 2025.

See the full section β†’

Free cash flow

Cash from operations minus capital spending.

KIRA Β· Free cash flow was βˆ’$184M in fiscal 2025, βˆ’874.7% of revenue.

See the full section β†’

Return on capital

After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.

Sales and profit

Is it selling more, and how much does it keep?

Results dates

In plain words: Every quarter, companies publish how much they sold and earned. These are the days Alector, Inc. did it, and the next one. Share prices often move a lot on those days.

Next results

November 5, 2026

Thursday Β· in 11 days

Time
Time not announced
Covers
Period ended Sep 30, 2026
Expected EPS
βˆ’$0.23
Source
Earnings calendar

No past results dates on file yet.

Revenue and margins

KIRA Β· Alector, Inc. had $21.0M of revenue in fiscal 2025, down 79.1% on the year before. Over five years, revenue changed βˆ’0.1% a year on average. Its operating margin was βˆ’741.3%, down 597.1Β pts: of every 100 in sales, about βˆ’741 is left after running the business.

In plain words: Revenue is all the money customers paid. The margins show how many cents of each dollar of sales are left over at each step: after making the product (gross), after running the business (operating) and after everything, tax included (net).

Revenue
Revenue
Margins, % of revenue
Gross Operating Net FCF
Margins, % of revenue
Gross Operating Net FCF

Net income and earnings per share

KIRA Β· Alector, Inc. lost $143M in fiscal 2025.

Loss periods are shown in red.

In plain words: Net income is the profit left after every cost and tax. Earnings per share (EPS) splits that profit across every share, so it shows what one share earned.

Net income
Net income
Diluted EPS
Diluted EPS

Cash and shareholders

How much cash comes in, and where does it go?

Cash flow

KIRA Β· Free cash flow was βˆ’$184M in fiscal 2025, βˆ’874.7% of revenue.

Cash from operations minus capital spending.

In plain words: Profit on paper is not the same as cash in the bank. Free cash flow is the cash left after paying to run and maintain the business: the money it can hand back to shareholders, save or invest.

Free cash flow
Free cash flow
Cash from operations vs capital spending
Cash from operations Capital spending
Cash from operations vs capital spending
Cash from operations Capital spending

Dividends, buybacks and share count

In plain words: Companies hand cash back in two ways: dividends (cash paid to shareholders) and buybacks (buying back their own shares, so each remaining share owns a bigger slice).

Dividends and buybacks
Dividends Buybacks
Diluted shares outstanding (annual)

Insider trades

KIRA Β· No open-market insider trades in the last 12 months.

Open-market purchases and sales by officers, directors and 10% owners, from Form 4 filings. β€œPlan” marks trades under a pre-arranged Rule 10b5-1 plan.

In plain words: Insiders are the people who run or own a big part of the company. Buying with their own money can signal confidence; selling often has personal reasons, like taxes or diversifying.

Bought, 12 months

$0.0M

0 insiders

Sold, 12 months

$0.0M

0 insiders

Of sales under plans

β€”

$0.0M

No open-market insider trades in the last 12 months.

Financial health

Can it carry its debts, and how well does it use its money?

Balance sheet

KIRA Β· Alector, Inc. has $246M more cash than debt.

Cash, debt and the ratios that show how comfortably Alector, Inc. can carry it.

In plain words: What the company owns and what it owes. More cash than debt is a cushion for bad times; a lot of debt leaves less room when business slows down.

Cash vs debt (incl. leases)
Cash Debt
Fiscal year endFY21FY22FY23FY24FY25
Cash and short-term investments $735M$713M$549M$413M$256M
Debt incl. finance leases β€”β€”$0.0M$10.0M$10.4M
Debt / equity β€”β€”0.0x0.1x0.3x
Current ratio 5.4x7.7x3.2x3.4x3.8x
Quick ratio 5.4x7.7x3.2x3.4x3.8x
Total assets $815M$788M$622M$468M$293M
Total liabilities $514M$573M$488M$342M$263M
Shareholders' equity $301M$214M$134M$127M$30.6M
Net debt (βˆ’ = net cash) β€”β€”βˆ’$549Mβˆ’$403Mβˆ’$246M

Returns on capital

After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.

In plain words: How much profit the business makes on the money put into it. A higher percentage means each dollar invested works harder.

Return on capital, equity and assets (annual)
Return on capital Return on equity Return on assets

Piotroski F-score

KIRA Β· Alector, Inc. passes 1 of 8 financial health tests (Piotroski F-score).

Nine pass/fail tests of profitability, funding and efficiency. 8–9 is strong, 0–2 weak.

In plain words: Nine yes/no tests of financial health, one point each. A green tick is a pass: 7 to 9 points is solid, 0 to 3 is weak.

TestFY17FY18FY19FY20FY21FY22FY23FY24FY25
Net income is positive βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ•
Cash from operations is positive βœ• βœ“ βœ• βœ• βœ“ βœ• βœ• βœ• βœ•
Return on assets rose β€” β€” βœ• βœ• βœ“ βœ• βœ• βœ• βœ•
Cash from operations exceeds net income βœ“ βœ“ βœ“ βœ“ βœ“ βœ“ βœ• βœ• βœ•
Debt fell relative to assets β€” β€” β€” β€” β€” β€” β€” βœ• βœ•
Current ratio rose β€” β€” βœ• βœ“ βœ• βœ“ βœ• βœ“ βœ“
Share count didn't rise β€” βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ•
Gross margin rose β€” β€” β€” β€” β€” β€” β€” β€” β€”
Revenue rose relative to assets β€” β€” βœ• βœ• βœ“ βœ• βœ• βœ“ βœ•
F-score β€” / 3β€” / 41 / 72 / 74 / 72 / 70 / 72 / 81 / 8
Accruals ratio β€”βˆ’58.3%βˆ’1.7%βˆ’5.2%βˆ’51.4%βˆ’14.1%7.6%20.3%10.8%
Altman Z'' β€”2.231.970.603.432.09βˆ’0.98βˆ’3.26βˆ’9.85

All figures

Every number, year by year.

9 years of figures

Amounts in USD. Hover a ratio’s name for its definition.

In plain words: Every number we have, year by year. Download it as a spreadsheet if you want to dig deeper.

Download CSV
Fiscal yearFY17FY18FY19FY20FY21FY22FY23FY24FY25
Income statement
Revenue $3.7M $27.7M $21.2M $21.1M $207M $134M $97.1M $101M $21.0M
Research and development $29.9M $73.0M $101M $157M $189M $210M $192M $186M $123M
Operating income βˆ’$32.7M βˆ’$57.3M βˆ’$114M βˆ’$195M βˆ’$37.4M βˆ’$138M βˆ’$152M βˆ’$145M βˆ’$156M
Pretax income β€” β€” β€” βˆ’$190M βˆ’$36.3M βˆ’$130M βˆ’$125M βˆ’$119M βˆ’$143M
Income tax β€” β€” $0.0M $0.0M $0.0M $3.3M $5.2M $0.1M $0.2M
Net income βˆ’$32.5M βˆ’$52.2M βˆ’$105M βˆ’$190M βˆ’$36.3M βˆ’$133M βˆ’$130M βˆ’$119M βˆ’$143M
Diluted EPS βˆ’$3.55 βˆ’$4.62 βˆ’$1.71 βˆ’$2.45 βˆ’$0.45 βˆ’$1.62 βˆ’$1.56 βˆ’$1.23 βˆ’$1.39
Diluted shares 0.01B 0.01B 0.06B 0.08B 0.08B 0.08B 0.08B 0.10B 0.10B
Cash flow
Cash from operations βˆ’$17.8M $127M βˆ’$99.3M βˆ’$167M $299M βˆ’$20.3M βˆ’$184M βˆ’$230M βˆ’$184M
Capital expenditure $0.8M $1.9M $15.3M $5.0M $3.2M $4.1M $2.4M $1.3M $0.0M
Free cash flow βˆ’$18.6M $126M βˆ’$115M βˆ’$172M $295M βˆ’$24.4M βˆ’$187M βˆ’$231M βˆ’$184M
Depreciation and amortization $0.7M $1.0M $3.8M $5.9M $6.3M $5.7M $5.7M $5.4M $5.7M
Stock-based compensation $5.4M $6.9M $16.3M $30.5M $40.8M $46.1M $42.8M $39.5M $26.7M
Balance sheet
Cash and short-term investments $32.5M $290M $353M $413M $735M $713M $549M $413M $256M
Total debt β€” β€” β€” β€” β€” β€” $0.0M $10.0M $10.4M
Current assets β€” $293M $357M $422M $750M $726M $566M $425M $266M
Current liabilities β€” $47.9M $62.0M $68.1M $140M $93.8M $178M $125M $69.5M
Property and equipment, net β€” $10.9M $33.9M $30.2M $27.3M $25.5M $21.9M $17.1M $10.8M
Total assets β€” $308M $422M $488M $815M $788M $622M $468M $293M
Total liabilities β€” $195M $227M $221M $514M $573M $488M $342M $263M
Shareholders' equity βˆ’$52.0M βˆ’$97.4M $195M $268M $301M $214M $134M $127M $30.6M
Margins
Operating margin βˆ’874.9% βˆ’207.0% βˆ’539.2% βˆ’925.1% βˆ’18.0% βˆ’103.2% βˆ’156.3% βˆ’144.2% βˆ’741.3%
EBITDA margin βˆ’856.7% βˆ’203.3% βˆ’521.4% βˆ’897.3% βˆ’15.0% βˆ’98.9% βˆ’150.4% βˆ’138.8% βˆ’714.1%
Net margin βˆ’869.6% βˆ’188.8% βˆ’496.7% βˆ’901.6% βˆ’17.5% βˆ’99.8% βˆ’134.3% βˆ’118.4% βˆ’679.2%
FCF margin βˆ’497.2% 453.7% βˆ’540.0% βˆ’814.1% 142.6% βˆ’18.3% βˆ’192.1% βˆ’229.9% βˆ’874.7%
Returns
Return on capital employed β€” βˆ’22.0% βˆ’31.8% βˆ’46.5% βˆ’5.5% βˆ’19.9% βˆ’34.2% βˆ’42.2% βˆ’69.7%
Return on equity β€” β€” βˆ’216.5% βˆ’82.3% βˆ’12.8% βˆ’51.8% βˆ’74.8% βˆ’91.2% βˆ’181.6%
Return on assets β€” βˆ’16.9% βˆ’28.9% βˆ’41.8% βˆ’5.6% βˆ’16.6% βˆ’18.5% βˆ’21.8% βˆ’37.5%
Return on tangible equity β€” β€” βˆ’54.1% βˆ’71.1% βˆ’12.1% βˆ’62.2% βˆ’97.2% βˆ’93.9% βˆ’466.3%
Growth
Revenue growth β€” 641.0% βˆ’23.3% βˆ’0.6% 881.5% βˆ’35.5% βˆ’27.3% 3.6% βˆ’79.1%
FCF growth β€” β€” βˆ’191.2% β€” β€” βˆ’108.3% β€” β€” β€”
Share count change β€” 23.6% 446.2% 26.0% 3.4% 2.6% 1.5% 15.4% 6.6%
Financial health
Debt / equity β€” β€” β€” β€” β€” β€” 0.0x 0.1x 0.3x
Current ratio β€” 6.1x 5.8x 6.2x 5.4x 7.7x 3.2x 3.4x 3.8x
Quick ratio β€” 6.1x 5.8x 6.2x 5.4x 7.7x 3.2x 3.4x 3.8x
Capital allocation
Capex / revenue 21.4% 6.8% 71.9% 23.9% 1.6% 3.1% 2.5% 1.2% 0.2%
Stock comp / revenue 143.3% 25.0% 76.7% 144.7% 19.7% 34.5% 44.1% 39.2% 126.7%
Quality scores
Piotroski F-score β€” β€” 1.0 2.0 4.0 2.0 0.0 2.0 1.0
Altman Z'' β€” 2.2 2.0 0.6 3.4 2.1 βˆ’1.0 βˆ’3.3 βˆ’9.9
Accruals ratio β€” βˆ’58.3% βˆ’1.7% βˆ’5.2% βˆ’51.4% βˆ’14.1% 7.6% 20.3% 10.8%

Source: SEC EDGAR XBRL filings (CIK 0001653087). Data updated October 24, 2026. Quarterly fourth quarters are the full year minus the first nine months. For information only β€” not investment advice. Check the original filings before relying on any figure.

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