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AstraZeneca

AZN NYSE Pharmaceuticals Financials FY2016–FY2025

AstraZeneca had $58.7B of revenue in fiscal 2025, up 8.6% on the year before. Over five years, revenue changed +17.2% a year on average.

Last close · Oct 26, 2026

$172.06

0.3%

What AstraZeneca does

AZN · Pharmaceuticals

From its latest annual report

No business description yet.

Filing details

Legal name
ASTRAZENECA PLC
Fiscal year ends
December 31, 2025
Latest annual report
—
Accession · CIK
0001104659-26-019130 · 0000901832

Earnings calendar · AstraZeneca

Every quarter, companies publish how much they sold and earned. These are the days AstraZeneca did it, and the next one. Share prices often move a lot on those days.

Next results

October 30, 2026

Friday · in 4 days

Time
Before the market opens
Covers
Period ended Sep 30, 2026
Expected EPS
$2.16
Source
Earnings calendar
See who else reports that week →
Date Results for Time Source
Feb 24, 2026 Period ended Dec 31, 2025 After the market closes 20-F ↗
Feb 18, 2025 Period ended Dec 31, 2024 After the market closes 20-F ↗
Feb 20, 2024 Period ended Dec 31, 2023 After the market closes 20-F ↗
Feb 21, 2023 Period ended Dec 31, 2022 After the market closes 20-F ↗
Feb 22, 2022 Period ended Dec 31, 2021 After the market closes 20-F ↗
Feb 16, 2021 Period ended Dec 31, 2020 Before the market opens 20-F ↗
Mar 3, 2020 Period ended Dec 31, 2019 After the market closes 20-F ↗

From SEC filings: the results press release (8-K) or, without one, the quarterly or annual report.

KIRA’s summary AI analyst

Hi! I read AstraZeneca’s latest annual report (fiscal 2025). Here is what stands out:

6 strengths

1.Sales and profit

See section →
  • AstraZeneca had $58.7B of revenue in fiscal 2025, up 8.6% on the year before. Over five years, revenue changed +17.2% a year on average.
  • Its operating margin was 23.4%, up 4.9 pts: of every 100 in sales, about 23 is left after running the business.
  • AstraZeneca made $10.2B of net profit in fiscal 2025. From fiscal 2016 to 2025, diluted EPS grew 10.1% a year.

2.Cash and shareholders

See section →
  • Free cash flow was $11.8B in fiscal 2025, 20.0% of revenue.
  • AstraZeneca returned $5.5B to shareholders in fiscal 2025, 47% of free cash flow. The diluted share count fell 0.1%.
  • In the last 12 months, insiders bought $0.0M and sold $2.2M of shares on the open market.

3.Financial health

See section →
  • AstraZeneca owes $22.1B more than it holds in cash.
  • Its return on capital was 16.8%: every 100 invested in the business earned about 17 in a year.
  • AstraZeneca passes 9 of 9 financial health tests (Piotroski F-score).

AstraZeneca in 30 seconds

Good So-so Weak

Good

Are sales growing?

+8.6%

Yes. Sales grew 8.6% last year.

Good

Does it make a profit?

17.4%

Yes. It keeps 17.4% of every sale as profit.

Good

Does profit turn into cash?

20.0%

Yes. 20.0% of sales ends up as free cash.

Good

How healthy are the accounts?

9 / 9

Solid. It passes 9 of 9 health tests.

Rules of thumb on reported numbers. A starting point, not a recommendation.

Key numbers, fiscal 2025

Market cap Last close times the latest diluted share count, so it is approximate.
$268.8B
Oct 26 close
P/E Last close divided by diluted earnings per share over the last four quarters.
—

Revenue

Total sales reported in the income statement.

KIRA · AstraZeneca had $58.7B of revenue in fiscal 2025, up 8.6% on the year before. Over five years, revenue changed +17.2% a year on average.

See the full section →

Operating margin

Operating income as a share of revenue.

KIRA · Its operating margin was 23.4%, up 4.9 pts: of every 100 in sales, about 23 is left after running the business.

See the full section →

Net income

Profit after all expenses, interest and tax.

KIRA · AstraZeneca made $10.2B of net profit in fiscal 2025. From fiscal 2016 to 2025, diluted EPS grew 10.1% a year.

See the full section →

Free cash flow

Cash from operations minus capital spending.

KIRA · Free cash flow was $11.8B in fiscal 2025, 20.0% of revenue.

See the full section →

Return on capital

After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.

KIRA · Its return on capital was 16.8%: every 100 invested in the business earned about 17 in a year.

See the full section →

About these figures. AstraZeneca is a foreign company: it files an annual report on Form 20-F, prepared under international accounting standards (IFRS), instead of a 10-K, and no quarterly reports, so this page has fiscal years only. Its shares trade in the US as American depositary shares (ADSs), and one ADS can stand for several ordinary shares, so per-share figures are per ordinary share and the page has no market value, P/E or valuation model.

Sales and profit

Is it selling more, and how much does it keep?

Revenue and margins

KIRA · AstraZeneca had $58.7B of revenue in fiscal 2025, up 8.6% on the year before. Over five years, revenue changed +17.2% a year on average. Its operating margin was 23.4%, up 4.9 pts: of every 100 in sales, about 23 is left after running the business.

In plain words: Revenue is all the money customers paid. The margins show how many cents of each dollar of sales are left over at each step: after making the product (gross), after running the business (operating) and after everything, tax included (net).

Revenue

Margins, % of revenue

Gross Operating Net FCF

Net income and earnings per share

KIRA · AstraZeneca made $10.2B of net profit in fiscal 2025. From fiscal 2016 to 2025, diluted EPS grew 10.1% a year.

Loss periods are shown in red.

In plain words: Net income is the profit left after every cost and tax. Earnings per share (EPS) splits that profit across every share, so it shows what one share earned.

Net income

Diluted EPS

Cash and shareholders

How much cash comes in, and where does it go?

Cash flow

KIRA · Free cash flow was $11.8B in fiscal 2025, 20.0% of revenue.

Cash from operations minus capital spending.

In plain words: Profit on paper is not the same as cash in the bank. Free cash flow is the cash left after paying to run and maintain the business: the money it can hand back to shareholders, save or invest.

Free cash flow

Cash from operations vs capital spending

Cash from operations Capital spending

Dividends, buybacks and share count

KIRA · AstraZeneca returned $5.5B to shareholders in fiscal 2025, 47% of free cash flow. The diluted share count fell 0.1%.

In plain words: Companies hand cash back in two ways: dividends (cash paid to shareholders) and buybacks (buying back their own shares, so each remaining share owns a bigger slice).

Dividends and buybacks

Dividends Buybacks

Diluted shares outstanding (annual)

Insider trades

KIRA · In the last 12 months, insiders bought $0.0M and sold $2.2M of shares on the open market.

Open-market purchases and sales by officers, directors and 10% owners, from Form 4 filings. “Plan” marks trades under a pre-arranged Rule 10b5-1 plan.

In plain words: Insiders are the people who run or own a big part of the company. Buying with their own money can signal confidence; selling often has personal reasons, like taxes or diversifying.

Bought, 12 months

$0.0M

1 insider

Sold, 12 months

$2.2M

1 insider

Of sales under plans

0%

$0.0M

DateInsiderTradeSharesPriceValueFiling
Aug 8, 2026 Mani SharmaSee Remarks Bought 20 $160.57 $0.0M Form 4
May 20, 2026 Mani SharmaSee Remarks Sold 11,893 $185.78 $2.2M Form 4

Financial health

Can it carry its debts, and how well does it use its money?

Balance sheet

KIRA · AstraZeneca owes $22.1B more than it holds in cash.

Cash, debt and the ratios that show how comfortably AstraZeneca can carry it.

In plain words: What the company owns and what it owes. More cash than debt is a cushion for bad times; a lot of debt leaves less room when business slows down.

Cash vs debt (incl. leases)

Cash Debt
Fiscal year endFY21FY22FY23FY24FY25
Cash and short-term investments $6.4B$6.4B$6.0B$5.7B$5.7B
Debt incl. finance leases $29.8B$28.3B$27.5B$28.8B$27.8B
Debt / equity 0.8x0.8x0.7x0.7x0.6x
Interest coverage 0.8x2.8x5.0x5.7x8.1x
Current ratio 1.2x0.9x0.8x0.9x0.9x
Quick ratio 0.8x0.7x0.6x0.7x0.7x
Total assets $105.4B$96.5B$101.1B$104.0B$114.1B
Total liabilities $66.1B$59.4B$62.0B$63.2B$65.4B
Shareholders' equity $39.3B$37.0B$39.1B$40.8B$48.7B
Net debt (− = net cash) $23.4B$21.9B$21.5B$23.2B$22.1B

Returns on capital

KIRA · Its return on capital was 16.8%: every 100 invested in the business earned about 17 in a year.

After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.

In plain words: How much profit the business makes on the money put into it. A higher percentage means each dollar invested works harder.

Return on capital, equity and assets (annual)

Return on capital Return on equity Return on assets

Piotroski F-score

KIRA · AstraZeneca passes 9 of 9 financial health tests (Piotroski F-score).

Nine pass/fail tests of profitability, funding and efficiency. 8–9 is strong, 0–2 weak.

In plain words: Nine yes/no tests of financial health, one point each. A green tick is a pass: 7 to 9 points is solid, 0 to 3 is weak.

TestFY23FY24FY25
Net income is positive ✓ ✓ ✓
Cash from operations is positive ✓ ✓ ✓
Return on assets rose ✓ ✓ ✓
Cash from operations exceeds net income ✓ ✓ ✓
Debt fell relative to assets ✓ ✕ ✓
Current ratio rose ✕ ✓ ✓
Share count didn't rise ✕ ✕ ✓
Gross margin rose ✓ ✕ ✓
Revenue rose relative to assets ✓ ✓ ✓
F-score 7 / 96 / 99 / 9
Accruals ratio −4.4%−4.7%−4.0%
Altman Z'' 0.901.301.80

Price and value

What does the share cost, and how does it compare?

Similar companies

KIRA · AstraZeneca grew sales faster than 3 of its 4 similar companies.

Each company’s latest fiscal year. Fiscal years end in different months, so periods don’t line up exactly.

In plain words: The same numbers for similar companies, so you can tell whether a figure is high or low for this kind of business.

CompanyMarket capGrowthOp. marginFCF marginROICP/EF-score
AstraZeneca AZN $268.8B 8.6% 23.4% 20.0% 16.8% — 9
Pfizer PFE $169.8B −1.7% — 14.5% 7.3% 39.2x 6 Compare →
Merck MRK $347.3B 1.3% — 19.0% 24.8% 111.6x 4 Compare →
Eli Lilly LLY $1.14T 44.7% — 13.8% 40.8% 42.9x 8 Compare →
Bristol Myers Squibb BMY $126.2B −0.2% — 26.7% 15.2% 13.6x 8 Compare →

All figures

Every number, year by year.

10 years of figures

Amounts in USD. Hover a ratio’s name for its definition.

In plain words: Every number we have, year by year. Download it as a spreadsheet if you want to dig deeper.

Download CSV
Fiscal yearFY16FY17FY18FY19FY20FY21FY22FY23FY24FY25
Income statement
Revenue $23.0B $22.5B $22.1B $24.4B $26.6B $37.4B $44.4B $45.8B $54.1B $58.7B
Gross profit $18.9B $18.1B $17.2B $19.5B $21.3B $25.0B $32.0B $37.5B $43.9B $48.1B
Research and development $5.9B $5.8B $5.9B $6.1B $6.0B $9.7B $9.8B $10.9B $13.6B $14.2B
Operating income $4.9B $3.7B $3.4B $2.9B $5.2B $1.1B $3.8B $8.2B $10.0B $13.7B
Interest expense $1.4B $1.5B $1.4B $1.4B $1.3B $1.3B $1.3B $1.6B $1.7B $1.7B
Pretax income $3.6B $2.2B $2.0B $1.5B $3.9B −$265M $2.5B $6.9B $8.7B $12.4B
Income tax $146M −$641M −$57.0M $321M $772M −$380M −$792M $938M $1.7B $2.2B
Net income $3.5B $3.0B $2.2B $1.3B $3.2B $112M $3.3B $6.0B $7.0B $10.2B
Diluted EPS $2.76 $2.37 $1.70 $1.03 $2.44 $0.08 $2.11 $3.81 $4.50 $6.54
Diluted shares 1.27B 1.27B 1.27B 1.30B 1.31B 1.43B 1.56B 1.56B 1.56B 1.56B
Cash flow
Cash from operations $4.1B $3.6B $2.6B $3.0B $4.8B $6.0B $9.8B $10.3B $11.9B $14.6B
Capital expenditure $1.4B $1.3B $1.0B $979M $961M $1.1B $1.1B $1.4B $1.9B $2.8B
Free cash flow $2.7B $2.3B $1.6B $2.0B $3.8B $4.9B $8.7B $9.0B $9.9B $11.8B
Stock-based compensation $241M $220M $219M $259M $277M $615M $619M $579M $660M $719M
Acquisitions $2.6B $1.5B $0.0M $0.0M $0.0M $0.0M $0.0M $0.0M $0.0M $0.0M
Share buybacks $0.0M $0.0M $0.0M $0.0M $0.0M $149M $0.0M $0.0M $81.0M $521M
Dividends paid $3.6B $3.5B $3.5B $3.6B $3.6B $3.9B $4.4B $4.5B $4.6B $5.0B
Dividends and buybacks $3.6B $3.5B $3.5B $3.6B $3.6B $4.0B $4.4B $4.5B $4.7B $5.5B
Balance sheet
Cash and short-term investments $5.9B $4.6B $5.7B $6.2B $8.0B $6.4B $6.4B $6.0B $5.7B $5.7B
Total debt $16.8B $17.8B $19.1B $17.6B $19.7B $29.8B $28.3B $27.5B $28.8B $27.8B
Finance lease liabilities $0.0M $0.0M $0.0M $0.0M $0.0M $0.0M $0.0M $0.0M $0.0M $0.0M
Current assets $13.3B $13.2B $15.6B $15.6B $19.5B $26.2B $22.6B $25.1B $25.8B $28.7B
Current liabilities $15.3B $16.4B $16.3B $18.1B $20.3B $22.6B $26.3B $30.5B $27.9B $30.6B
Inventory $2.3B $3.0B $2.9B $3.2B $4.0B $9.0B $4.7B $5.4B $5.3B $6.6B
Property and equipment, net $6.8B $7.6B $7.4B $7.7B $8.3B $9.2B $8.5B $9.4B $10.3B $13.0B
Total assets $62.5B $63.4B $60.7B $61.4B $66.7B $105.4B $96.5B $101.1B $104.0B $114.1B
Total liabilities $45.9B $46.7B $46.6B $46.8B $51.1B $66.1B $59.4B $62.0B $63.2B $65.4B
Shareholders' equity $14.9B $15.0B $12.5B $13.1B $15.6B $39.3B $37.0B $39.1B $40.8B $48.7B
Margins
Gross margin 82.1% 80.8% 77.7% 79.8% 80.1% 66.8% 72.1% 82.0% 81.1% 81.9%
Operating margin 21.3% 16.4% 15.3% 12.0% 19.4% 2.8% 8.5% 17.9% 18.5% 23.4%
Net margin 15.2% 13.4% 9.8% 5.5% 12.0% 0.3% 7.4% 13.0% 13.0% 17.4%
FCF margin 11.7% 10.0% 7.1% 8.2% 14.4% 13.0% 19.7% 19.6% 18.4% 20.0%
Returns
Return on capital 17.3% 12.8% 11.8% 8.7% 15.6% 1.9% 6.2% 11.8% 13.0% 16.8%
Return on capital employed 10.6% 7.8% 7.4% 6.7% 11.5% 1.6% 4.9% 11.6% 13.6% 17.2%
Return on equity 21.0% 20.1% 15.7% 10.4% 22.2% 0.4% 8.6% 15.6% 17.6% 22.9%
Return on assets 5.7% 4.8% 3.5% 2.2% 5.0% 0.1% 3.3% 6.0% 6.9% 9.4%
Growth
Revenue growth −6.9% −2.3% −1.7% 10.4% 9.2% 40.6% 18.5% 3.3% 18.0% 8.6%
Net income growth 23.9% −14.2% −28.2% −38.1% 139.4% −96.5% 2,835.7% 81.1% 18.1% 45.3%
EPS growth 23.8% −14.1% −28.3% −39.4% 136.9% −96.7% 2,537.5% 80.6% 18.1% 45.3%
FCF growth 35.2% −16.6% −30.1% 26.4% 92.9% 26.9% 78.9% 3.1% 10.6% 18.4%
Share count change 0.1% 0.1% 0.0% 2.7% 0.9% 8.7% 9.3% 0.1% 0.1% −0.1%
Financial health
Debt / equity 1.1x 1.2x 1.5x 1.3x 1.3x 0.8x 0.8x 0.7x 0.7x 0.6x
Interest coverage 3.5x 2.4x 2.4x 2.0x 4.0x 0.8x 2.8x 5.0x 5.7x 8.1x
Current ratio 0.9x 0.8x 1.0x 0.9x 1.0x 1.2x 0.9x 0.8x 0.9x 0.9x
Quick ratio 0.7x 0.6x 0.8x 0.7x 0.8x 0.8x 0.7x 0.6x 0.7x 0.7x
Capital allocation
Capex / revenue 6.3% 5.9% 4.7% 4.0% 3.6% 2.9% 2.5% 3.0% 3.6% 4.8%
Stock comp / revenue 1.1% 1.0% 1.0% 1.1% 1.0% 1.6% 1.4% 1.3% 1.2% 1.2%
Payouts / FCF 131.9% 156.3% 221.2% 180.5% 93.1% 82.2% 50.1% 49.9% 47.4% 46.7%
Quality scores
Piotroski F-score — 3.0 5.0 6.0 7.0 5.0 6.0 7.0 6.0 9.0
Altman Z'' 1.1 0.9 0.9 0.5 1.0 1.0 0.7 0.9 1.3 1.8
Accruals ratio −1.1% −0.9% −0.8% −2.7% −2.5% −6.8% −6.5% −4.4% −4.7% −4.0%

Source: SEC EDGAR XBRL filings (CIK 0000901832). Data updated October 23, 2026. Quarterly fourth quarters are the full year minus the first nine months. For information only — not investment advice. Check the original filings before relying on any figure.

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