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Sarepta Therapeutics, Inc.

SRPT Nasdaq Pharmaceutical Preparations Financials FY2016–FY2025

Sarepta Therapeutics, Inc. had $2.2B of revenue in fiscal 2025, up 15.6% on the year before. Over five years, revenue changed +32.4% a year on average.

Download report 3-page PDF: the company, its results and charts with peers.

Last close Β· Oct 23, 2026

$17.73

2.5%

What Sarepta Therapeutics, Inc. does

SRPT Β· Pharmaceutical Preparations

From its latest annual report

No business description yet.

Filing details

Legal name
Sarepta Therapeutics, Inc.
Fiscal year ends
December 31, 2025
Latest annual report
10-K Β· Mar 2, 2026
Accession Β· CIK
0001193125-26-084144 Β· 0000873303

KIRA’s summary AI analyst

Hi! I read Sarepta Therapeutics, Inc.’s latest annual report (fiscal 2025). Here is what stands out:

2 strengths 4 to watch

1.Sales and profit

See section β†’
  • Sarepta Therapeutics, Inc. had $2.2B of revenue in fiscal 2025, up 15.6% on the year before. Over five years, revenue changed +32.4% a year on average.
  • Its operating margin was βˆ’31.8%, down 43.3Β pts: of every 100 in sales, about βˆ’32 is left after running the business.
  • Sarepta Therapeutics, Inc. lost $713M in fiscal 2025.

2.Cash and shareholders

See section β†’
  • Free cash flow was βˆ’$307M in fiscal 2025, βˆ’14.0% of revenue.
  • Sarepta Therapeutics, Inc. returned $25.0M to shareholders in fiscal 2025. The diluted share count fell 7.2%.
  • No open-market insider trades in the last 12 months.

3.Financial health

See section β†’
  • Sarepta Therapeutics, Inc. has $111M more cash than debt.
  • Its return on capital was βˆ’53.7%: every 100 invested in the business earned about βˆ’54 in a year.
  • Sarepta Therapeutics, Inc. passes 4 of 8 financial health tests (Piotroski F-score).

Sarepta Therapeutics, Inc. in 30 seconds

Good So-so Weak

Good

Are sales growing?

+15.6%

Yes. Sales grew 15.6% last year.

Weak

Does it make a profit?

βˆ’32.5%

No. It lost money last year.

Weak

Does profit turn into cash?

βˆ’14.0%

No. It spent more cash than it brought in.

So-so

How healthy are the accounts?

4 / 8

Mixed. It passes 4 of 8 health tests.

For information

How is the share priced?

β€”

No P/E: it made no profit over the last four quarters.

Rules of thumb on reported numbers. A starting point, not a recommendation.

Key numbers, fiscal 2025

Market cap Last close times the latest diluted share count, so it is approximate.
$1.9B
Oct 23 close
P/E Last close divided by diluted earnings per share over the last four quarters.
β€”
On βˆ’$1.60 EPS (TTM)

Revenue

Total sales reported in the income statement.

KIRA Β· Sarepta Therapeutics, Inc. had $2.2B of revenue in fiscal 2025, up 15.6% on the year before. Over five years, revenue changed +32.4% a year on average.

See the full section β†’

Operating margin

Operating income as a share of revenue.

KIRA Β· Its operating margin was βˆ’31.8%, down 43.3Β pts: of every 100 in sales, about βˆ’32 is left after running the business.

See the full section β†’

Net income

Profit after all expenses, interest and tax.

KIRA Β· Sarepta Therapeutics, Inc. lost $713M in fiscal 2025.

See the full section β†’

Free cash flow

Cash from operations minus capital spending.

KIRA Β· Free cash flow was βˆ’$307M in fiscal 2025, βˆ’14.0% of revenue.

See the full section β†’

Return on capital

After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.

KIRA Β· Its return on capital was βˆ’53.7%: every 100 invested in the business earned about βˆ’54 in a year.

See the full section β†’

Sales and profit

Is it selling more, and how much does it keep?

Results dates

In plain words: Every quarter, companies publish how much they sold and earned. These are the days Sarepta Therapeutics, Inc. did it, and the next one. Share prices often move a lot on those days.

Next results

November 5, 2026

Thursday Β· in 10 days

Time
After the market closes
Covers
Period ended Sep 30, 2026
Expected EPS
$0.17
Source
Earnings calendar
See who else reports that week β†’
Date Results for Time Source
Aug 5, 2026 Q2 '26 After the market closes 8-K β†—
May 6, 2026 Q1 '26 After the market closes 8-K β†—
Jan 12, 2026 Q4 '25 During market hours 8-K β†—
Nov 3, 2025 Q3 '25 After the market closes 8-K β†—
Jul 14, 2025 Q2 '25 Time not announced 8-K β†—
May 6, 2025 Q1 '25 After the market closes 10-Q β†—
Jan 13, 2025 Q4 '24 During market hours 8-K β†—
Nov 6, 2024 Q3 '24 After the market closes 10-Q β†—

From SEC filings: the results press release (8-K) or, without one, the quarterly or annual report.

Revenue and margins

KIRA Β· Sarepta Therapeutics, Inc. had $2.2B of revenue in fiscal 2025, up 15.6% on the year before. Over five years, revenue changed +32.4% a year on average. Its operating margin was βˆ’31.8%, down 43.3Β pts: of every 100 in sales, about βˆ’32 is left after running the business.

In plain words: Revenue is all the money customers paid. The margins show how many cents of each dollar of sales are left over at each step: after making the product (gross), after running the business (operating) and after everything, tax included (net).

Revenue

Revenue

Margins, % of revenue

Gross Operating Net FCF

Margins, % of revenue

Gross Operating Net FCF

Net income and earnings per share

KIRA Β· Sarepta Therapeutics, Inc. lost $713M in fiscal 2025.

Loss periods are shown in red.

In plain words: Net income is the profit left after every cost and tax. Earnings per share (EPS) splits that profit across every share, so it shows what one share earned.

Net income

Net income

Diluted EPS

Diluted EPS

Cash and shareholders

How much cash comes in, and where does it go?

Cash flow

KIRA Β· Free cash flow was βˆ’$307M in fiscal 2025, βˆ’14.0% of revenue.

Cash from operations minus capital spending.

In plain words: Profit on paper is not the same as cash in the bank. Free cash flow is the cash left after paying to run and maintain the business: the money it can hand back to shareholders, save or invest.

Free cash flow

Free cash flow

Cash from operations vs capital spending

Cash from operations Capital spending

Cash from operations vs capital spending

Cash from operations Capital spending

Dividends, buybacks and share count

KIRA Β· Sarepta Therapeutics, Inc. returned $25.0M to shareholders in fiscal 2025. The diluted share count fell 7.2%.

In plain words: Companies hand cash back in two ways: dividends (cash paid to shareholders) and buybacks (buying back their own shares, so each remaining share owns a bigger slice).

Dividends and buybacks

Dividends Buybacks

Dividends and buybacks

Dividends Buybacks

Diluted shares outstanding (annual)

Insider trades

KIRA Β· No open-market insider trades in the last 12 months.

Open-market purchases and sales by officers, directors and 10% owners, from Form 4 filings. β€œPlan” marks trades under a pre-arranged Rule 10b5-1 plan.

In plain words: Insiders are the people who run or own a big part of the company. Buying with their own money can signal confidence; selling often has personal reasons, like taxes or diversifying.

Bought, 12 months

$0.0M

0 insiders

Sold, 12 months

$0.0M

0 insiders

Of sales under plans

β€”

$0.0M

No open-market insider trades in the last 12 months.

Financial health

Can it carry its debts, and how well does it use its money?

Balance sheet

KIRA Β· Sarepta Therapeutics, Inc. has $111M more cash than debt.

Cash, debt and the ratios that show how comfortably Sarepta Therapeutics, Inc. can carry it.

In plain words: What the company owns and what it owes. More cash than debt is a cushion for bad times; a lot of debt leaves less room when business slows down.

Cash vs debt (incl. leases)

Cash Debt
Fiscal year endFY21FY22FY23FY24FY25
Cash and short-term investments $2.1B$2.0B$1.7B$1.4B$940M
Debt incl. finance leases $564M$1.5B$1.2B$1.1B$829M
Net debt / EBITDA β€”β€”β€”βˆ’0.9xβ€”
Debt / equity 0.6x4.0x1.4x0.7x0.7x
Interest coverage βˆ’7.2xβ€”β€”β€”β€”
Current ratio 5.8x4.1x3.9x4.2x2.3x
Quick ratio 5.3x3.8x3.5x3.2x1.5x
Total assets $3.1B$3.1B$3.3B$4.0B$3.3B
Total liabilities $2.2B$2.7B$2.4B$2.4B$2.2B
Shareholders' equity $928M$385M$859M$1.5B$1.1B
Net debt (βˆ’ = net cash) βˆ’$1.6Bβˆ’$445Mβˆ’$438Mβˆ’$218Mβˆ’$111M

Returns on capital

KIRA Β· Its return on capital was βˆ’53.7%: every 100 invested in the business earned about βˆ’54 in a year.

After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.

In plain words: How much profit the business makes on the money put into it. A higher percentage means each dollar invested works harder.

Return on capital, equity and assets (annual)

Return on capital Return on equity Return on assets

Piotroski F-score

KIRA Β· Sarepta Therapeutics, Inc. passes 4 of 8 financial health tests (Piotroski F-score).

Nine pass/fail tests of profitability, funding and efficiency. 8–9 is strong, 0–2 weak.

In plain words: Nine yes/no tests of financial health, one point each. A green tick is a pass: 7 to 9 points is solid, 0 to 3 is weak.

TestFY16FY17FY18FY19FY20FY21FY22FY23FY24FY25
Net income is positive βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ“ βœ•
Cash from operations is positive βœ• βœ• βœ• βœ• βœ“ βœ• βœ• βœ• βœ• βœ•
Return on assets rose β€” βœ“ βœ• βœ• βœ“ βœ“ βœ• βœ“ βœ“ βœ•
Cash from operations exceeds net income βœ“ βœ• βœ• βœ“ βœ“ βœ• βœ“ βœ“ βœ• βœ“
Debt fell relative to assets β€” βœ• βœ“ β€” β€” β€” βœ• βœ“ βœ“ βœ“
Current ratio rose β€” βœ“ βœ• βœ• βœ“ βœ• βœ• βœ• βœ“ βœ•
Share count didn't rise β€” βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ• βœ“
Gross margin rose β€” β€” β€” β€” β€” β€” β€” β€” β€” β€”
Revenue rose relative to assets β€” βœ“ βœ“ βœ“ βœ• βœ“ βœ“ βœ“ βœ“ βœ“
F-score β€” / 33 / 82 / 82 / 74 / 72 / 72 / 84 / 85 / 84 / 8
Accruals ratio βˆ’5.1%20.9%1.8%βˆ’14.9%βˆ’27.5%0.8%βˆ’12.0%βˆ’1.1%12.2%βˆ’13.9%
Altman Z'' βˆ’4.543.402.24βˆ’1.520.530.62βˆ’1.01βˆ’0.751.44βˆ’2.78

All figures

Every number, year by year.

10 years of figures

Amounts in USD. Hover a ratio’s name for its definition.

In plain words: Every number we have, year by year. Download it as a spreadsheet if you want to dig deeper.

Download CSV
Fiscal yearFY16FY17FY18FY19FY20FY21FY22FY23FY24FY25
Income statement
Revenue $5.4M $155M $301M $381M $540M $702M $933M $1.2B $1.9B $2.2B
Gross profit $5.3M β€” β€” β€” β€” β€” β€” β€” β€” $2.2B
Research and development $188M $167M $402M $561M $722M $771M $877M $877M $805M $1.5B
Operating income βˆ’$267M βˆ’$172M βˆ’$344M βˆ’$706M βˆ’$564M βˆ’$460M βˆ’$536M βˆ’$268M $218M βˆ’$700M
Interest expense $1.9M $5.8M $33.7M $30.7M $59.9M $63.5M βˆ’$53.2M βˆ’$22.0M βˆ’$18.4M βˆ’$38.1M
Pretax income βˆ’$267M βˆ’$48.6M βˆ’$363M βˆ’$714M βˆ’$553M βˆ’$419M βˆ’$690M βˆ’$520M $261M βˆ’$702M
Income tax β€” $2.1M βˆ’$0.7M $1.2M $1.1M βˆ’$0.2M $13.5M $15.9M $25.5M $11.2M
Net income βˆ’$267M βˆ’$50.7M βˆ’$362M βˆ’$715M βˆ’$554M βˆ’$419M βˆ’$703M βˆ’$536M $235M βˆ’$713M
Net income to common β€” β€” β€” β€” β€” β€” β€” βˆ’$536M $235M βˆ’$713M
Diluted EPS βˆ’$5.49 βˆ’$0.86 βˆ’$5.46 βˆ’$9.71 βˆ’$7.11 βˆ’$5.15 βˆ’$8.03 βˆ’$5.80 $2.34 βˆ’$7.13
Diluted shares 0.05B 0.06B 0.07B 0.07B 0.08B 0.08B 0.09B 0.09B 0.11B 0.10B
Cash flow
Cash from operations βˆ’$246M βˆ’$232M βˆ’$389M βˆ’$456M $107M βˆ’$443M βˆ’$325M βˆ’$501M βˆ’$206M βˆ’$205M
Capital expenditure $5.3M $12.0M $61.2M $59.6M $82.2M $38.5M $30.8M $76.1M $137M $102M
Free cash flow βˆ’$251M βˆ’$244M βˆ’$450M βˆ’$516M $25.3M βˆ’$482M βˆ’$356M βˆ’$577M βˆ’$343M βˆ’$307M
Depreciation and amortization $5.6M $8.1M $12.2M $24.5M $26.9M $38.0M $41.9M $44.4M $37.7M $44.5M
Stock-based compensation $30.0M $30.5M $50.1M $78.6M $108M $114M $233M $183M $184M $123M
Acquisitions β€” β€” β€” $173M β€” β€” β€” β€” β€” β€”
Share buybacks β€” β€” β€” β€” β€” β€” β€” $0.0M $0.0M $25.0M
Dividends and buybacks β€” β€” β€” β€” β€” β€” β€” $0.0M $0.0M $25.0M
Balance sheet
Cash and short-term investments $318M $1.1B $1.2B $1.1B $1.9B $2.1B $2.0B $1.7B $1.4B $940M
Total debt $17.7M $431M $421M β€” β€” $564M $1.5B $1.2B $1.1B $829M
Current assets $373M $1.2B $1.4B $1.5B $2.5B $2.6B $2.6B $2.6B $3.1B $2.5B
Current liabilities $75.4M $88.3M $174M $265M $416M $453M $620M $654M $732M $1.1B
Inventory $12.8M $83.6M $125M $171M $232M $186M $204M $323M $750M $915M
Property and equipment, net $37.8M $43.2M $97.0M $130M $190M $191M $180M $227M $340M $345M
Intangible assets $8.1M $14.4M $11.6M $12.5M $13.6M $14.2M $7.6M $29.6M $26.9M $28.9M
Total assets $424M $1.3B $1.6B $1.8B $3.0B $3.1B $3.1B $3.3B $4.0B $3.3B
Total liabilities $87.4M $519M $610M $1.0B $2.2B $2.2B $2.7B $2.4B $2.4B $2.2B
Preferred stock β€” β€” β€” β€” β€” $0.0M $0.0M $0.0M $0.0M $0.0M
Shareholders' equity $337M $789M $1.0B $818M $762M $928M $385M $859M $1.5B $1.1B
Margins
Gross margin 97.6% β€” β€” β€” β€” β€” β€” β€” β€” 98.8%
Operating margin βˆ’4,920.3% βˆ’111.0% βˆ’114.1% βˆ’185.3% βˆ’104.5% βˆ’65.5% βˆ’57.5% βˆ’21.5% 11.5% βˆ’31.8%
EBITDA margin βˆ’4,816.8% βˆ’105.8% βˆ’110.1% βˆ’178.8% βˆ’99.5% βˆ’60.1% βˆ’53.0% βˆ’18.0% 13.4% βˆ’29.8%
Net margin βˆ’4,930.2% βˆ’32.8% βˆ’120.2% βˆ’187.8% βˆ’102.6% βˆ’59.7% βˆ’75.4% βˆ’43.1% 12.4% βˆ’32.5%
FCF margin βˆ’4,633.1% βˆ’157.8% βˆ’149.4% βˆ’135.5% 4.7% βˆ’68.6% βˆ’38.2% βˆ’46.4% βˆ’18.0% βˆ’14.0%
Returns
Return on capital βˆ’577.1% βˆ’96.0% βˆ’97.3% β€” β€” β€” β€” βˆ’50.2% 15.0% βˆ’53.7%
Return on capital employed βˆ’76.5% βˆ’14.1% βˆ’23.4% βˆ’45.3% βˆ’22.0% βˆ’17.1% βˆ’21.4% βˆ’10.3% 6.7% βˆ’31.0%
Return on equity βˆ’79.4% βˆ’9.0% βˆ’39.7% βˆ’77.3% βˆ’70.1% βˆ’49.6% βˆ’107.2% βˆ’86.2% 19.7% βˆ’53.5%
Return on assets βˆ’63.0% βˆ’5.9% βˆ’24.5% βˆ’41.3% βˆ’23.1% βˆ’13.7% βˆ’22.4% βˆ’16.8% 6.5% βˆ’19.5%
Return on tangible equity βˆ’81.3% βˆ’6.5% βˆ’35.5% βˆ’88.8% βˆ’74.1% βˆ’45.8% βˆ’186.4% βˆ’64.6% 15.7% βˆ’64.2%
Growth
Revenue growth β€” 2,751.6% 94.7% 26.5% 41.8% 30.0% 32.9% 33.3% 53.0% 15.6%
Net income growth β€” β€” β€” β€” β€” β€” β€” β€” β€” βˆ’403.3%
EPS growth β€” β€” β€” β€” β€” β€” β€” β€” β€” βˆ’404.7%
FCF growth β€” β€” β€” β€” β€” βˆ’2,006.5% β€” β€” β€” β€”
Share count change β€” 20.8% 12.6% 11.1% 5.9% 4.2% 7.7% 5.5% 16.8% βˆ’7.2%
Financial health
Net debt / EBITDA β€” β€” β€” β€” β€” β€” β€” β€” βˆ’0.9x β€”
Debt / equity 0.1x 0.5x 0.4x β€” β€” 0.6x 4.0x 1.4x 0.7x 0.7x
Interest coverage βˆ’141.0x βˆ’29.6x βˆ’10.2x βˆ’23.0x βˆ’9.4x βˆ’7.2x β€” β€” β€” β€”
Current ratio 5.0x 13.9x 8.2x 5.5x 6.0x 5.8x 4.1x 3.9x 4.2x 2.3x
Quick ratio 4.8x 13.0x 7.5x 4.9x 5.4x 5.3x 3.8x 3.5x 3.2x 1.5x
Capital allocation
Capex / revenue 98.5% 7.8% 20.3% 15.7% 15.2% 5.5% 3.3% 6.1% 7.2% 4.6%
Stock comp / revenue 552.7% 19.7% 16.7% 20.6% 20.0% 16.2% 25.0% 14.7% 9.7% 5.6%
Quality scores
Piotroski F-score β€” 3.0 2.0 2.0 4.0 2.0 2.0 4.0 5.0 4.0
Altman Z'' βˆ’4.5 3.4 2.2 βˆ’1.5 0.5 0.6 βˆ’1.0 βˆ’0.7 1.4 βˆ’2.8
Accruals ratio βˆ’5.1% 20.9% 1.8% βˆ’14.9% βˆ’27.5% 0.8% βˆ’12.0% βˆ’1.1% 12.2% βˆ’13.9%

Source: SEC EDGAR XBRL filings (CIK 0000873303). Data updated October 24, 2026. Quarterly fourth quarters are the full year minus the first nine months. For information only β€” not investment advice. Check the original filings before relying on any figure.

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