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Ascendis Pharma A/S

ASND Nasdaq Pharmaceutical Preparations Financials FY2016–FY2025

Ascendis Pharma A/S had $812M of revenue in fiscal 2025, up 106.4% on the year before. Over five years, revenue changed +152.4% a year on average.

Today
—
Previous close
—
Market cap
$15.2B
P/E
—
52-week range
$196.01 $277.18

Last close · Oct 30, 2026

$251.27

+$47.56 (+23.35%) past year

Share price

Ascendis Pharma A/S

What Ascendis Pharma A/S does

ASND · Pharmaceutical Preparations

From its latest annual report

No business description yet.

Filing details

Legal name
Ascendis Pharma A/S
Fiscal year ends
December 31, 2025
Latest annual report
20-F · Feb 11, 2026
Accession · CIK
0001193125-26-046590 · 0001612042

Earnings calendar · Ascendis Pharma A/S

Every quarter, companies publish how much they sold and earned. These are the days Ascendis Pharma A/S did it, and the next one. Share prices often move a lot on those days.

Next results

November 11, 2026

Wednesday · in 10 days

Time
Time not announced
Covers
Period ended Sep 30, 2026
Expected EPS
$1.13
Source
Earnings calendar
See who else reports that week →
Date Results for Time Source
Feb 11, 2026 Q4 '25 After the market closes 20-F ↗
Feb 12, 2025 Q4 '24 After the market closes 20-F ↗
Feb 7, 2024 Q4 '23 After the market closes 20-F ↗
Feb 16, 2023 Period ended Dec 31, 2022 After the market closes 20-F ↗
Mar 2, 2022 Period ended Dec 31, 2021 After the market closes 20-F ↗
Mar 10, 2021 Period ended Dec 31, 2020 After the market closes 20-F ↗
Apr 3, 2020 Period ended Dec 31, 2019 Time not announced 20-F ↗
Apr 3, 2019 Period ended Dec 31, 2018 After the market closes 20-F ↗

From SEC filings: the results press release (8-K) or, without one, the quarterly or annual report.

KIRA’s summary AI analyst

Hi! I read Ascendis Pharma A/S’s latest annual report (fiscal 2025). Here is what stands out:

1 strength 2 to watch

1.Sales and profit

See section →
  • Ascendis Pharma A/S had $812M of revenue in fiscal 2025, up 106.4% on the year before. Over five years, revenue changed +152.4% a year on average.
  • Its operating margin was −18.9%, up 57.7 pts: of every 100 in sales, about −19 is left after running the business.
  • Ascendis Pharma A/S lost $257M in fiscal 2025.

2.Cash and shareholders

See section →
  • Ascendis Pharma A/S returned $19.6M to shareholders in fiscal 2025. The diluted share count rose 4.7%.
  • In the last 12 months, insiders bought $0.8M and sold $5.5M of shares on the open market.

Ascendis Pharma A/S in 30 seconds

Good So-so Weak

Good

Are sales growing?

+106.4%

Yes. Sales grew 106.4% last year.

Weak

Does it make a profit?

−31.7%

No. It lost money last year.

Weak

Is debt under control?

$122M

Risky. It owes more than it holds in cash and has no operating profit to repay it.

So-so

How healthy are the accounts?

5 / 9

Mixed. It passes 5 of 9 health tests.

For information

How is the share priced?

—

No P/E: it made no profit over the last four quarters.

Rules of thumb on reported numbers. A starting point, not a recommendation.

Key numbers, fiscal 2025

Market cap Last close times the latest diluted share count, so it is approximate.
$15.2B
Oct 30 close
P/E Last close divided by diluted earnings per share over the last four quarters.
—
On −$4.24 EPS (TTM)

Revenue

Total sales reported in the income statement.

KIRA · Ascendis Pharma A/S had $812M of revenue in fiscal 2025, up 106.4% on the year before. Over five years, revenue changed +152.4% a year on average.

See the full section →

Operating margin

Operating income as a share of revenue.

KIRA · Its operating margin was −18.9%, up 57.7 pts: of every 100 in sales, about −19 is left after running the business.

See the full section →

Net income

Profit after all expenses, interest and tax.

KIRA · Ascendis Pharma A/S lost $257M in fiscal 2025.

See the full section →

Free cash flow

Cash from operations minus capital spending.

Return on capital

After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.

Sales and profit

Is it selling more, and how much does it keep?

Revenue and margins

KIRA summarises the numbers

  • Ascendis Pharma A/S had $812M of revenue in fiscal 2025, up 106.4% on the year before.

    Over five years, revenue changed +152.4% a year on average.

  • Its operating margin was −18.9%, up 57.7 pts: of every 100 in sales, about −19 is left after running the business.

Revenue

Revenue

Margins, % of revenue

Gross Operating Net FCF

Margins, % of revenue

Gross Operating Net FCF

In plain words: Revenue is all the money customers paid. The margins show how many cents of each dollar of sales are left over at each step: after making the product (gross), after running the business (operating) and after everything, tax included (net).

Net income and earnings per share

Loss periods are shown in red.

KIRA summarises the numbers

  • Ascendis Pharma A/S lost $257M in fiscal 2025.

Net income

Net income

Diluted EPS

Diluted EPS

In plain words: Net income is the profit left after every cost and tax. Earnings per share (EPS) splits that profit across every share, so it shows what one share earned.

Cash and shareholders

How much cash comes in, and where does it go?

Cash flow

Cash from operations minus capital spending.

Free cash flow

Free cash flow

Cash from operations vs capital spending

Cash from operations Capital spending

Cash from operations vs capital spending

Cash from operations Capital spending

In plain words: Profit on paper is not the same as cash in the bank. Free cash flow is the cash left after paying to run and maintain the business: the money it can hand back to shareholders, save or invest.

Dividends, buybacks and share count

KIRA summarises the numbers

  • Ascendis Pharma A/S returned $19.6M to shareholders in fiscal 2025.

    The diluted share count rose 4.7%.

Dividends and buybacks

Dividends Buybacks

Dividends and buybacks

Dividends Buybacks

Diluted shares outstanding (annual)

In plain words: Companies hand cash back in two ways: dividends (cash paid to shareholders) and buybacks (buying back their own shares, so each remaining share owns a bigger slice).

Insider trades

Open-market purchases and sales by officers, directors and 10% owners, from Form 4 filings. “Plan” marks trades under a pre-arranged Rule 10b5-1 plan.

KIRA summarises the numbers

  • In the last 12 months, insiders bought $0.8M and sold $5.5M of shares on the open market.

Bought, 12 months

$0.8M

2 insiders

Sold, 12 months

$5.5M

3 insiders

Of sales under plans

0%

$0.0M

DateInsiderTradeSharesPriceValueFiling
Sep 8, 2026 Mads BodenhoffSVP & Pao Sold 3,000 $270.19 $0.8M Form 4
Sep 2, 2026 Lars HoltugDirector Sold 236 $264.13 $0.1M Form 4
Aug 14, 2026 Jean Jacques BienaimeDirector Bought 2,000 $246.33 $0.5M Form 4
Jun 2, 2026 Scott Thomas SmithEVP & Chief Financial Officer Bought 100 $219.00 $0.0M Form 4
May 29, 2026 Jean Jacques BienaimeDirector Bought 500 $223.12 $0.1M Form 4
May 29, 2026 Scott Thomas SmithEVP & Chief Financial Officer Bought 250 $223.32 $0.1M Form 4
May 26, 2026 Jean Jacques BienaimeDirector Bought 400 $237.81 $0.1M Form 4
May 11, 2026 Flemming Steen JensenSee Remarks Sold 19,460 $238.49 $4.6M Form 4

In plain words: Insiders are the people who run or own a big part of the company. Buying with their own money can signal confidence; selling often has personal reasons, like taxes or diversifying.

Financial health

Can it carry its debts, and how well does it use its money?

Balance sheet

Cash, debt and the ratios that show how comfortably Ascendis Pharma A/S can carry it.

KIRA summarises the numbers

  • Ascendis Pharma A/S owes $122M more than it holds in cash.

Cash vs debt (incl. leases)

Cash Debt
Fiscal year endFY21FY22FY23FY24FY25
Cash and short-term investments $505M$474M$433M$581M$724M
Debt incl. finance leases $119M$426M$603M$793M$846M
Debt / equity 0.1x1.5x———
Interest coverage −115.5x−18.3x−10.3x−4.3x−1.7x
Current ratio 8.0x5.4x1.0x1.2x1.0x
Quick ratio 7.3x4.6x0.7x0.8x0.8x
Total assets $1.2B$1.2B$912M$1.2B$1.5B
Total liabilities $228M$881M$1.1B$1.3B$1.7B
Shareholders' equity $1.0B$281M−$161M−$110M−$191M
Net debt (− = net cash) −$387M−$48.6M$169M$212M$122M

In plain words: What the company owns and what it owes. More cash than debt is a cushion for bad times; a lot of debt leaves less room when business slows down.

Returns on capital

After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.

Return on capital, equity and assets (annual)

Return on capital Return on equity Return on assets

In plain words: How much profit the business makes on the money put into it. A higher percentage means each dollar invested works harder.

Piotroski F-score

Nine pass/fail tests of profitability, funding and efficiency. 8–9 is strong, 0–2 weak.

KIRA summarises the numbers

  • Ascendis Pharma A/S passes 5 of 9 financial health tests (Piotroski F-score).

TestFY21FY22FY23FY24FY25
F-score 2 / 83 / 93 / 96 / 95 / 9
Accruals ratio 3.3%−7.7%−1.5%−7.3%−23.1%
Altman Z'' —————
Net income is positive ✕ ✕ ✕ ✕ ✕
Cash from operations is positive ✕ ✕ ✕ ✕ ✓
Return on assets rose ✓ ✕ ✕ ✓ ✓
Cash from operations exceeds net income ✕ ✓ ✓ ✓ ✓
Debt fell relative to assets — ✕ ✕ ✓ ✓
Current ratio rose ✕ ✕ ✕ ✓ ✕
Share count didn't rise ✕ ✕ ✕ ✕ ✕
Gross margin rose ✕ ✓ ✓ ✓ ✕
Revenue rose relative to assets ✓ ✓ ✓ ✓ ✓

In plain words: Nine yes/no tests of financial health, one point each. A green tick is a pass: 7 to 9 points is solid, 0 to 3 is weak.

All figures

Every number, year by year.

10 years of figures

Amounts in USD. Hover a ratio’s name for its definition.

Download CSV
See the figures for 10 years
Fiscal yearFY16FY17FY18FY19FY20FY21FY22FY23FY24FY25
Income statement
Revenue $5.1M $1.7M $12.5M $15.0M $7.9M $9.2M $53.8M $288M $393M $812M
Gross profit — — — $15.0M $7.9M $5.0M $41.0M $240M $346M $705M
Research and development $73.0M $112M $166M $214M $297M $350M $399M $447M $332M $342M
Operating income −$80.6M −$126M −$183M −$254M −$377M −$534M −$590M −$493M −$302M −$154M
Interest expense $0.0M $0.1M $0.1M $1.4M $2.2M $4.6M $32.2M $47.7M $70.9M $90.9M
Pretax income −$76.0M −$140M −$154M −$244M −$478M −$454M −$607M −$513M −$404M −$240M
Income tax −$0.3M −$0.5M −$0.5M −$0.3M −$0.2M −$0.4M $5.7M $7.9M $5.2M $17.3M
Net income −$75.8M −$140M −$154M −$244M −$478M −$454M −$613M −$521M −$409M −$257M
Net income to common — — −$154M −$244M −$478M −$454M −$613M −$521M −$409M −$257M
Diluted EPS −$2.85 −$4.15 −$3.74 −$5.25 −$9.44 −$8.28 −$10.93 −$9.25 −$7.06 −$4.24
Diluted shares 0.03B 0.03B 0.04B 0.05B 0.05B 0.05B 0.06B 0.06B 0.06B 0.06B
Cash flow
Cash from operations −$66.6M −$107M −$164M −$197M −$310M −$494M −$521M −$505M −$331M $60.8M
Capital expenditure $0.7M $1.1M $3.1M $5.8M $22.6M $28.0M $15.2M $2.6M — —
Free cash flow −$67.3M −$108M −$167M −$203M −$332M −$522M −$536M −$508M — —
Stock-based compensation $8.1M $10.9M $23.2M $42.0M $60.6M $79.0M $67.5M $72.1M $103M $131M
Share buybacks — — — — — $25.6M $111M $0.0M $0.0M $19.6M
Dividends and buybacks — — — — — $25.6M $111M $0.0M $0.0M $19.6M
Balance sheet
Cash and short-term investments $190M $234M $318M $672M $717M $505M $474M $433M $581M $724M
Total debt — — — — — $119M $426M $603M $793M $846M
Current assets $194M $245M $335M $687M $908M $913M $985M $777M $1.1B $1.3B
Current liabilities $14.2M $28.5M $44.6M $53.9M $64.8M $114M $183M $814M $943M $1.3B
Inventory — — — — $0.0M $85.4M $139M $231M $307M $354M
Property and equipment, net $2.5M $3.1M $5.0M $50.6M $133M $143M $138M $122M $103M $172M
Goodwill $3.7M $4.2M $4.0M $3.9M — — — — — —
Total assets $200M $253M $365M $760M $1.2B $1.2B $1.2B $912M $1.2B $1.5B
Total liabilities $14.2M $28.5M $44.6M $89.4M $173M $228M $881M $1.1B $1.3B $1.7B
Shareholders' equity $186M $225M $321M $671M $1.0B $1.0B $281M −$161M −$110M −$191M
Margins
Gross margin — — — 100.0% 100.0% 54.7% 76.3% 83.4% 87.8% 86.8%
Operating margin −1,583.1% −7,290.1% −1,462.6% −1,695.1% −4,755.0% −5,808.6% −1,097.9% −170.8% −76.7% −18.9%
Net margin −1,487.3% −8,097.6% −1,229.5% −1,630.0% −6,025.5% −4,931.6% −1,139.6% −180.5% −104.0% −31.7%
FCF margin −1,321.1% −6,276.9% −1,336.8% −1,354.0% −4,191.1% −5,674.4% −997.0% −176.1% — —
Returns
Return on capital — — — — — −68.7% −200.8% −4,627.4% −233.2% —
Return on capital employed −43.3% −56.0% −56.9% −35.9% −33.1% −47.9% −60.3% −500.5% −106.9% −56.1%
Return on equity −40.7% −68.0% −56.3% −49.2% −56.2% −44.7% −95.6% −868.5% — —
Return on assets −37.8% −61.6% −49.7% −43.4% −48.7% −37.3% −51.3% −50.2% −38.3% −18.7%
Return on tangible equity −41.5% −63.4% −48.5% −36.6% −46.4% −45.3% −218.2% — — —
Growth
Revenue growth — −66.1% 623.8% 19.9% −47.1% 16.1% 484.7% 436.3% 36.4% 106.4%
Share count change — 26.6% 22.2% 13.2% 8.8% 8.2% 2.4% 0.4% 2.9% 4.7%
Financial health
Debt / equity — — — — — 0.1x 1.5x — — —
Interest coverage −14,662.5x −1,149.4x −1,218.2x −185.7x −172.4x −115.5x −18.3x −10.3x −4.3x −1.7x
Current ratio 13.7x 8.6x 7.5x 12.7x 14.0x 8.0x 5.4x 1.0x 1.2x 1.0x
Quick ratio 13.7x 8.6x 7.5x 12.7x 14.0x 7.3x 4.6x 0.7x 0.8x 0.8x
Capital allocation
Capex / revenue 14.6% 61.5% 25.0% 38.6% 285.6% 304.8% 28.3% 0.9% — —
Stock comp / revenue 158.9% 634.6% 185.7% 280.3% 764.7% 859.2% 125.4% 25.0% 26.3% 16.1%
Quality scores
Piotroski F-score — 1.0 2.0 3.0 2.0 2.0 3.0 3.0 6.0 5.0
Accruals ratio −4.6% −14.3% 3.3% −8.4% −17.1% 3.3% −7.7% −1.5% −7.3% −23.1%

In plain words: Every number we have, year by year. Download it as a spreadsheet if you want to dig deeper.

Latest SEC filings

The original documents every number on this page comes from.

All filings on EDGAR →

Source: SEC EDGAR XBRL filings (CIK 0001612042). Data updated November 1, 2026. Quarterly fourth quarters are the full year minus the first nine months. Filed in EUR under IFRS and converted to US$: income and cash-flow lines at each period's average exchange rate, balance-sheet lines at the period-end rate. For information only — not investment advice. Check the original filings before relying on any figure.

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