Amgen
AMGN Nasdaq Biotechnology Financials FY2016–FY2025
Amgen's revenue rose 9.9% to $36.8 billion in fiscal 2025. Its operating margin was 24.7%, up from 21.7% a year earlier. Free cash flow was $8.1 billion, down 22.1%. It paid out $5.1 billion in dividends and buybacks, 63% of free cash flow. The diluted share count rose 0.2%.
What Amgen does
Amgen is a biotechnology company that discovers, develops, makes and sells medicines for serious diseases. It was incorporated in 1980 and has a presence in approximately 100 countries. It reports one operating segment, human therapeutics.
Its products include Repatha for cholesterol and cardiovascular risk, Uplizna for rare immune conditions, Imdelltra for small cell lung cancer, Tezspire for asthma and nasal polyps, which it markets with a partner, and Tepezza for thyroid eye disease. It is testing MariTide, a chronic weight management candidate, in Phase 3 studies. Its drugs go mainly through wholesalers: in the United States, substantially all of its sales are to pharmaceutical wholesale distributors. Three of them, McKesson, Cencora and Cardinal Health, each accounted for more than 10% of revenue and together for 77% of worldwide gross revenue in 2025.
The United States is its largest market, and it sells outside the U.S. through its own affiliates and through partners such as Astellas, BeOne, Takeda and Kyowa Kirin in Asia. It also promotes some products directly to patients through print, television and online media.
- Legal name
- Amgen Inc.
- Fiscal year ends
- December 31, 2025
- Latest annual report
- 10-K · Feb 13, 2026
- Accession · CIK
- 0000318154-26-000010
0000318154
Revenue and margins
Amgen had $36.8B of revenue in fiscal 2025, up 10.0% on the year before.
Net income and earnings per share
From fiscal 2016 to 2025, diluted EPS grew 3.7% a year. Loss periods are shown in red.
Returns on capital
After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.
Cash flow
Free cash flow was $8.1B in fiscal 2025, 22.0% of revenue. Cash from operations minus capital spending.
Dividends, buybacks and share count
Amgen returned $5.1B to shareholders in fiscal 2025, 63% of free cash flow. The diluted share count rose 0.2%.
Value Amgen yourself
Change the assumptions and see what they imply per share. These are models, not forecasts or price targets — the answer depends entirely on what you put in.
Discounted cash flow
Value per share
—
Adds net cash of −$45.5B and divides by 542.0M diluted shares. Ten years of cash flows plus a terminal value, discounted to today.
Earnings multiple
Value per share
—
Reference multiples: today 27.3x · peers 30.5x · sector 28.4x.
Balance sheet
Cash, debt and the ratios that show how comfortably Amgen can carry it.
| Fiscal year end | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|
| Cash and short-term investments | $8.0B | $9.3B | $10.9B | $12.0B | $9.1B |
| Debt incl. finance leases | $33.3B | $38.9B | $64.6B | $60.1B | $54.6B |
| Net debt / EBITDA | 2.3x | 2.3x | 4.5x | 3.8x | 3.2x |
| Debt / equity | 5.0x | 10.6x | 10.4x | 10.2x | 6.3x |
| Interest coverage | 6.4x | 6.8x | 2.8x | 2.3x | 3.3x |
| Current ratio | 1.6x | 1.4x | 1.7x | 1.3x | 1.1x |
| Quick ratio | 1.3x | 1.1x | 1.1x | 1.0x | 0.9x |
| Total assets | $61.2B | $65.1B | $97.2B | $91.8B | $90.6B |
| Total liabilities | $54.5B | $61.5B | $90.9B | $86.0B | $81.9B |
| Shareholders' equity | $6.7B | $3.7B | $6.2B | $5.9B | $8.7B |
| Net debt (− = net cash) | $25.3B | $29.6B | $53.7B | $48.1B | $45.5B |
Insider trades
Open-market purchases and sales by officers, directors and 10% owners, from Form 4 filings. 'Plan' marks trades under a pre-arranged Rule 10b5-1 plan.
Bought, 12 months
$0.0M
0 insiders
Sold, 12 months
$29.3M
6 insiders
Of sales under plans
0%
$0.0M
| Date | Insider | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| Aug 13, 2026 | Rachna KhoslaSVP, Business Development | Sold | 1,252 | $416.43 | $0.5M | Form 4 |
| Aug 11, 2026 | Rachna KhoslaSVP, Business Development | Sold | 2,000 | $412.57 | $0.8M | Form 4 |
| Aug 6, 2026 | Derek MillerSVP, Human Resources | Sold | 3,890 | $402.54 | $1.6M | Form 4 |
| Aug 6, 2026 | Nancy A. GrygielSVP & CCO | Sold | 2,970 | $402.16 | $1.2M | Form 4 |
| May 4, 2026 | Nancy A. GrygielSVP & CCO | Sold | 1,237 | $323.73 | $0.4M | Form 4 |
| Feb 26, 2026 | Esteban SantosEVP, Operations | Sold | 54,792 | $379.12 | $20.8M | Form 4 |
| Feb 19, 2026 | Matthew C. BuschVP, Finance & CAO | Sold | 1,000 | $375.79 | $0.4M | Form 4 |
| Nov 20, 2025 | Nancy A. GrygielSVP & CCO | Sold | 3,139 | $337.26 | $1.1M | Form 4 |
| Nov 12, 2025 | Murdo GordonEVP, Global Commercial Ops | Sold | 6,879 | $336.83 | $2.3M | Form 4 |
| Nov 12, 2025 | Rachna KhoslaSVP, Business Development | Sold | 890 | $336.24 | $0.3M | Form 4 |
Piotroski F-score
Nine pass/fail tests of profitability, funding and efficiency. 8–9 is strong, 0–2 weak.
| Test | FY23 | FY24 | FY25 |
|---|---|---|---|
| Net income is positive | ✓ | ✓ | ✓ |
| Cash from operations is positive | ✓ | ✓ | ✓ |
| Return on assets rose | ✕ | ✕ | ✓ |
| Cash from operations exceeds net income | ✓ | ✓ | ✓ |
| Debt fell relative to assets | ✕ | ✓ | ✓ |
| Current ratio rose | ✓ | ✕ | ✕ |
| Share count didn't rise | ✓ | ✕ | ✕ |
| Gross margin rose | ✕ | ✕ | ✓ |
| Revenue rose relative to assets | ✓ | ✕ | ✓ |
| F-score | 6 / 9 | 4 / 9 | 7 / 9 |
| Accruals ratio | −2.2% | −7.8% | −2.5% |
| Altman Z'' | 0.53 | 0.05 | 0.14 |
Similar companies
Each company's latest fiscal year. Fiscal years end in different months, so periods don't line up exactly.
| Company | Market cap | Growth | Op. margin | FCF margin | ROIC | P/E | F-score | |
|---|---|---|---|---|---|---|---|---|
| Amgen AMGN | $239.0B | 10.0% | 24.7% | 22.0% | 14.4% | 27.3x | 7 | |
| Gilead Sciences GILD | $194.0B | 2.4% | 34.0% | 32.1% | 23.0% | — | 8 | Compare → |
| AbbVie ABBV | $505.9B | 8.6% | 24.7% | 29.1% | 15.7% | 80.7x | 7 | Compare → |
| Regeneron Pharmaceuticals REGN | $85.3B | 1.0% | 25.0% | 28.5% | 12.7% | 19.9x | 5 | Compare → |
| Vertex Pharmaceuticals VRTX | $133.7B | 8.9% | 34.8% | 26.6% | 31.5% | 30.5x | 6 | Compare → |
10 years of figures
US$ millions unless stated. Hover a ratio's name for its definition.
| Fiscal year | FY16 | FY17 | FY18 | FY19 | FY20 | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|---|---|---|---|---|
| Income statement | ||||||||||
| Revenue | $23.0B | $22.8B | $23.7B | $23.4B | $25.4B | $26.0B | $26.3B | $28.2B | $33.4B | $36.8B |
| Gross profit | $18.8B | $18.8B | $19.6B | $19.0B | $19.3B | $19.5B | $19.9B | $19.7B | $20.6B | $24.7B |
| Research and development | $3.8B | $3.6B | $3.7B | $4.1B | $4.2B | $4.8B | $4.4B | $4.8B | $6.0B | $7.3B |
| Operating income | $9.8B | $10.0B | $10.3B | $9.7B | $9.1B | $7.6B | $9.6B | $7.9B | $7.3B | $9.1B |
| Interest expense | $1.3B | $1.3B | $1.4B | $1.3B | $1.3B | $1.2B | $1.4B | $2.9B | $3.2B | $2.8B |
| Pretax income | $9.2B | $9.6B | $9.5B | $9.1B | $8.1B | $6.7B | $7.3B | $7.9B | $4.6B | $9.0B |
| Income tax | $1.4B | $7.6B | $1.2B | $1.3B | $869M | $808M | $794M | $1.1B | $519M | $1.3B |
| Net income | $7.7B | $2.0B | $8.4B | $7.8B | $7.3B | $5.9B | $6.6B | $6.7B | $4.1B | $7.7B |
| Diluted EPS | $10.24 | $2.69 | $12.62 | $12.88 | $12.31 | $10.28 | $12.11 | $12.49 | $7.56 | $14.23 |
| Diluted shares | 0.75B | 0.74B | 0.67B | 0.61B | 0.59B | 0.57B | 0.54B | 0.54B | 0.54B | 0.54B |
| Cash flow | ||||||||||
| Cash from operations | $10.4B | $11.2B | $11.3B | $9.2B | $10.5B | $9.3B | $9.7B | $8.5B | $11.5B | $10.0B |
| Capital expenditure | $738M | $664M | $738M | $618M | $608M | $880M | $936M | $1.1B | $1.1B | $1.9B |
| Free cash flow | $9.6B | $10.5B | $10.6B | $8.5B | $9.9B | $8.4B | $8.8B | $7.4B | $10.4B | $8.1B |
| Depreciation and amortization | $2.1B | $2.0B | $1.9B | $2.2B | $3.6B | $3.4B | $3.4B | $4.1B | $5.6B | $5.2B |
| Stock-based compensation | $311M | $329M | $311M | $308M | $330M | $341M | $401M | $431M | $530M | $494M |
| Acquisitions | $0.0M | $19.0M | $195M | $13.6B | $0.0M | $2.5B | $3.8B | $27.0B | $0.0M | $53.0M |
| Share buybacks | $3.0B | $3.2B | $17.8B | $7.7B | $3.5B | $5.0B | $6.4B | $0.0M | $200M | $0.0M |
| Dividends paid | $3.0B | $3.4B | $3.5B | $3.5B | $3.8B | $4.0B | $4.2B | $4.6B | $4.8B | $5.1B |
| Dividends and buybacks | $6.0B | $6.5B | $21.3B | $11.2B | $7.2B | $9.0B | $10.6B | $4.6B | $5.0B | $5.1B |
| Balance sheet | ||||||||||
| Cash and short-term investments | $3.2B | $41.7B | $29.3B | $8.9B | $10.6B | $8.0B | $9.3B | $10.9B | $12.0B | $9.1B |
| Total debt | $34.6B | $35.3B | $33.9B | $29.9B | $33.0B | $33.3B | $38.9B | $64.6B | $60.1B | $54.6B |
| Finance lease liabilities | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M |
| Current assets | $46.0B | $49.5B | $37.6B | $18.4B | $21.1B | $19.4B | $22.2B | $30.3B | $29.0B | $29.1B |
| Current liabilities | $11.2B | $9.0B | $13.5B | $12.8B | $11.7B | $12.2B | $15.7B | $18.4B | $23.1B | $25.5B |
| Inventory | $2.7B | $2.8B | $2.9B | $3.6B | $3.9B | $4.1B | $4.9B | $9.5B | $7.0B | $6.2B |
| Property and equipment, net | $5.0B | $5.0B | $5.0B | $4.9B | $4.9B | $5.2B | $5.4B | $5.9B | $6.5B | $7.9B |
| Total assets | $77.6B | $80.0B | $66.4B | $59.7B | $62.9B | $61.2B | $65.1B | $97.2B | $91.8B | $90.6B |
| Total liabilities | $47.8B | $54.7B | $53.9B | $50.0B | $53.5B | $54.5B | $61.5B | $90.9B | $86.0B | $81.9B |
| Shareholders' equity | $29.9B | $25.2B | $12.5B | $9.7B | $9.4B | $6.7B | $3.7B | $6.2B | $5.9B | $8.7B |
| Margins | ||||||||||
| Gross margin | 81.9% | 82.2% | 82.7% | 81.4% | 75.8% | 75.2% | 75.7% | 70.0% | 61.5% | 67.3% |
| Operating margin | 42.6% | 43.7% | 43.2% | 41.4% | 36.0% | 29.4% | 36.3% | 28.0% | 21.7% | 24.7% |
| EBITDA margin | 51.8% | 52.2% | 51.4% | 50.9% | 50.1% | 42.5% | 49.3% | 42.5% | 38.5% | 38.8% |
| Net margin | 33.6% | 8.7% | 35.4% | 33.6% | 28.6% | 22.7% | 24.9% | 23.8% | 12.2% | 21.0% |
| FCF margin | 41.8% | 46.0% | 44.5% | 36.5% | 38.9% | 32.3% | 33.4% | 26.1% | 31.1% | 22.0% |
| Returns | ||||||||||
| Return on capital | 14.2% | 12.5% | 50.1% | 34.7% | 26.2% | 21.1% | 26.1% | 14.5% | 11.3% | 14.4% |
| Return on capital employed | 15.2% | 14.5% | 16.6% | 19.4% | 18.6% | 15.2% | 19.4% | 12.3% | 9.8% | 13.6% |
| Return on equity | 26.7% | 7.2% | 44.5% | 70.7% | 76.1% | 73.2% | 126.5% | 135.8% | 67.6% | 106.1% |
| Return on assets | 10.4% | 2.5% | 11.5% | 12.4% | 11.8% | 9.5% | 10.4% | 8.3% | 4.3% | 8.5% |
| Growth | ||||||||||
| Revenue growth | 6.1% | −0.6% | 3.9% | −1.6% | 8.8% | 2.2% | 1.3% | 7.1% | 18.6% | 10.0% |
| Net income growth | 11.3% | −74.4% | 324.2% | −6.6% | −7.4% | −18.9% | 11.2% | 2.5% | −39.1% | 88.5% |
| EPS growth | 13.0% | −73.7% | 369.1% | 2.1% | −4.4% | −16.5% | 17.8% | 3.1% | −39.5% | 88.2% |
| FCF growth | 5.2% | 9.3% | 0.4% | −19.2% | 15.9% | −15.3% | 4.8% | −16.2% | 41.2% | −22.1% |
| Share count change | −1.6% | −2.5% | −9.5% | −8.4% | −3.1% | −2.9% | −5.6% | −0.6% | 0.6% | 0.2% |
| Financial health | ||||||||||
| Net debt / EBITDA | 2.6x | −0.5x | 0.4x | 1.8x | 1.8x | 2.3x | 2.3x | 4.5x | 3.8x | 3.2x |
| Debt / equity | 1.2x | 1.4x | 2.7x | 3.1x | 3.5x | 5.0x | 10.6x | 10.4x | 10.2x | 6.3x |
| Interest coverage | 7.8x | 7.7x | 7.4x | 7.5x | 7.2x | 6.4x | 6.8x | 2.8x | 2.3x | 3.3x |
| Current ratio | 4.1x | 5.5x | 2.8x | 1.4x | 1.8x | 1.6x | 1.4x | 1.7x | 1.3x | 1.1x |
| Quick ratio | 3.9x | 5.2x | 2.6x | 1.2x | 1.5x | 1.3x | 1.1x | 1.1x | 1.0x | 0.9x |
| Capital allocation | ||||||||||
| Capex / revenue | 3.2% | 2.9% | 3.1% | 2.7% | 2.4% | 3.4% | 3.6% | 3.9% | 3.3% | 5.1% |
| Stock comp / revenue | 1.4% | 1.4% | 1.3% | 1.3% | 1.3% | 1.3% | 1.5% | 1.5% | 1.6% | 1.3% |
| Payouts / FCF | 62.0% | 62.1% | 201.8% | 131.4% | 73.2% | 107.2% | 120.2% | 61.9% | 48.4% | 63.3% |
| Quality scores | ||||||||||
| Piotroski F-score | 7.0 | 7.0 | 7.0 | 6.0 | 7.0 | 5.0 | 7.0 | 6.0 | 4.0 | 7.0 |
| Altman Z'' | 4.4 | 4.4 | 2.8 | 0.7 | 1.0 | 0.4 | 0.3 | 0.5 | 0.1 | 0.1 |
| Accruals ratio | −3.5% | −11.7% | −4.0% | −2.1% | −5.3% | −5.4% | −5.0% | −2.2% | −7.8% | −2.5% |
Source: SEC EDGAR XBRL filings (CIK 0000318154). Data updated October 9, 2026. Quarterly fourth quarters are the full year minus the first nine months. For information only — not investment advice. Check the original filings before relying on any figure.