Regeneron Pharmaceuticals
REGN Nasdaq Biotechnology Financials FY2016βFY2025
Regeneron Pharmaceuticals' revenue rose 1.0% to $14.3 billion in fiscal 2025. Its operating margin was 24.9%, down from 28.1% a year earlier. Free cash flow was $4.1 billion, up 11.3%. It paid out $3.8 billion in dividends and buybacks, 93% of free cash flow. The diluted share count fell 5.7%.
What Regeneron Pharmaceuticals does
No business description yet.
- Legal name
- REGENERON PHARMACEUTICALS, INC.
- Fiscal year ends
- December 31, 2025
- Latest annual report
- β
- Accession Β· CIK
- 0000872589-26-000008
0000872589
Revenue and margins
Regeneron Pharmaceuticals had $14.3B of revenue in fiscal 2025, up 1.0% on the year before.
Net income and earnings per share
From fiscal 2016 to 2025, diluted EPS grew 20.6% a year. Loss periods are shown in red.
Returns on capital
After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.
Cash flow
Free cash flow was $4.1B in fiscal 2025, 28.5% of revenue. Cash from operations minus capital spending.
Dividends, buybacks and share count
Regeneron Pharmaceuticals returned $3.8B to shareholders in fiscal 2025, 93% of free cash flow. The diluted share count fell 5.7%.
Value Regeneron Pharmaceuticals yourself
Change the assumptions and see what they imply per share. These are models, not forecasts or price targets β the answer depends entirely on what you put in.
Discounted cash flow
Value per share
β
Adds net cash of $5.9B and divides by 108.6M diluted shares. Ten years of cash flows plus a terminal value, discounted to today.
Earnings multiple
Value per share
β
Reference multiples: today 19.9x Β· peers 27.3x Β· sector 28.4x.
Balance sheet
Cash, debt and the ratios that show how comfortably Regeneron Pharmaceuticals can carry it.
| Fiscal year end | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|
| Cash and short-term investments | $5.7B | $7.7B | $10.8B | $9.0B | $8.6B |
| Debt incl. finance leases | $2.7B | $2.7B | $2.7B | $2.7B | $2.7B |
| Net debt / EBITDA | β0.3x | β1.0x | β1.8x | β1.4x | β1.4x |
| Debt / equity | 0.1x | 0.1x | 0.1x | 0.1x | 0.1x |
| Interest coverage | 156.1x | 79.8x | 55.4x | 72.3x | 81.7x |
| Current ratio | 3.6x | 5.1x | 5.7x | 4.7x | 4.1x |
| Quick ratio | 3.1x | 4.3x | 4.9x | 4.0x | 3.4x |
| Total assets | $25.4B | $29.2B | $33.1B | $37.8B | $40.6B |
| Total liabilities | $6.7B | $6.6B | $7.1B | $8.4B | $9.3B |
| Shareholders' equity | $18.8B | $22.7B | $26.0B | $29.4B | $31.3B |
| Net debt (β = net cash) | β$3.0B | β$5.0B | β$8.1B | β$6.3B | β$5.9B |
Insider trades
Open-market purchases and sales by officers, directors and 10% owners, from Form 4 filings. 'Plan' marks trades under a pre-arranged Rule 10b5-1 plan.
Bought, 12 months
$0.0M
0 insiders
Sold, 12 months
$9.7M
6 insiders
Of sales under plans
100%
$9.7M
| Date | Insider | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| Oct 14, 2026 | Andrew J MurphyCo-Chief Scientific Officer | Sold plan | 4,147 | $772.70 | $3.2M | Form 4 |
| Sep 3, 2026 | Marion McCourtEVP Commercial | Sold plan | 1,131 | $857.39 | $1.0M | Form 4 |
| Sep 2, 2026 | Kathryn GuariniDirector | Sold plan | 400 | $850.00 | $0.3M | Form 4 |
| Sep 2, 2026 | Marion McCourtEVP Commercial | Sold plan | 1,215 | $850.00 | $1.0M | Form 4 |
| Aug 10, 2026 | Huda Y ZoghbiDirector | Sold plan | 800 | $800.00 | $0.6M | Form 4 |
| Aug 10, 2026 | Kathryn GuariniDirector | Sold plan | 400 | $800.00 | $0.3M | Form 4 |
| Jul 2, 2026 | Arthur F RyanDirector | Sold plan | 200 | $650.15 | $0.1M | Form 4 |
| May 1, 2026 | Arthur F RyanDirector | Sold plan | 100 | $705.24 | $0.1M | Form 4 |
| Apr 1, 2026 | Arthur F RyanDirector | Sold plan | 100 | $777.27 | $0.1M | Form 4 |
| Mar 2, 2026 | Arthur F RyanDirector | Sold plan | 100 | $785.50 | $0.1M | Form 4 |
| Feb 19, 2026 | Huda Y ZoghbiDirector | Sold plan | 1,638 | $781.33 | $1.3M | Form 4 |
| Feb 9, 2026 | Jason PitofskySVP Controller | Sold plan | 2,036 | $778.52 | $1.6M | Form 4 |
Piotroski F-score
Nine pass/fail tests of profitability, funding and efficiency. 8β9 is strong, 0β2 weak.
| Test | FY23 | FY24 | FY25 |
|---|---|---|---|
| Net income is positive | β | β | β |
| Cash from operations is positive | β | β | β |
| Return on assets rose | β | β | β |
| Cash from operations exceeds net income | β | β | β |
| Debt fell relative to assets | β | β | β |
| Current ratio rose | β | β | β |
| Share count didn't rise | β | β | β |
| Gross margin rose | β | β | β |
| Revenue rose relative to assets | β | β | β |
| F-score | 5 / 8 | 4 / 8 | 5 / 8 |
| Accruals ratio | β2.1% | β0.0% | β1.2% |
| Altman Z'' | 10.53 | 9.67 | 9.21 |
Similar companies
Each company's latest fiscal year. Fiscal years end in different months, so periods don't line up exactly.
| Company | Market cap | Growth | Op. margin | FCF margin | ROIC | P/E | F-score | |
|---|---|---|---|---|---|---|---|---|
| Regeneron Pharmaceuticals REGN | $85.3B | 1.0% | 25.0% | 28.5% | 12.7% | 19.9x | 5 | |
| Vertex Pharmaceuticals VRTX | $133.7B | 8.9% | 34.8% | 26.6% | 31.5% | 30.5x | 6 | Compare β |
| Biogen BIIB | $37.2B | 2.2% | β | 20.7% | 7.3% | 27.0x | 5 | Compare β |
| Gilead Sciences GILD | $194.0B | 2.4% | 34.0% | 32.1% | 23.0% | β | 8 | Compare β |
| Amgen AMGN | $239.0B | 10.0% | 24.7% | 22.0% | 14.4% | 27.3x | 7 | Compare β |
10 years of figures
US$ millions unless stated. Hover a ratio's name for its definition.
| Fiscal year | FY16 | FY17 | FY18 | FY19 | FY20 | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|---|---|---|---|---|
| Income statement | ||||||||||
| Revenue | $4.9B | $5.9B | $5.1B | $6.6B | $8.5B | $16.1B | $12.2B | $13.1B | $14.2B | $14.3B |
| Gross profit | $4.7B | $5.7B | $4.9B | $6.2B | β | β | β | β | β | β |
| Research and development | $2.1B | $2.1B | $1.5B | $2.5B | $2.6B | $2.9B | $3.6B | $4.4B | $5.1B | $5.9B |
| Operating income | $1.3B | $2.1B | $2.5B | $2.2B | $3.6B | $8.9B | $4.7B | $4.0B | $4.0B | $3.6B |
| Interest expense | $7.2M | $25.1M | $28.2M | $30.2M | $56.9M | $57.3M | $59.4M | $73.0M | $55.2M | $43.8M |
| Pretax income | $1.3B | $2.1B | $2.6B | $2.4B | $3.8B | $9.3B | $4.9B | $4.2B | $4.8B | $5.2B |
| Income tax | $434M | $880M | $109M | $313M | $297M | $1.3B | $520M | $246M | $367M | $726M |
| Net income | $896M | $1.2B | $2.4B | $2.1B | $3.5B | $8.1B | $4.3B | $4.0B | $4.4B | $4.5B |
| Diluted EPS | $7.70 | $10.34 | $21.29 | $18.46 | $30.52 | $71.97 | $38.22 | $34.77 | $38.34 | $41.48 |
| Diluted shares | 0.12B | 0.12B | 0.11B | 0.11B | 0.12B | 0.11B | 0.11B | 0.11B | 0.12B | 0.11B |
| Cash flow | ||||||||||
| Cash from operations | $1.5B | $1.3B | $2.2B | $2.4B | $2.6B | $7.1B | $5.0B | $4.6B | $4.4B | $5.0B |
| Capital expenditure | $512M | $273M | $383M | $430M | $615M | $552M | $590M | $719M | $756M | $898M |
| Free cash flow | $974M | $1.0B | $1.8B | $2.0B | $2.0B | $6.5B | $4.4B | $3.9B | $3.7B | $4.1B |
| Depreciation and amortization | $105M | $146M | $148M | $210M | $236M | $286M | $341M | $421M | $483M | $544M |
| Stock-based compensation | $560M | $507M | $427M | $464M | $432M | $602M | $725M | $885M | $983M | $994M |
| Acquisitions | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $230M | $54.9M | $16.5M | $3.3M |
| Share buybacks | $0.0M | $0.0M | $4.4M | $276M | $5.8B | $1.6B | $2.1B | $2.2B | $2.6B | $3.4B |
| Dividends paid | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $370M |
| Dividends and buybacks | $0.0M | $0.0M | $4.4M | $276M | $5.8B | $1.6B | $2.1B | $2.2B | $2.6B | $3.8B |
| Balance sheet | ||||||||||
| Cash and short-term investments | $1.0B | $1.4B | $2.8B | $3.2B | $3.6B | $5.7B | $7.7B | $10.8B | $9.0B | $8.6B |
| Total debt | $0.0M | $0.0M | $0.0M | $0.0M | $2.0B | $2.0B | $2.0B | $2.0B | $2.0B | $2.0B |
| Finance lease liabilities | $0.0M | $0.0M | $0.0M | $714M | $717M | $720M | $720M | $720M | $720M | $720M |
| Current assets | $3.2B | $4.3B | $6.4B | $7.7B | $9.8B | $14.0B | $15.9B | $19.5B | $18.7B | $18.0B |
| Current liabilities | $1.2B | $1.1B | $1.4B | $2.1B | $2.7B | $3.9B | $3.1B | $3.4B | $3.9B | $4.4B |
| Inventory | $399M | $726M | $1.2B | $1.4B | $1.9B | $2.0B | $2.4B | $2.6B | $3.1B | $3.2B |
| Property and equipment, net | $2.1B | $2.4B | $2.6B | $2.9B | $3.2B | $3.5B | $3.8B | $4.1B | $4.6B | $5.1B |
| Total assets | $7.0B | $8.8B | $11.7B | $14.8B | $17.2B | $25.4B | $29.2B | $33.1B | $37.8B | $40.6B |
| Total liabilities | $2.5B | $2.6B | $3.0B | $3.7B | $6.1B | $6.7B | $6.6B | $7.1B | $8.4B | $9.3B |
| Shareholders' equity | $4.4B | $6.1B | $8.8B | $11.1B | $11.0B | $18.8B | $22.7B | $26.0B | $29.4B | $31.3B |
| Margins | ||||||||||
| Gross margin | 96.0% | 96.6% | 95.4% | 93.9% | β | β | β | β | β | β |
| Operating margin | 27.4% | 35.4% | 49.3% | 33.7% | 42.1% | 55.7% | 38.9% | 30.9% | 28.1% | 25.0% |
| EBITDA margin | 29.5% | 37.9% | 52.1% | 36.9% | 44.9% | 57.5% | 41.7% | 34.1% | 31.5% | 28.7% |
| Net margin | 18.4% | 20.4% | 47.5% | 32.3% | 41.4% | 50.3% | 35.6% | 30.1% | 31.1% | 31.4% |
| FCF margin | 20.0% | 17.6% | 35.2% | 30.5% | 23.6% | 40.6% | 36.4% | 29.5% | 25.8% | 28.5% |
| Returns | ||||||||||
| Return on capital | 29.8% | 29.4% | 45.4% | 26.5% | 35.2% | 59.8% | 25.3% | 21.5% | 18.0% | 12.7% |
| Return on capital employed | 25.3% | 31.1% | 28.3% | 19.2% | 26.3% | 49.8% | 19.9% | 14.5% | 12.6% | 10.2% |
| Return on equity | 22.1% | 22.6% | 32.8% | 21.3% | 31.8% | 54.2% | 20.9% | 16.3% | 16.0% | 14.9% |
| Return on assets | 14.2% | 15.2% | 23.9% | 15.9% | 22.0% | 37.9% | 15.9% | 12.7% | 12.5% | 11.5% |
| Growth | ||||||||||
| Revenue growth | 18.4% | 20.8% | β12.4% | 27.4% | 29.6% | 89.1% | β24.3% | 7.8% | 8.3% | 1.0% |
| Net income growth | 40.8% | 33.8% | 104.0% | β13.4% | 66.1% | 129.9% | β46.3% | β8.9% | 11.6% | 2.1% |
| EPS growth | 39.5% | 34.3% | 105.9% | β13.3% | 65.3% | 135.8% | β46.9% | β9.0% | 10.3% | 8.2% |
| FCF growth | 49.2% | 6.2% | 75.2% | 10.4% | 0.2% | 225.9% | β32.2% | β12.4% | β5.4% | 11.4% |
| Share count change | 0.9% | β0.3% | β1.0% | β0.2% | 0.4% | β2.5% | 1.2% | 0.2% | 1.2% | β5.7% |
| Financial health | ||||||||||
| Net debt / EBITDA | β0.7x | β0.6x | β1.1x | β1.0x | β0.2x | β0.3x | β1.0x | β1.8x | β1.4x | β1.4x |
| Debt / equity | 0.0x | 0.0x | 0.0x | 0.1x | 0.2x | 0.1x | 0.1x | 0.1x | 0.1x | 0.1x |
| Interest coverage | 184.8x | 82.9x | 89.9x | 73.2x | 62.9x | 156.1x | 79.8x | 55.4x | 72.3x | 81.7x |
| Current ratio | 2.6x | 3.8x | 4.5x | 3.7x | 3.6x | 3.6x | 5.1x | 5.7x | 4.7x | 4.1x |
| Quick ratio | 2.2x | 3.2x | 3.7x | 3.0x | 2.9x | 3.1x | 4.3x | 4.9x | 4.0x | 3.4x |
| Capital allocation | ||||||||||
| Capex / revenue | 10.5% | 4.6% | 7.5% | 6.6% | 7.2% | 3.4% | 4.9% | 5.5% | 5.3% | 6.3% |
| Stock comp / revenue | 11.5% | 8.6% | 8.3% | 7.1% | 5.1% | 3.7% | 6.0% | 6.8% | 6.9% | 6.9% |
| Payouts / FCF | 0.0% | 0.0% | 0.2% | 13.8% | 291.8% | 25.2% | 47.1% | 57.7% | 71.0% | 93.3% |
| Quality scores | ||||||||||
| Piotroski F-score | 4.0 | 7.0 | 5.0 | 4.0 | 4.0 | 6.0 | 5.0 | 5.0 | 4.0 | 5.0 |
| Altman Z'' | 5.8 | 7.6 | 8.8 | 8.2 | 8.1 | 10.4 | 10.2 | 10.5 | 9.7 | 9.2 |
| Accruals ratio | β9.4% | β1.4% | 2.4% | β2.4% | 5.6% | 4.7% | β2.5% | β2.1% | β0.0% | β1.2% |
Source: SEC EDGAR XBRL filings (CIK 0000872589). Data updated October 9, 2026. Quarterly fourth quarters are the full year minus the first nine months. For information only β not investment advice. Check the original filings before relying on any figure.