Neurocrine Biosciences
NBIX Nasdaq Biotechnology Financials FY2016βFY2025
Neurocrine Biosciences' revenue rose 21.4% to $2.9 billion in fiscal 2025. Its operating margin was 21.6%, down from 24.2% a year earlier. Free cash flow was $749 million, up 34.4%. It paid out $168 million in dividends and buybacks, 22% of free cash flow. The diluted share count fell 1.2%.
About these figures. Neurocrine's interest coverage is blank from 2025: it repaid its convertible notes in 2024 and reported no interest expense.
What Neurocrine Biosciences does
No business description yet.
- Legal name
- NEUROCRINE BIOSCIENCES INC
- Fiscal year ends
- December 31, 2025
- Latest annual report
- β
- Accession Β· CIK
- 0000914475-26-000007
0000914475
Revenue and margins
Neurocrine Biosciences had $2.9B of revenue in fiscal 2025, up 21.5% on the year before.
Net income and earnings per share
Loss periods are shown in red.
Returns on capital
After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.
Cash flow
Free cash flow was $749M in fiscal 2025, 26.2% of revenue. Cash from operations minus capital spending.
Dividends, buybacks and share count
Neurocrine Biosciences returned $168M to shareholders in fiscal 2025, 22% of free cash flow. The diluted share count fell 1.2%.
Value Neurocrine Biosciences yourself
Change the assumptions and see what they imply per share. These are models, not forecasts or price targets β the answer depends entirely on what you put in.
Discounted cash flow
Value per share
β
Adds net cash of $1.5B and divides by 102.5M diluted shares. Ten years of cash flows plus a terminal value, discounted to today.
Earnings multiple
Value per share
β
Reference multiples: today 20.9x Β· peers 21.0x Β· sector 28.4x.
Balance sheet
Cash, debt and the ratios that show how comfortably Neurocrine Biosciences can carry it.
| Fiscal year end | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|
| Cash and short-term investments | $711M | $989M | $1.0B | $1.1B | $1.5B |
| Debt incl. finance leases | $335M | $169M | $170M | $0.0M | $0.0M |
| Net debt / EBITDA | β3.3x | β3.1x | β3.2x | β1.8x | β2.3x |
| Debt / equity | 0.2x | 0.1x | 0.1x | 0.0x | 0.0x |
| Interest coverage | 4.0x | 35.1x | 54.5x | 356.6x | β |
| Current ratio | 4.0x | 2.7x | 2.5x | 3.4x | 3.4x |
| Quick ratio | 3.8x | 2.6x | 2.4x | 3.3x | 3.3x |
| Total assets | $2.1B | $2.4B | $3.3B | $3.7B | $4.6B |
| Total liabilities | $699M | $661M | $1.0B | $1.1B | $1.4B |
| Shareholders' equity | $1.4B | $1.7B | $2.2B | $2.6B | $3.3B |
| Net debt (β = net cash) | β$376M | β$820M | β$861M | β$1.1B | β$1.5B |
Insider trades
Open-market purchases and sales by officers, directors and 10% owners, from Form 4 filings. 'Plan' marks trades under a pre-arranged Rule 10b5-1 plan.
Bought, 12 months
$0.0M
0 insiders
Sold, 12 months
$12.1M
7 insiders
Of sales under plans
100%
$12.1M
| Date | Insider | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| Sep 14, 2026 | David W. BoyerChief Corp. Affairs Officer | Sold plan | 826 | $157.45 | $0.1M | Form 4 |
| Sep 14, 2026 | Matt AbernethyChief Financial Officer | Sold plan | 2,311 | $157.20 | $0.4M | Form 4 |
| Sep 9, 2026 | Eric BenevichChief Commercial Officer | Sold plan | 2,154 | $154.61 | $0.3M | Form 4 |
| Jul 28, 2026 | Leslie Norwalk VDirector | Sold plan | 1,250 | $182.01 | $0.2M | Form 4 |
| Jul 10, 2026 | Ingrid DelaetChief Regulatory Officer | Sold plan | 4,367 | $181.02 | $0.8M | Form 4 |
| Jul 9, 2026 | Darin LippoldtChief Legal Officer | Sold plan | 10,000 | $179.60 | $1.8M | Form 4 |
| Jul 9, 2026 | Ingrid DelaetChief Regulatory Officer | Sold plan | 8,433 | $178.72 | $1.5M | Form 4 |
| Jul 8, 2026 | Ingrid DelaetChief Regulatory Officer | Sold plan | 2,737 | $178.54 | $0.5M | Form 4 |
| Jul 7, 2026 | Ingrid DelaetChief Regulatory Officer | Sold plan | 3,401 | $178.57 | $0.6M | Form 4 |
| Jun 29, 2026 | Darin LippoldtChief Legal Officer | Sold plan | 9,800 | $170.16 | $1.7M | Form 4 |
| Jun 26, 2026 | Darin LippoldtChief Legal Officer | Sold plan | 200 | $169.57 | $0.0M | Form 4 |
| Jun 5, 2026 | Stephen A SherwinDirector | Sold plan | 25,000 | $165.32 | $4.1M | Form 4 |
Piotroski F-score
Nine pass/fail tests of profitability, funding and efficiency. 8β9 is strong, 0β2 weak.
| Test | FY23 | FY24 | FY25 |
|---|---|---|---|
| Net income is positive | β | β | β |
| Cash from operations is positive | β | β | β |
| Return on assets rose | β | β | β |
| Cash from operations exceeds net income | β | β | β |
| Debt fell relative to assets | β | β | β |
| Current ratio rose | β | β | β |
| Share count didn't rise | β | β | β |
| Gross margin rose | β | β | β |
| Revenue rose relative to assets | β | β | β |
| F-score | 6 / 9 | 6 / 9 | 6 / 9 |
| Accruals ratio | β5.0% | β7.3% | β7.3% |
| Altman Z'' | 4.58 | 5.61 | 6.21 |
Similar companies
Each company's latest fiscal year. Fiscal years end in different months, so periods don't line up exactly.
| Company | Market cap | Growth | Op. margin | FCF margin | ROIC | P/E | F-score | |
|---|---|---|---|---|---|---|---|---|
| Neurocrine Biosciences NBIX | $14.9B | 21.5% | 21.6% | 26.2% | 25.6% | 20.9x | 6 | |
| Fortrea FTRE | $2.2B | 1.0% | β32.0% | 3.2% | β36.2% | β | β | Compare β |
| United Therapeutics UTHR | $26.9B | 10.6% | 46.9% | 32.7% | β | 21.0x | β | Compare β |
| BioMarin Pharmaceutical BMRN | $10.9B | 12.9% | 12.7% | 22.5% | 5.8% | 151.2x | 5 | Compare β |
| Exelixis EXEL | $16.8B | 7.0% | 37.6% | 37.8% | 64.9% | 20.3x | 6 | Compare β |
10 years of figures
US$ millions unless stated. Hover a ratio's name for its definition.
| Fiscal year | FY16 | FY17 | FY18 | FY19 | FY20 | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|---|---|---|---|---|
| Income statement | ||||||||||
| Revenue | $15.0M | $162M | $451M | $788M | $1.0B | $1.1B | $1.5B | $1.9B | $2.4B | $2.9B |
| Gross profit | $15.0M | $160M | $446M | β | $1.0B | $1.1B | $1.5B | $1.8B | $2.3B | $2.8B |
| Research and development | $94.3M | $122M | $161M | β | $275M | $328M | $464M | $565M | $731M | $1.0B |
| Operating income | β$147M | β$131M | $36.8M | $72.3M | $163M | $103M | $249M | $251M | $571M | $619M |
| Interest expense | $0.0M | $19.5M | $30.5M | $32.0M | $32.8M | $25.8M | $7.1M | $4.6M | $1.6M | $0.0M |
| Pretax income | β$141M | β$143M | $21.8M | $46.5M | $107M | $101M | $214M | $332M | $486M | $705M |
| Income tax | $0.0M | $0.0M | $0.7M | $9.5M | β$301M | $11.8M | $59.4M | $82.4M | $145M | $227M |
| Net income | β$141M | β$143M | $21.1M | $37.0M | $407M | $89.6M | $155M | $250M | $341M | $479M |
| Diluted EPS | β$1.63 | β$1.62 | $0.22 | $0.39 | $4.16 | $0.92 | $1.56 | $2.47 | $3.29 | $4.67 |
| Diluted shares | 0.09B | 0.09B | 0.10B | 0.10B | 0.10B | 0.10B | 0.10B | 0.10B | 0.10B | 0.10B |
| Cash flow | ||||||||||
| Cash from operations | β$106M | β$94.3M | $101M | $147M | $229M | $257M | $339M | $390M | $595M | $783M |
| Capital expenditure | $4.1M | $6.9M | $24.8M | $14.7M | $10.9M | $23.4M | $16.5M | $28.3M | $38.2M | $34.0M |
| Free cash flow | β$110M | β$101M | $76.6M | $132M | $218M | $233M | $323M | $362M | $557M | $749M |
| Depreciation and amortization | $1.5M | $2.4M | $4.0M | $7.4M | $8.6M | $10.9M | $15.6M | $21.3M | $27.1M | $30.1M |
| Stock-based compensation | $28.5M | $42.5M | $58.1M | $75.3M | $100M | $134M | $173M | $194M | $196M | $218M |
| Acquisitions | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $42.7M | $0.0M | $0.0M | $0.0M |
| Share buybacks | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $300M | $168M |
| Dividends paid | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M |
| Dividends and buybacks | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $300M | $168M |
| Balance sheet | ||||||||||
| Cash and short-term investments | $83.3M | $516M | $651M | $671M | $801M | $711M | $989M | $1.0B | $1.1B | $1.5B |
| Total debt | $0.0M | $370M | $389M | $409M | $318M | $335M | $169M | $170M | $0.0M | $0.0M |
| Finance lease liabilities | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M |
| Current assets | $310M | $555M | $738M | $831M | $1.0B | $973M | $1.5B | $1.6B | $1.7B | $2.5B |
| Current liabilities | $30.4M | $54.4M | $88.2M | $565M | $187M | $246M | $538M | $655M | $508M | $743M |
| Inventory | $0.0M | $1.0M | $10.9M | $17.3M | $28.0M | $30.5M | $35.1M | $38.3M | $57.4M | $69.0M |
| Property and equipment, net | $6.3M | $10.8M | $33.9M | $41.9M | $44.6M | $58.6M | $58.6M | $70.8M | $82.6M | $89.8M |
| Total assets | $365M | $818M | $993M | $1.3B | $1.7B | $2.1B | $2.4B | $3.3B | $3.7B | $4.6B |
| Total liabilities | $50.2M | $446M | $512M | $669M | $609M | $699M | $661M | $1.0B | $1.1B | $1.4B |
| Shareholders' equity | $315M | $372M | $481M | $637M | $1.1B | $1.4B | $1.7B | $2.2B | $2.6B | $3.3B |
| Margins | ||||||||||
| Gross margin | 100.0% | 99.2% | 98.9% | β | 99.0% | 98.7% | 98.4% | 97.9% | 98.6% | 98.2% |
| Operating margin | β982.5% | β81.3% | 8.2% | 9.2% | 15.6% | 9.0% | 16.7% | 13.3% | 24.2% | 21.6% |
| EBITDA margin | β972.8% | β79.8% | 9.1% | 10.1% | 16.4% | 10.0% | 17.8% | 14.4% | 25.4% | 22.7% |
| Net margin | β940.6% | β88.2% | 4.7% | 4.7% | 38.9% | 7.9% | 10.4% | 13.2% | 14.5% | 16.7% |
| FCF margin | β735.3% | β62.7% | 17.0% | 16.8% | 20.8% | 20.6% | 21.7% | 19.2% | 23.7% | 26.2% |
| Returns | ||||||||||
| Return on capital | β | β45.4% | 16.0% | 19.4% | 32.0% | 11.0% | 19.1% | 16.7% | 27.8% | 25.6% |
| Return on capital employed | β37.6% | β23.9% | 4.4% | 8.8% | 14.2% | 6.1% | 13.6% | 11.3% | 19.7% | 17.4% |
| Return on equity | β38.2% | β41.5% | 5.0% | 6.6% | 46.2% | 7.2% | 10.0% | 12.7% | 14.2% | 16.4% |
| Return on assets | β33.6% | β24.1% | 2.3% | 3.2% | 26.8% | 4.7% | 7.0% | 8.9% | 9.8% | 11.5% |
| Growth | ||||||||||
| Revenue growth | β24.1% | 977.5% | 179.2% | 74.7% | 32.7% | 8.4% | 31.3% | 26.8% | 24.8% | 21.5% |
| Net income growth | β | β | β | 75.4% | 1,000.8% | β78.0% | 72.4% | 61.6% | 36.7% | 40.2% |
| EPS growth | β | β | β | 77.3% | 966.7% | β77.9% | 69.6% | 58.3% | 33.2% | 42.0% |
| FCF growth | β | β | β | 72.7% | 64.5% | 7.1% | 38.5% | 12.0% | 54.1% | 34.4% |
| Share count change | 2.6% | 1.6% | 8.3% | 0.3% | 2.2% | 0.1% | 1.0% | 2.1% | 2.7% | β1.2% |
| Financial health | ||||||||||
| Net debt / EBITDA | β | β | β6.4x | β3.3x | β2.8x | β3.3x | β3.1x | β3.2x | β1.8x | β2.3x |
| Debt / equity | 0.0x | 1.0x | 0.8x | 0.6x | 0.3x | 0.2x | 0.1x | 0.1x | 0.0x | 0.0x |
| Interest coverage | β | β6.7x | 1.2x | 2.3x | 5.0x | 4.0x | 35.1x | 54.5x | 356.6x | β |
| Current ratio | 10.2x | 10.2x | 8.4x | 1.5x | 5.5x | 4.0x | 2.7x | 2.5x | 3.4x | 3.4x |
| Quick ratio | 10.2x | 10.2x | 8.2x | 1.4x | 5.3x | 3.8x | 2.6x | 2.4x | 3.3x | 3.3x |
| Capital allocation | ||||||||||
| Capex / revenue | 27.4% | 4.3% | 5.5% | 1.9% | 1.0% | 2.1% | 1.1% | 1.5% | 1.6% | 1.2% |
| Stock comp / revenue | 189.8% | 26.3% | 12.9% | 9.6% | 9.6% | 11.8% | 11.6% | 10.3% | 8.3% | 7.6% |
| Payouts / FCF | β | β | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 53.8% | 22.4% |
| Quality scores | ||||||||||
| Piotroski F-score | β | 2.0 | 6.0 | 6.0 | 6.0 | 4.0 | 6.0 | 6.0 | 6.0 | 6.0 |
| Altman Z'' | β0.5 | β1.0 | 1.7 | β0.1 | 4.4 | 3.7 | 5.4 | 4.6 | 5.6 | 6.2 |
| Accruals ratio | β8.3% | β8.2% | β8.9% | β9.6% | 11.8% | β8.8% | β8.3% | β5.0% | β7.3% | β7.3% |
Source: SEC EDGAR XBRL filings (CIK 0000914475). Data updated October 16, 2026. Quarterly fourth quarters are the full year minus the first nine months. For information only β not investment advice. Check the original filings before relying on any figure.