ILMN Nasdaq Life Sciences Tools & Services Financials FY2016βFY2025
Illumina had $4.3B of revenue in fiscal 2025, down 0.7% on the year before. Over five years, revenue changed +6.0% a year on average.
Hi! I read Illuminaβs latest annual report (fiscal 2025). Here is what stands out:
Good So-so Weak
Are sales growing?
β0.7%
No. Sales fell 0.7% last year.
Does it make a profit?
19.6%
Yes. It keeps 19.6% of every sale as profit.
Does profit turn into cash?
21.4%
Yes. 21.4% of sales ends up as free cash.
Is debt under control?
0.3x
Yes. It could repay its debt with 0.3 years of operating profit.
How healthy are the accounts?
8 / 9
Solid. It passes 8 of 9 health tests.
How is the share priced?
50.3x
One share costs 50.3 times its yearly profit per share. Typical for its sector: 27.9x.
Rules of thumb on reported numbers. A starting point, not a recommendation.
Is it selling more, and how much does it keep?
In plain words: Every quarter, companies publish how much they sold and earned. These are the days Illumina did it, and the next one. Share prices often move a lot on those days.
Next results
October 29, 2026
Thursday Β· in 4 days
| Date | Results for | Time | Source |
|---|---|---|---|
| Jul 30, 2026 | Q2 '26 | After the market closes | 8-K β |
| Apr 30, 2026 | Q1 '26 | After the market closes | 8-K β |
| Jan 13, 2026 | Q4 '25 | Before the market opens | 8-K β |
| Oct 30, 2025 | Q3 '25 | After the market closes | 8-K β |
| Jul 31, 2025 | Q2 '25 | After the market closes | 8-K β |
| May 8, 2025 | Q1 '25 | After the market closes | 8-K β |
| Jan 14, 2025 | Q4 '24 | Before the market opens | 8-K β |
| Nov 4, 2024 | Q3 '24 | After the market closes | 8-K β |
From SEC filings: the results press release (8-K) or, without one, the quarterly or annual report.
KIRA Β· Illumina had $4.3B of revenue in fiscal 2025, down 0.7% on the year before. Over five years, revenue changed +6.0% a year on average. Its operating margin was 18.6%, up 37.6Β pts: of every 100 in sales, about 19 is left after running the business.
In plain words: Revenue is all the money customers paid. The margins show how many cents of each dollar of sales are left over at each step: after making the product (gross), after running the business (operating) and after everything, tax included (net).
KIRA Β· Illumina made $850M of net profit in fiscal 2025. From fiscal 2016 to 2025, diluted EPS grew 6.6% a year.
Loss periods are shown in red.
In plain words: Net income is the profit left after every cost and tax. Earnings per share (EPS) splits that profit across every share, so it shows what one share earned.
How much cash comes in, and where does it go?
KIRA Β· Free cash flow was $931M in fiscal 2025, 21.4% of revenue.
Cash from operations minus capital spending.
In plain words: Profit on paper is not the same as cash in the bank. Free cash flow is the cash left after paying to run and maintain the business: the money it can hand back to shareholders, save or invest.
KIRA Β· Illumina returned $742M to shareholders in fiscal 2025, 80% of free cash flow. The diluted share count fell 1.9%.
In plain words: Companies hand cash back in two ways: dividends (cash paid to shareholders) and buybacks (buying back their own shares, so each remaining share owns a bigger slice).
KIRA Β· In the last 12 months, insiders sold $436M of shares on the open market and bought none.
Open-market purchases and sales by officers, directors and 10% owners, from Form 4 filings. βPlanβ marks trades under a pre-arranged Rule 10b5-1 plan.
In plain words: Insiders are the people who run or own a big part of the company. Buying with their own money can signal confidence; selling often has personal reasons, like taxes or diversifying.
Bought, 12 months
$0.0M
0 insiders
Sold, 12 months
$436M
2 insiders
Of sales under plans
0%
$0.2M
| Date | Insider | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| Sep 4, 2026 | Keith A. MeisterDirector | Sold | 119,501 | $218.40 | $26.1M | Form 4 |
| Sep 3, 2026 | Keith A. MeisterDirector | Sold | 75,951 | $218.23 | $16.6M | Form 4 |
| Sep 2, 2026 | Keith A. MeisterDirector | Sold | 68,108 | $213.28 | $14.5M | Form 4 |
| Aug 27, 2026 | Keith A. MeisterDirector | Sold | 138,379 | $228.89 | $31.7M | Form 4 |
| Aug 26, 2026 | Keith A. MeisterDirector | Sold | 106,543 | $225.46 | $24.0M | Form 4 |
| Aug 25, 2026 | Keith A. MeisterDirector | Sold | 131,019 | $225.51 | $29.5M | Form 4 |
| Aug 21, 2026 | Keith A. MeisterDirector | Sold | 299,336 | $217.96 | $65.2M | Form 4 |
| Aug 20, 2026 | Keith A. MeisterDirector | Sold | 285,238 | $213.86 | $61.0M | Form 4 |
| Aug 19, 2026 | Keith A. MeisterDirector | Sold | 95,000 | $203.29 | $19.3M | Form 4 |
| Aug 18, 2026 | Christensen Jakob WedelSVP, Strategy/Corp Development | Sold plan | 1,033 | $191.52 | $0.2M | Form 4 |
| Aug 5, 2026 | Keith A. MeisterDirector | Sold | 283,269 | $199.61 | $56.5M | Form 4 |
| Aug 4, 2026 | Keith A. MeisterDirector | Sold | 457,858 | $200.10 | $91.6M | Form 4 |
Can it carry its debts, and how well does it use its money?
KIRA Β· Illumina owes $356M more than it holds in cash, about 0.3 years of operating profit.
Cash, debt and the ratios that show how comfortably Illumina can carry it.
In plain words: What the company owns and what it owes. More cash than debt is a cushion for bad times; a lot of debt leaves less room when business slows down.
| Fiscal year end | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|
| Cash and short-term investments | $1.3B | $2.0B | $1.1B | $1.2B | $1.6B |
| Debt incl. finance leases | $702M | $2.0B | $1.5B | $2.0B | $2.0B |
| Net debt / EBITDA | β5.0x | β | β | β | 0.3x |
| Debt / equity | 0.1x | 0.3x | 0.3x | 0.8x | 0.7x |
| Interest coverage | β2.0x | β160.7x | β13.9x | β8.3x | 8.0x |
| Current ratio | 2.5x | 1.3x | 1.7x | 1.8x | 2.1x |
| Quick ratio | 2.1x | 1.1x | 1.3x | 1.4x | 1.7x |
| Total assets | $15.2B | $12.3B | $10.1B | $6.3B | $6.6B |
| Total liabilities | $4.5B | $5.7B | $4.4B | $3.9B | $3.9B |
| Shareholders' equity | $10.7B | $6.6B | $5.7B | $2.4B | $2.7B |
| Net debt (β = net cash) | β$637M | β$50.0M | $435M | $769M | $356M |
KIRA Β· Its return on capital was 20.3%: every 100 invested in the business earned about 20 in a year.
After-tax operating income as a share of the money invested in the business: debt plus equity, minus cash.
In plain words: How much profit the business makes on the money put into it. A higher percentage means each dollar invested works harder.
KIRA Β· Illumina passes 8 of 9 financial health tests (Piotroski F-score).
Nine pass/fail tests of profitability, funding and efficiency. 8β9 is strong, 0β2 weak.
In plain words: Nine yes/no tests of financial health, one point each. A green tick is a pass: 7 to 9 points is solid, 0 to 3 is weak.
| Test | FY23 | FY24 | FY25 |
|---|---|---|---|
| Net income is positive | β | β | β |
| Cash from operations is positive | β | β | β |
| Return on assets rose | β | β | β |
| Cash from operations exceeds net income | β | β | β |
| Debt fell relative to assets | β | β | β |
| Current ratio rose | β | β | β |
| Share count didn't rise | β | β | β |
| Gross margin rose | β | β | β |
| Revenue rose relative to assets | β | β | β |
| F-score | 6 / 9 | 5 / 9 | 8 / 9 |
| Accruals ratio | β14.7% | β25.1% | β3.5% |
| Altman Z'' | 1.34 | 0.35 | 3.04 |
What does the share cost, and how does it compare?
KIRA Β· At $269.42 a share, the company is worth $41.2B: 50.3 times its earnings of the last four quarters.
Change the assumptions and see what they imply per share. These are models, not forecasts or price targets β the answer depends entirely on what you put in.
In plain words: Move the sliders to try your own guesses about growth. The result is what one share would be worth if those guesses came true. Different guesses give very different answers.
Value per share
β
Adds net cash of β$356M and divides by 156.0M diluted shares. Ten years of cash flows plus a terminal value, discounted to today.
Value per share
β
Reference multiples: today 50.3x Β· peers β Β· sector 27.9x.
KIRA Β· Illumina grew sales faster than 2 of its 4 similar companies. Its P/E is higher than 1 of 1.
Each companyβs latest fiscal year. Fiscal years end in different months, so periods donβt line up exactly.
In plain words: The same numbers for similar companies, so you can tell whether a figure is high or low for this kind of business.
| Company | Market cap | Growth | Op. margin | FCF margin | ROIC | P/E | F-score | |
|---|---|---|---|---|---|---|---|---|
| Illumina ILMN | $41.2B | β0.7% | 18.6% | 21.4% | 20.3% | 50.3x | 8 | |
| Mettler Toledo MTD | $33.7B | 4.0% | β | 21.1% | 50.5% | 37.6x | 7 | Compare β |
| Charles River Laboratories CRL | $16.6B | β0.9% | 0.6% | 12.9% | 0.4% | β | 4 | Compare β |
| Waters WAT | $44.6B | 7.0% | 25.4% | 17.1% | 21.0% | β | 6 | Compare β |
| Avantor AVTR | $11.7B | β3.4% | β3.8% | 7.6% | β2.1% | β | 5 | Compare β |
Every number, year by year.
Amounts in USD. Hover a ratioβs name for its definition.
In plain words: Every number we have, year by year. Download it as a spreadsheet if you want to dig deeper.
| Fiscal year | FY16 | FY17 | FY18 | FY19 | FY20 | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|---|---|---|---|---|
| Income statement | ||||||||||
| Revenue | $2.4B | $2.8B | $3.3B | $3.5B | $3.2B | $4.5B | $4.6B | $4.5B | $4.4B | $4.3B |
| Gross profit | $1.7B | $1.8B | $2.3B | $2.5B | $2.2B | $3.2B | $3.0B | $2.7B | $2.9B | $2.9B |
| Research and development | $504M | $546M | $623M | $647M | $682M | $1.2B | $1.3B | $1.4B | $1.2B | $967M |
| Operating income | $587M | $606M | $883M | $985M | $580M | β$123M | β$4.2B | β$1.1B | β$833M | $807M |
| Interest expense | $33.0M | $37.0M | $57.0M | $52.0M | $49.0M | $61.0M | $26.0M | $77.0M | $100M | $101M |
| Pretax income | $561M | $1.0B | $894M | $1.1B | $856M | $884M | β$4.3B | β$1.1B | β$1.2B | $1.1B |
| Income tax | $133M | $365M | $112M | $128M | $200M | $122M | $68.0M | $44.0M | $44.0M | $236M |
| Net income | $463M | $726M | $826M | $1.0B | $656M | $762M | β$4.4B | β$1.2B | β$1.2B | $850M |
| Diluted EPS | $3.07 | $4.92 | $5.56 | $6.74 | $4.45 | $5.04 | β$28.00 | β$7.34 | β$7.69 | $5.45 |
| Diluted shares | 0.15B | 0.15B | 0.15B | 0.15B | 0.15B | 0.15B | 0.16B | 0.16B | 0.16B | 0.16B |
| Cash flow | ||||||||||
| Cash from operations | $779M | $875M | $1.1B | $1.1B | $1.1B | $545M | $392M | $478M | $837M | $1.1B |
| Capital expenditure | $260M | $310M | $296M | $209M | $189M | $208M | $286M | $195M | $128M | $148M |
| Free cash flow | $519M | $565M | $846M | $842M | $891M | $337M | $106M | $283M | $709M | $931M |
| Depreciation and amortization | $141M | $156M | $179M | $188M | $187M | $251M | $394M | $432M | $354M | $270M |
| Stock-based compensation | $129M | $164M | $193M | $194M | $194M | $754M | $366M | $380M | $370M | $275M |
| Acquisitions | $18.0M | $0.0M | $100M | $0.0M | $98.0M | $2.4B | $265M | $30.0M | $81.0M | $10.0M |
| Share buybacks | $249M | $251M | $201M | $324M | $736M | $0.0M | $0.0M | $0.0M | $116M | $742M |
| Dividends paid | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M |
| Dividends and buybacks | $249M | $251M | $201M | $324M | $736M | $0.0M | $0.0M | $0.0M | $116M | $742M |
| Balance sheet | ||||||||||
| Cash and short-term investments | $1.6B | $2.1B | $3.5B | $3.4B | $3.5B | $1.3B | $2.0B | $1.1B | $1.2B | $1.6B |
| Total debt | $1.1B | $1.2B | $2.0B | $1.1B | $1.2B | $702M | $2.0B | $1.5B | $2.0B | $2.0B |
| Finance lease liabilities | $9.0M | $113M | $269M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M | $0.0M |
| Current assets | $2.3B | $3.0B | $4.5B | $4.5B | $4.5B | $2.7B | $3.6B | $2.6B | $2.7B | $3.3B |
| Current liabilities | $705M | $746M | $1.8B | $665M | $1.2B | $1.1B | $2.8B | $1.6B | $1.5B | $1.6B |
| Inventory | $300M | $333M | $386M | $359M | $372M | $431M | $568M | $587M | $547M | $564M |
| Property and equipment, net | $713M | $931M | $1.1B | $889M | $922M | $1.0B | $1.1B | $1.0B | $815M | $759M |
| Total assets | $4.3B | $5.3B | $7.0B | $7.3B | $7.6B | $15.2B | $12.3B | $10.1B | $6.3B | $6.6B |
| Total liabilities | $2.0B | $2.5B | $3.1B | $2.7B | $2.9B | $4.5B | $5.7B | $4.4B | $3.9B | $3.9B |
| Shareholders' equity | $2.2B | $2.7B | $3.8B | $4.6B | $4.7B | $10.7B | $6.6B | $5.7B | $2.4B | $2.7B |
| Margins | ||||||||||
| Gross margin | 69.5% | 66.4% | 69.0% | 69.6% | 68.0% | 69.7% | 64.8% | 60.9% | 65.4% | 66.1% |
| Operating margin | 24.5% | 22.0% | 26.5% | 27.8% | 17.9% | β2.7% | β91.2% | β23.7% | β19.1% | 18.6% |
| EBITDA margin | 30.4% | 27.7% | 31.9% | 33.1% | 23.7% | 2.8% | β82.6% | β14.1% | β11.0% | 24.8% |
| Net margin | 19.3% | 26.4% | 24.8% | 28.3% | 20.3% | 16.8% | β96.1% | β25.8% | β28.0% | 19.6% |
| FCF margin | 21.6% | 20.5% | 25.4% | 23.8% | 27.5% | 7.5% | 2.3% | 6.3% | 16.2% | 21.4% |
| Returns | ||||||||||
| Return on capital | 26.9% | 21.4% | 34.3% | 35.3% | 18.7% | β1.7% | β39.7% | β13.3% | β14.1% | 20.3% |
| Return on capital employed | 17.6% | 15.0% | 18.3% | 16.7% | 8.9% | β1.2% | β35.4% | β11.9% | β12.5% | 16.4% |
| Return on equity | 22.9% | 29.4% | 25.4% | 23.9% | 14.1% | 9.9% | β50.8% | β18.8% | β30.1% | 33.4% |
| Return on assets | 11.6% | 15.2% | 13.5% | 14.0% | 8.8% | 6.7% | β32.1% | β10.4% | β14.9% | 13.1% |
| Growth | ||||||||||
| Revenue growth | 8.0% | 14.8% | 21.1% | 6.3% | β8.6% | 39.7% | 1.3% | β1.8% | β2.9% | β0.7% |
| Net income growth | 0.2% | 56.8% | 13.8% | 21.3% | β34.5% | 16.2% | β678.0% | β | β | β |
| EPS growth | β1.0% | 60.3% | 13.0% | 21.2% | β34.0% | 13.3% | β655.6% | β | β | β |
| FCF growth | β19.3% | 8.9% | 49.7% | β0.5% | 5.8% | β62.2% | β68.6% | 167.0% | 150.5% | 31.3% |
| Share count change | β0.7% | 0.0% | 0.7% | 0.0% | β0.7% | 2.0% | 4.0% | 0.6% | 0.6% | β1.9% |
| Financial health | ||||||||||
| Net debt / EBITDA | β0.7x | β1.1x | β1.2x | β1.9x | β3.0x | β5.0x | β | β | β | 0.3x |
| Debt / equity | 0.5x | 0.5x | 0.6x | 0.3x | 0.3x | 0.1x | 0.3x | 0.3x | 0.8x | 0.7x |
| Interest coverage | 17.8x | 16.4x | 15.5x | 18.9x | 11.8x | β2.0x | β160.7x | β13.9x | β8.3x | 8.0x |
| Current ratio | 3.3x | 4.0x | 2.5x | 6.7x | 3.6x | 2.5x | 1.3x | 1.7x | 1.8x | 2.1x |
| Quick ratio | 2.9x | 3.6x | 2.3x | 6.2x | 3.3x | 2.1x | 1.1x | 1.3x | 1.4x | 1.7x |
| Capital allocation | ||||||||||
| Capex / revenue | 10.8% | 11.3% | 8.9% | 5.9% | 5.8% | 4.6% | 6.2% | 4.3% | 2.9% | 3.4% |
| Stock comp / revenue | 5.4% | 6.0% | 5.8% | 5.5% | 6.0% | 16.7% | 8.0% | 8.4% | 8.5% | 6.3% |
| Payouts / FCF | 48.0% | 44.4% | 23.8% | 38.5% | 82.6% | 0.0% | 0.0% | 0.0% | 16.4% | 79.7% |
| Quality scores | ||||||||||
| Piotroski F-score | 5.0 | 7.0 | 4.0 | 7.0 | 5.0 | 6.0 | 2.0 | 6.0 | 5.0 | 8.0 |
| Altman Z'' | 5.7 | 6.1 | 6.1 | 7.9 | 7.1 | 4.3 | β0.3 | 1.3 | 0.4 | 3.0 |
| Accruals ratio | β7.9% | β3.1% | β5.2% | β0.7% | β5.7% | 1.9% | β34.9% | β14.7% | β25.1% | β3.5% |
Source: SEC EDGAR XBRL filings (CIK 0001110803). Data updated October 9, 2026. Quarterly fourth quarters are the full year minus the first nine months. For information only β not investment advice. Check the original filings before relying on any figure.
